- Lysosomal Storage Disorders Research
- Liver Disease Diagnosis and Treatment
- Helicobacter pylori-related gastroenterology studies
- Hepatitis B Virus Studies
- Gastroesophageal reflux and treatments
- Trace Elements in Health
- Hepatitis C virus research
- Eosinophilic Esophagitis
- Pediatric Hepatobiliary Diseases and Treatments
- Immunodeficiency and Autoimmune Disorders
- Carbohydrate Chemistry and Synthesis
- Glycogen Storage Diseases and Myoclonus
- Child Nutrition and Feeding Issues
- Liver Disease and Transplantation
- Infant Nutrition and Health
- Inflammatory Bowel Disease
- Gastrointestinal disorders and treatments
- Cellular transport and secretion
- Liver Diseases and Immunity
- Selenium in Biological Systems
- Hepatitis Viruses Studies and Epidemiology
- Heavy Metal Exposure and Toxicity
- Celiac Disease Research and Management
- Studies on Chitinases and Chitosanases
- Cystic Fibrosis Research Advances
Hacettepe University
2015-2025
Fırat University
2017-2024
Roche (Switzerland)
2023
Hacettepe University Hospital
1985-2021
Pediatrics and Genetics
2010
Boston Children's Hospital
2001-2004
University Gastroenterology
2001-2002
Children's Hospital
2001
May Institute
2000
Many screening methods, such as the Screening Tool Risk on Nutritional Status and Growth (STRONGkids) Pediatric Yorkhill Malnutrition Score (PYMS), have been developed to detect malnutrition in pediatric patients. We aimed explore prevalence of risk hospitalized children via symptoms identification contributing factors, examine efficacy tools for children.STRONGkids PYMS were applied 1513 inpatients at 37 hospitals 26 cities from different regions Turkey. Physical measurements collected...
Objective Use of peptide-based formulas supplemented with medium chain triglycerides (MCTs) is considered a beneficial strategy to decrease the tube-feeding associated gastrointestinal tolerance. In children cerebral palsy (CP), overall effects enteral tube feeding as well utility specialized in those intolerance have not been extensively studied. This study aimed evaluate via formula containing MCTs CP terms intolerance, anthropometrics, defecation characteristics and parental satisfaction...
Osteopenia is a common complication in adults with celiac disease. The effect of gluten-free diet on bone mineral density matter controversy. aim this study was to investigate children disease at diagnosis and patients treated for 1 year.Bone content were measured 34 untreated 28 year. results compared those 64 gender- age-matched healthy control subjects. Serum calcium, phosphate, alkaline phosphatase, 25 -hydroxy vitamin D, intact parathormone levels determined patients.The mean values...
The present paper aims to provide experts' consensus on diagnosis and management of cow's milk protein allergy (CMPA) among infants children in Turkey, based review available evidence-based guidelines, publications clinical experience. experts agreed that CMPA should be symptomatic evaluation diagnostic elimination diet as followed by implementation an open challenge test after disappearance symptoms confirmation re-appearance symptoms. For breastfed infants, differential involves withdrawal...
Helicobacter pylori infection is primarily acquired in childhood. However, the association between H. and recurrent abdominal pain (RAP) remains unclear.One hundred forty-one children with 21 without RAP underwent upper gastrointestinal endoscopy. At least five antral gastric biopsies were obtained from each patient presence of was accepted when at two out four tests (histology, direct smear, culture, rapid urease test) positive. Patients triple therapy omeprazole, clarithromycin,...
ABSTRACT Background. Helicobacter pylori infection is most frequently acquired in childhood. After this organism eradicated, the rate of reinfection low. Thus, it very important to diagnose and treat disease appropriately childhood, be able assess eradication with certainty. Eradication H. reported reduce or eliminate abdominal pain dyspeptic symptoms children. Patients Methods. The study involved 102 children who had already been diagnosed symptomatic based on gastric histopathological...
Background/Objectives: This study aims to identify genetic variants associated with early-onset inflammatory bowel disease (IBD) and improve diagnostic therapeutic approaches. In selected monogenic IBD cases, treatment included colchicine, interleukin-1 inhibitors, hematopoietic stem cell transplantation. Methods: patients IBD, defined as diagnosed before the age of 10, who were under follow-up at Department Pediatric Gastroenterology, Hacettepe University, agreed participate between...
We aimed to examine the frequency and characteristics of immunoglobulin G4 (IgG4)-associated autoimmune hepatitis among pediatric patients with hepatitis.Immunostaining for IgG IgG4 was performed in liver biopsies 40 hepatitis. The more than 10 IgG4-positive plasma cells/high-power field were defined as IgG4-associated Clinic, laboratory, histopathological results compared between groups.Among patients, 34 type 1 6 2 Six (15%), four two diagnosed Clinical, data initially similar both forms....
Niemann–Pick type C (NPC; OMIM 257219) disease is a neurodegenerative lysosomal storage disorder characterized by accumulation of unesterified cholesterol in the lysosomal/late endosomal system. This autosomal recessive occurs approximately 1/150,000 births. The broad clinical spectrum ranges from prenatal severe presentation to an adult-onset chronic disease. Data about NPC are limited. A female newborn was born at 342 weeks' gestation with birth weight 3070 g, and transferred Neonatal...