- Schizophrenia research and treatment
- Mental Health and Psychiatry
- Mental Health Treatment and Access
- Child and Adolescent Psychosocial and Emotional Development
- Bipolar Disorder and Treatment
- Autoimmune and Inflammatory Disorders Research
- Obsessive-Compulsive Spectrum Disorders
- Rheumatoid Arthritis Research and Therapies
- Diet, Metabolism, and Disease
- Psychotherapy Techniques and Applications
- Eicosanoids and Hypertension Pharmacology
- Pharmaceutical studies and practices
- Innovative Teaching and Learning Methods
- Family Caregiving in Mental Illness
- Patient-Provider Communication in Healthcare
- Education and Technology Integration
- Teacher Education and Leadership Studies
- Healthcare Decision-Making and Restraints
- Family Support in Illness
- Parkinson's Disease Mechanisms and Treatments
- Spondyloarthritis Studies and Treatments
- Natural Antidiabetic Agents Studies
- Saffron Plant Research Studies
- Adolescent and Pediatric Healthcare
- Suicide and Self-Harm Studies
Douglas Mental Health University Institute
2016-2023
McGill University
2011-2023
Centre de Liaison Sur l'Intervention et la Prévention Psychosociales
2018-2019
Douglas College
2019
University of British Columbia
2009-2015
Jewish General Hospital
2012
This study aimed to determine if, following two years of early intervention service for first‐episode psychosis, three‐year extension that was superior three regular care. We conducted a randomized single blind clinical trial using an urn randomization balanced gender and substance abuse. Participants were recruited from clinics in Montreal. Patients (N=220), 18‐35 old, (EEIS; N=110) or care (N=110). EEIS included case management, family intervention, cognitive behaviour therapy crisis while...
One reason for worldwide interest in the clinical high-risk (CHR) state psychosis is its potential as a target prevention. However, feasibility and utility of early intervention initiatives that are focused on this stage involve an untested assumption: most patients with first episode (FEP) experience earlier CHR symptoms. The objective study was to identify characterize proportion FEP who had experienced such symptoms prior onset their psychosis.Semistructured interviews 351 families...
The early phases of psychosis, including the prodrome, often feature educational/occupational difficulties and various symptoms signs, that can render or keep youths "Not in Employment, Education Training" (NEET). Conversely, NEET status itself may increase risk for illness progression impaired functioning, impede access to appropriate services psychosis. As these issues have not been investigated, we aimed examine differences care pathways characteristics with psychosis who are...
<h3>Importance</h3> The clinical high-risk state in psychosis is most often characterized by subthreshold psychotic symptoms (STPS) and represents a target for prevention. However, evidence suggests that between 30% 50% of patients with first episode (FEP) report no prior history STPS, indicating not all FEP experience previous phase. As other early characteristics illness onset, this diversity the course may offer prognostic value subsequent trajectories. <h3>Objective</h3> To determine...
With previously established efficacy of aripiprazole once-monthly injectable formulation (AOM) in pre-registration randomized controlled trials, the current study was designed to evaluate its effectiveness patients treated for schizophrenia regular clinical settings Canada.Following their clinicians' decision prescribe AOM, 193 with a diagnosis schizophrenia, were recruited from 17 Canadian community or hospital-based settings. The primary outcome global functioning assessed Global...
Objective: Given the benefits of early intervention for psychosis and social disengagement youths not in education, employment, or training (NEET), this study sought to examine how being vocationally inactive (NEET) affects engagement services. Both baseline vocational status trajectory first year treatment were analyzed. Methods: Data from 394 patients a Canadian service analyzed using time-to-event Cox proportional hazards regression analyses. Two-year rates compared between who active at...
Abstract Background Specialized early intervention (EI) following a first episode of psychosis (FEP) are effective at reducing negative symptoms, although its trajectory warrants systematic assessment. However, findings equivocal as to whether extended gains made post 2 years EI and there is additional benefit extending for an 3 years. Methods Data on 178 FEP patients, from randomized controlled trial 3-year extension service v. transfer regular care service, were used this report. Repeated...
Abstract Objective Inflammatory arthritis is associated with a high degree of work instability and financial burden. In this study, we examine the extent loss as well their association disease characteristics during first 18 months inflammatory arthritis. Method One hundred four patients in early phase (more than 6 weeks, < months) were recruited from larger registry. Questionnaires recorded sociodemographic data characteristics, including pain assessed using S hort F orm M c G ill P ain...
Objective: We aimed to investigate whether individuals with first-episode psychosis (FEP) receiving extended early intervention (EI) were less likely experience suicidal ideation and behaviors than those transferred regular care after 2 years of EI. Another objective was examine the 5-year course suicidality in FEP. Methods: conducted a secondary analysis randomized controlled trial where 220 patients EI receive or for subsequent 3 years. Suicidality rated using Brief Psychiatric Rating...
The study objective was to examine whether and when antipsychotic-induced weight gain in first episode psychosis (FEP) stabilizes over a 12-month exposure the same antipsychotic sample of previously untreated FEP patients.In this prospective naturalistic outcome study, 109 patients diagnosed with non-affective or affective (DSM-IV) were treated medication (olanzapine n = 45, risperidone 39, aripiprazole 25) throughout year treatment. Body measured body mass index calculated at baseline 1, 2,...
Objective: Poor adherence to antipsychotic medications is strongly associated with psychotic relapses and hospitalizations. This may hinder patients’ ability function, particularly in a first episode of psychosis (FEP). treatment be due poor insight that can alter the capacity consent care, including pharmacotherapy. When patients are judged legally lacking mandated through community orders (CTOs). naturalistic study examines effects CTOs FEP patients. Method: 38 deemed unable care during...
<sec> <title>Introduction</title> Our study examines the association between disease characteristics of inflammatory arthritis and patients' self-perception mental health, parenting disability, stress child behaviour in early (EIA). </sec> <title>Methods</title> Patients phase (more than 6 weeks, less 18 months) were recruited from a larger EIA registry that recorded sociodemographic data measures pain, physical functioning activity. Patient-perceived stress, depression children's problems...
To investigate whether first-episode psychosis patients receiving extended early intervention had better functional outcomes than those in regular care and to examine the predictors of outcomes.This is a randomized controlled single-blind trial 220 after 2 years receive or for subsequent 3 years. Outcomes included cumulative time recovery during 3-year assessed using Social Occupational Functioning Assessment Scale (SOFAS); employment/education at last assessment which were, respectively,...
Cross-cultural psychosis research has typically focused on a limited number of outcomes (generally symptom-related). It is unknown if the purported superior for in some low- and middle-income countries extend to fundamental treatment processes like trust. Addressing this gap, we studied two similar first-episode programs Montreal, Canada Chennai, India. We hypothesized higher trust healthcare institutions providers among patients families Chennai at baseline over follow-up.
Individuals with mental health problems have many insufficiently met support needs. Across sociocultural contexts, various parties (e.g., governments, families, persons problems) assume responsibility for meeting these However, key stakeholders' opinions of the relative responsibilities needs remain largely unexplored. This is a critical knowledge gap, as perceptions may influence policy and caregiving decisions.
The literature emphasizes that the school environment is a key factor for mental health and academic achievementof immigrant refugee children. However, few studies examined role of peerrelationships these youth attending special education class. aim this paper to study associationbetween emotional difficulties performance their correlates in first second generationimmigrants assigned class multiethnic environment. results emphasize need adopt aneco-systemic model understand complex probably...
Objectives Most cross-cultural psychosis research has focused on a limited number of outcomes (generally symptom-related) and perspectives (often clinician-/observer-rated). It is unknown if the purported superior for in some low- middle-income countries extend to patient-reported measures social, recreational, independent functioning. Addressing this gap, study aimed compare these first-episode at high-income site lower site. Methods Patients receiving similarly designed early intervention...