A5055027996- Genomics and Phylogenetic Studies
- Marine Biology and Ecology Research
- Parasite Biology and Host Interactions
- Nematode management and characterization studies
- Genetic diversity and population structure
- Marine Ecology and Invasive Species
- Bioinformatics and Genomic Networks
- Cephalopods and Marine Biology
- Environmental DNA in Biodiversity Studies
- Genetics, Bioinformatics, and Biomedical Research
- Chromosomal and Genetic Variations
- Peatlands and Wetlands Ecology
- Algal biology and biofuel production
- Fossil Insects in Amber
- Photosynthetic Processes and Mechanisms
- Genetic factors in colorectal cancer
- Plant nutrient uptake and metabolism
- Cancer Genomics and Diagnostics
- Biomedical Text Mining and Ontologies
- Marine Invertebrate Physiology and Ecology
- Mitochondrial Function and Pathology
- Vehicle Routing Optimization Methods
- Planarian Biology and Electrostimulation
- Coastal wetland ecosystem dynamics
- RNA and protein synthesis mechanisms
Institute for Information Transmission Problems
2006-2024
Bioinformatics Institute
2023
Lomonosov Moscow State University
2001-2019
Yandex (Russia)
2016
Moscow State University
2013
Russian Academy of Sciences
2009
Two enigmatic groups of morphologically simple parasites invertebrates, the Dicyemida (syn. Rhombozoa) and Orthonectida, since 19th century have been usually considered as two classes phylum Mesozoa. Early molecular evidence suggested their relationship within Spiralia (=Lophotrochozoa), however high rates dicyemid orthonectid sequence evolution led to contradicting phylogeny reconstructions. Genomic data for orthonectids revealed that they are highly simplified spiralians possess a reduced...
The first part of the paper briefly overviews problem gene and species trees reconciliation with focus on defining algorithmic construction evolutionary scenario. Basic ideas are discussed for aspects mapping definitions, costs scenario, imposing time scales a incorporating horizontal transfers, binarization polytomous trees, scenarios. review does not intend to cover vast diversity literature published these subjects. Instead, authors strived overview scenario as central concept in many...
Multiple primary lung cancer (MPLC) is an increasingly prevalent subtype of cancer. According to recent genomic studies, the different lesions a single MPLC patient exhibit functional similarities that may reflect evolutionary convergence. We performed whole-exome sequencing for unique cohort patients with multiple samples from each lesion found. Using our own and other relevant public data, tree reconstruction revealed driver gene mutations occurred at early trunk, indicating contingency...
Abstract Phylogenetic estimations from 18S rDNA sequence data reveal close relationships of dioctophymids with Trichinellida (Trichocephalida), the latter represented by families Trichinellidae and Trichocephalidae (Trichuridae). This phylogeny is congruent a scenario molecular evolution deduced conservative motifs within V4 V9 regions rRNA. A phylogenetic approach to analyse containing highly unequal rates proposed. The entire gene possesses only few synapomorphies clade consisting...
A long recognized problem is the inference of supertree S that amalgamates a given set {G j } trees G , with leaves in each being assigned homologous elements. We ground on an approach to find tree by minimizing total cost mappings α individual gene into S. Traditionally, this defined basically as sum duplications and gaps . The classical minimize cost, where runs over all contain exhaustive non-redundant species from input suggest reformulation NP-hard building terms global minimization...
Abstract The phylum Nematoda remains very poorly sampled for mtDNA, with a strong bias toward parasitic, economically important or model species of the Chromadoria lineage. Most chromadorian mitogenomes share specific order genes encoded on one mtDNA strand. However, few sequenced representatives Dorylaimia lineage exhibit variable both strands. While ancestral arrangement nematode mitogenome undefined, no evidence has been reported Enoplia, phylum's third early divergent major We describe...
Abstract Parasitic life-strategies in the phylum Nematoda (roundworms) are remarkably diverse and intricate terms of evolution taxonomy. By analysing novel rDNA data obtained on rare host-associated groups with unusual biology, we reveal paraphyly last major taxon uncertain higher-rank classification that united solely parasitic nematodes (Marimermithida) to show primarily marine parasitism only emerged independently repeatedly a few free-living lineages. We report secondary seaward...