Nanotransporters: Self-assembled polymer multilayer nanorockets based on a template-assisted layer-by-layer technique can self-propel by chemical power, namely hydrogen peroxide degradation. They perform drug loading, targeted transportation, and triggered release an external physical stimuli in controlled manner. As service to our authors readers, this journal provides supporting information supplied the authors. Such materials are peer reviewed may be re-organized for online delivery, but...

We describe an approach to modulating the on-demand motion of catalytic polymer-based microengines via near-infrared (NIR) laser irradiation. The polymer multilayer motor was fabricated by template-assisted layer-by-layer assembly and subsequently deposition platinum nanoparticles inside a thin gold shell outside. Then mixed monolayer tumor-targeted peptide antifouling poly(ethylene glycol) functionalized on shell. remain motionless at critical peroxide concentration (0.1%, v/v); however,...

We demonstrate the first example of a self-propelled Janus polyelectrolyte multilayer hollow capsule that can serve as both autonomous motor and smart cargo. This new composed partially coated dendritic platinum nanoparticles (Pt NPs) was fabricated by using template-assisted layer-by-layer (LbL) self-assembly combined with microcontact printing method. The resulting motors still retain outstanding delivery capacities respond to external stimuli for controllable encapsulation triggered...

We present herein a novel hybrid, polymer-based motor that was fabricated by the template-assisted polyelectrolyte layer-by-layer (LbL) deposition of thin gold layer on one side, followed chemical immobilization catalytic enzyme. Such Janus capsule motors can self-propel at 0.1% peroxide fuel concentration physiological temperature and have higher speed as compared to Pt-based synthetic motors. They were exploited for encapsulation chemotherapeutic anticancer drug, doxorubicin, navigation...

A self-assembled three-dimensional hierarchical porous V₂O₅/graphene hybrid aerogel for high-performance supercapacitor was synthesized.

Inspired by the dynamics of bacterial swarming, we report a swarm polymer-brush-grafted, glucose-oxidase-powered Janus gold nanoswimmers with positive, macroscale chemotactic behavior. These are prepared through grafting polymer brushes onto one side nanoparticles, followed functionalization glucose oxidase on other side. The resulting polymer-brush-functionalized exhibit efficient propulsion velocity up to approximately 120 body lengths s-1 in presence glucose. comparative analysis their...

Three-dimensional V₂O₅/MWCNT core/shell hybrid aerogels were controllably synthesized through a mixed growth and self-assembly methodology in one-pot sol–gel process.

Abstract We report a thermoresponsive poly( N ‐isopropylacrylamide) (PNIPAM) brush functionalized Janus Au–Pt bimetallic micromotor capable of modulating the direction motion with change ambient temperature. The PNIPAM@Au–Pt moved along speed 8.5 μm s −1 in 1.5 % H 2 O at 25 °C (below lower critical solution temperature (LCST) PNIPAM), whereas it changed (i.e., Pt–Au direction) and decreased to 2.3 35 (above LCST). Below LCST, PNIPAM brushes grafted on Au side were hydrophilic swelled, which...

Abstract We report a direct experimental observation of the torque‐driven active reorientation glucose‐fueled flasklike colloidal motors to glucose gradient exhibiting positive chemotaxis. These streamlined are prepared by combining hydrothermal synthesis and vacuum infusion can be propelled an enzymatic cascade reaction in fuel. Their architecture used recognize their moving posture, thus dynamic glucose‐gradient‐induced alignment orientation‐dependent motility during chemotaxis examined...

This review has focused on the up-to-date development of targeted drug delivery systems to GBM, with specific emphasis utilization nanorobotic for active targeting.

We report a hollow dumbbell-shaped manganese dioxide (MnO2) colloidal kayaker capable of converting pair breathing oxygen bubbles into self-propelled movement. The bubble generated by catalytic decomposition hydrogen peroxide fuel grew either synchronously or asynchronously, driving the to move along fluctuating circle. synchronous asynchronous mode is governed asymmetric sites kayakers. This imbalanced distribution propulsion force generates and centripetal on kayaker. dynamics kayakers...

Various nanoplatforms have been developed to visualize intracellular microRNAs (miRNAs) because of their clinical significance in tumor progression and diagnosis. However, the diffusion-limited motion penalizes miRNA imaging efficiency cells. Herein, we fabricated a near-infrared (NIR) light-propelled Janus-based nanoplatform advance response. The Janus nanomotor covered with an Au half-shell was loaded by endocytosis adjuvant MnO2 nanosheet for delivering miRNA-responsive hQN (hairpin DNA...

Cells orchestrate the motion and force of hundreds protein motors to perform various mechanical tasks over multiple length scales. However, engineering active biomimetic materials from that consume energy propel continuous micrometer-sized assembling systems remains challenging. Here, we report rotary biomolecular motor-powered supramolecular (RBMS) colloidal are hierarchically assembled a purified chromatophore membrane containing FOF1-ATP synthase molecular motors, an polyelectrolyte...

The use of a near-infrared (NIR) laser for reversible modulation bubble-driven Janus polymer capsule motor is demonstrated. This process was mediated through illumination the metal face at critical concentration peroxide fuel. Such an effective control propulsion chemically powered microengines holds considerable promise diverse applications.

We report multiscale structured fibers and patterned films based on a semiconducting polymer, poly(3-hexylthiophene) (P3HT), as photoconductive biointerfaces to promote neuronal stimulation upon light irradiation. The micro/nanoscale structures of P3HT used for interfacing include nanofibers with an average diameter 100 nm, microfibers about 1 μm, lithographically stripes width 3, 25, 50 respectively. effect irradiation provides electrical differentiation directed growth. Our results...

Peptides are widely used within biomaterials to improve cell adhesion, incorporate bioactive ligands, and enable cell-mediated degradation of the matrix. While many peptides incorporated into intended be present throughout life material, their stability is not typically quantified during culture. In this work, we designed a series peptide libraries containing four different N-terminal functionalizations three C-terminal better understand how simple modifications can reduce nonspecific...

Nanotransporter: Selbstorganisierte Mehrschichtpolymer-Nanoraketen, die nach einem Templatansatz schichtweise aufgebaut wurden, können sich aus eigenem Antrieb fortbewegen. Die Energie dafür beziehen sie der Zersetzung von Wasserstoffperoxid. Strukturen Wirkstoffe aufnehmen, transportieren und auf externe physikalische Reize hin kontrolliert freisetzen.

Laminar blood flow represents the normal physiological state of circulation, but it also acts as a natural barrier for effective diffusion drugs to lesion site. Here, we report bioinspired strategy in which reconfigurable vortexlike swarms magnetic swimming nanobots actively disrupt laminar deliver manner similar how bacteria seek food. The drug was released from cavity biodegradable, submicron pentosan flask-like nanobots, aggregates dynamic rotating fluid under field. nanobot swarm...