Tim Klucken

ORCID: 0000-0003-2433-6652
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About
Contact & Profiles
Research Areas
  • Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
  • Stress Responses and Cortisol
  • Memory and Neural Mechanisms
  • Neural and Behavioral Psychology Studies
  • Neuroendocrine regulation and behavior
  • Mental Health Research Topics
  • Behavioral Health and Interventions
  • Sexuality, Behavior, and Technology
  • Digital Mental Health Interventions
  • Evolutionary Psychology and Human Behavior
  • Neurotransmitter Receptor Influence on Behavior
  • Olfactory and Sensory Function Studies
  • Child and Adolescent Psychosocial and Emotional Development
  • Neuroscience and Neuropharmacology Research
  • Smoking Behavior and Cessation
  • Virtual Reality Applications and Impacts
  • Impact of Technology on Adolescents
  • Tryptophan and brain disorders
  • Eating Disorders and Behaviors
  • Neural dynamics and brain function
  • Sexual function and dysfunction studies
  • Functional Brain Connectivity Studies
  • Psychosomatic Disorders and Their Treatments
  • Heart Rate Variability and Autonomic Control
  • Attachment and Relationship Dynamics

University of Siegen
2016-2025

Folkwang University of the Arts
2019-2024

Justus-Liebig-Universität Gießen
2011-2020

Ruhr University Bochum
2010-2011

In emotional learning tasks, sex differences, stress effects and an interaction of these two moderators have often been observed. The hormones estradiol (E2) progesterone (P4) vary over the menstrual cycle. We tested groups with different hormone status: 39 men, 30 women in luteal phase (LU, high E2+P4) 29 taking oral contraceptives (OC, low E2+P4). They received either mg cortisol or placebo prior to instructed differential fear conditioning consisting neutral conditioned stimuli (CS)...

10.1093/scan/nsr063 article EN cc-by-nc Social Cognitive and Affective Neuroscience 2011-10-11

Suicidal ideation is a major concern in clinical practice. Yet, little known about prevalence rates of suicidal patients undergoing outpatient psychotherapeutic treatment. Therefore, the aim current study to assess large sample psychotherapy outpatients Germany. The data analyzed this taken from KODAP-project on coordination collection and analysis at German university-based research training clinics for psychotherapy. A total N = 10,357 adult (64.4 % female; age: M(SD) 35.94 (13.54), range:...

10.1016/j.jad.2024.02.019 article EN cc-by-nc Journal of Affective Disorders 2024-02-10

In an fMRI study, effects of contingency awareness on conditioned responses were assessed in three groups comprising 118 subjects. A differential fear-conditioning paradigm with visual stimuli, electrical unconditioned stimulus and two distractors was applied. The instructed aware group informed about the contingencies, whereas prevented detection unaware group. third (learned aware) not but learned them despite distractors. Main emerged several brain structures. Post hoc tests revealed...

10.1093/scan/nsq070 article EN cc-by-nc Social Cognitive and Affective Neuroscience 2010-08-06

Gamification is often equipped with the promise to increase motivation and performance. However, research explaining which gamification design elements are effective mechanisms through these effects can be explained still at an early stage. By drawing on three psychological needs – competence, autonomy, social relatedness proposed by self-determination theory, we develop a model explain of feedback avatar reuse. We test 2 (avatar similarity: low vs. high) × (embodied feedback: no embodied...

10.1016/j.chb.2021.106702 article EN cc-by Computers in Human Behavior 2021-01-15

Fear extinction is a central model for the treatment of anxiety disorders. Initial research has reported that single presentation conditioned stimulus prior to learning can permanently block return fear. However, only few studies have explored this issue and could not always replicate findings. The present study examined human fear using four-day design. On first day, two neutral stimuli were paired with electrical stimulation (UCS), while third (CS−) was not. Twenty-four hours later, one...

10.1016/j.cortex.2016.03.015 article EN cc-by-nc-nd Cortex 2016-03-24

Practice-based evidence has emerged as an important complementary paradigm to studies in controlled trials. This paper presents results of a large research-practice network at German university outpatient clinics; the KODAP initiative. Pre-post effect sizes, direct assessments change, and rates clinically significant reliable improvement are reported heterogeneous clinical sample 6624 adult patients treated between 2023 2014 29 psychotherapeutic clinics. Clinical diagnoses, determined with...

10.1016/j.brat.2025.104691 article EN cc-by-nc Behaviour Research and Therapy 2025-01-23

Although meta-analyses suggest comparable efficacy of cognitive-behavioral therapy (CBT) in older adults compared to working-age adults, little is known about its effectiveness naturalistic settings across different age groups. Hence, this study symptom change, attrition rates, and treatment duration outpatient CBT between (18-64 years), young-old (65-74 old-old (≥ 75 years). We analyzed a large dataset comprising 9081 patients 18 96 years receiving Germany. Using propensity score matching,...

10.1016/j.jad.2025.01.145 article EN cc-by-nc Journal of Affective Disorders 2025-01-01

Abstract Background Tobacco use is globally recognized by the World Health Organization as foremost risk factor for premature mortality. Individuals with mental disorders exhibit a notably heightened dependence on tobacco, approximately twice high that of general population. The long-term effects nicotine consumption include an exacerbation depressive symptoms and decline in health, which can be considered additional factors vulnerable population smokers preexisting disorders. Successful...

10.1186/s13063-025-08781-2 article EN cc-by Trials 2025-03-03
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