A5102708677- Parkinson's Disease Mechanisms and Treatments
- Neurological disorders and treatments
- Reconstructive Facial Surgery Techniques
- Breast Implant and Reconstruction
- Botulinum Toxin and Related Neurological Disorders
- Congenital Ear and Nasal Anomalies
- Reconstructive Surgery and Microvascular Techniques
- RNA regulation and disease
- Breast Cancer Treatment Studies
- Nasal Surgery and Airway Studies
California Northstate University
2025
University of California, Los Angeles
2021
The diagnosis of Parkinson's disease (PD) and atypical parkinsonian syndromes is difficult due to the lack reliable, easily accessible biomarkers. Multiple system atrophy (MSA) a synucleinopathy whose symptoms often overlap with PD. Exosomes isolated from blood by immunoprecipitation using CNS markers provide window into brain's biochemistry may assist in distinguishing between PD MSA. Thus, we asked whether α-synuclein (α-syn) such exosomes could distinguish among healthy individuals,...
Abstract Background Synucleinopathies are diseases characterized by aggregation and deposition of α‐synuclein in different brain cells. Diagnosis these neurological disorders is challenging due to overlapping complex clinical symptoms. Developing reliable biomarkers that can distinguish among the synucleinopathies an urgent public health need. Recently, was shown transfer via exosomes between cells suggesting measuring brain‐derived could serve as a potential biomarker for synucleinopathies....
Abstract Background Synucleinopathies are neurodegenerative diseases characterized by aggregation and deposition of α‐synuclein in different brain cells. Diagnosis these neurological disorders is very challenging due to overlapping complex clinical symptoms. Developing reliable biomarkers that can distinguish among the synucleinopathies an urgent public health need. Recently, was shown transfer via exosomes between cells suggesting measuring specific cell‐derived could serve as a potential...