A5078870440- Lung Cancer Treatments and Mutations
- Lung Cancer Diagnosis and Treatment
- Gastric Cancer Management and Outcomes
- Abdominal Surgery and Complications
- Mycobacterium research and diagnosis
- Esophageal Cancer Research and Treatment
- Epigenetics and DNA Methylation
- Cancer Immunotherapy and Biomarkers
- Gut microbiota and health
- Toxoplasma gondii Research Studies
- Cancer Genomics and Diagnostics
- Herpesvirus Infections and Treatments
- Lung Cancer Research Studies
- Cytomegalovirus and herpesvirus research
- Genetic factors in colorectal cancer
Sun Yat-sen University
2021-2023
Fifth Affiliated Hospital of Sun Yat-sen University
2021-2023
Background: The characteristics and roles of microbes in the occurrence development pulmonary nodules are still unclear. Methods: We retrospectively analyzed microbial mNGS results BALF from 229 patients with before surgery, performed a comparative analysis lung flora between cancer benign according to postoperative pathology. also focused on investigating microbiota adenocarcinomas varying histopathology. Results: There were differences nodules. Bacterial diversity was lower than Four...
Multiple primary lung cancer (MPLC) is an increasingly prevalent subtype of cancer. According to recent genomic studies, the different lesions a single MPLC patient exhibit functional similarities that may reflect evolutionary convergence. We performed whole-exome sequencing for unique cohort patients with multiple samples from each lesion found. Using our own and other relevant public data, tree reconstruction revealed driver gene mutations occurred at early trunk, indicating contingency...
Cytomegalovirus (CMV) infection is a leading cause of morbidity and mortality after transplantation. This study aimed to investigate CMV seroprevalence, infection, disease in Chinese thoracic organ transplant recipients.The clinical data the patients who underwent lung and/or heart transplantation between January 2015 October 2020 were retrospectively collected from four centers China.A total 308 analyzed. The serostatus was donor positive (D+) recipient negative (R-) 19 (6.17%) patients,...
Abstract Objectives: This study aims to investigate the efficacy and safety of epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) as adjuvant therapy for resected non-small cell lung cancer (NSCLC) patients harboring EGFR mutations compared with chemotherapy or placebo, including latest updated data.Methods: A comprehensively systematic search relevant randomized controlled trials (RCTs) was performed. Hazard ratios (HRs) 95% confidence intervals (CI) were used analyse...
Abstract Background and Purpose We previously developed a new surgical method, namely, single-port inflatable mediastinoscopy simultaneous laparoscopic-assisted radical esophagectomy. The purpose of this study was to evaluate the effect carbon dioxide inflation on respiration circulation using approach. Methods From April 2018 October 2020, 105 patients underwent novel changes in respiratory circulatory functions were reported when mediastinal pressure pneumoperitoneum 10 12mmHg,...