A5028787219- Venous Thromboembolism Diagnosis and Management
- Blood Coagulation and Thrombosis Mechanisms
- Atrial Fibrillation Management and Outcomes
- Antiplatelet Therapy and Cardiovascular Diseases
- Blood properties and coagulation
- Multiple Myeloma Research and Treatments
- Cardiac Arrhythmias and Treatments
- Central Venous Catheters and Hemodialysis
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- COVID-19 Clinical Research Studies
- Cardiac pacing and defibrillation studies
- Hemophilia Treatment and Research
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Cancer Treatment and Pharmacology
- Diagnosis and Treatment of Venous Diseases
- SARS-CoV-2 and COVID-19 Research
- Vascular anomalies and interventions
- Blood groups and transfusion
- Cardiovascular Syncope and Autonomic Disorders
- Sepsis Diagnosis and Treatment
- Cerebral Venous Sinus Thrombosis
- Cardiac Arrest and Resuscitation
- Cytomegalovirus and herpesvirus research
- Apelin-related biomedical research
- Blood Pressure and Hypertension Studies
Northern Health
2016-2025
Australian Centre for HIV and Hepatitis Virology Research
2017-2025
Monash University
2018-2025
The University of Melbourne
2007-2025
Northern Hospital
2018-2024
Austin Hospital
2014-2024
Austin Health
2014-2023
The Alfred Hospital
2022
Sunway University
2021
Florey Institute of Neuroscience and Mental Health
2018-2019
Abstract Background Macroscopic fat pulmonary embolism is extremely uncommon. Most cases occur in the context of grafting or long bone fractures. may be associated with cardiopulmonary compromise and high mortality. Mechanical thrombectomy an emerging technique interventional radiology, primarily investigated as a therapeutic approach for thrombotic embolism. Case presentation We present case report 73-year-old woman macroscopic after neck femur fracture. Initially, she had severe...
Carrageenan-containing nasal sprays, available over-the-counter (OTC), are often marketed as having anti-viral effects. Carrageenan belongs to the glycosaminoglycan family alongside heparin, and heparin is known inhibit real-time quantitative polymerase chain reaction (RT-qPCR) in nasopharyngeal swabs used detect SARS-CoV-2. As carrageenan share structural similarities, this work aimed investigate interferent effect of on RT-qPCR for SARS-CoV-2 detection across 4 different diagnostic...
Increased tissue factor pathway inhibitor (TFPI) has been associated with cardiovascular disease (CVD). We aim to evaluate the predictive capability of TFPI for atherothrombotic events (ATE) in patients chronic kidney (CKD) and diabetes. A prospective observational study was performed at Northern Health, Australia. Patients CKD (estimated glomerular filtration ratio (eGFR) < 30 ml/min/1.73m2) and/or diabetes were recruited. Baseline total measured median follow-up 3.35 years. All egfr...
COVID-19 has rapidly evolved since it was first discovered in December 2019. We aimed to retrospectively review our experience with infection across 2020-2022, focusing on differences laboratory markers at presentation. Consecutive adult patients admitted hospital confirmed were reviewed three periods (29/3/2020-29/9/2020, 16/8/2021-13/10/2021 and 1/1/2022-31/1/2022), correlating the lineages B.1.338, Delta (B.1.617.2) Omicron (B.1.1.159), respectively. Laboratory findings of requested blood...
Abstract Context The thrombotic effects of estradiol therapy in transgender women are unclear. Global coagulation assays (GCA) may be better measures hemostatic function compared with standard tests. Objective To assess the GCA profiles comparison to cisgender controls and compare how differ between routes women. Design Cross-sectional case-control study. Setting General community. Participants Transgender women, male female controls. Main outcome Citrated blood samples were analyzed for (i)...
Abstract Background Clinical trials have demonstrated that direct oral anticoagulants (DOAC) are non‐inferior to vitamin K antagonist for stroke prevention in non‐valvular atrial fibrillation (AF) with comparable safety outcomes; however, real‐world Australian data limited. Aims To evaluate local DOAC use focussing on safety, particularly high‐risk patients. Methods A retrospective evaluation of 658 patients commenced or continued between September 2013 and 2016 AF at Northern Hospital, a...
Utilisation of low vision services remains in Australia. This study investigates service provision by optometrists Victoria and assesses the optometric human resource potential.An eight-item questionnaire was sent to 1,050 December 2006. It investigated key characteristics their practices, extent training influence Medicare item 10942 on provision.Although only 97 replies were received they represented a significant proportion who had undertaken postgraduate vision. Almost 86 per cent...
Deep vein thrombosis (DVT) frequently leads to post-thrombotic syndrome (PTS) which is challenging predict and prevent. Identifying those at high risk of developing PTS may help focus preventative strategies. Adults were recruited within 3 months DVT diagnosis. Blood was sampled during the therapeutic anticoagulation phase. Overall hemostatic potential (OHP) assay, a spectrophotometric performed on platelet-poor plasma (PPP). In this fibrin formation triggered by small amounts thrombin...
Venous thromboembolism (VTE) provoked by transient risk factors has traditionally been classified as a single entity with lower of recurrence. We evaluated the association between different categories provoking and relative recurrence.Retrospective evaluation VTE events in non-cancer patients from July 2011 to December 2012 at two tertiary institutions Australia minimum follow-up 24 months.A total 747 cases were identified, following exclusion mortality within 30 days presentation (n=26),...
: Myeloproliferative neoplasms (MPN) are independent risks for thrombotic events. Routine laboratory tests inadequate to evaluate the underlying procoagulant state. Global coagulation assays such as thromboelastography, thrombin and fibrin generation may provide better assessment of activation thereby thrombosis risk. Participants with MPN were recruited. Thromboelastography was performed on citrated whole blood while using calibrated automated thrombogram, overall haemostatic potential...