A5101767885- Viral gastroenteritis research and epidemiology
- Animal Virus Infections Studies
- Viral Infections and Immunology Research
- Fungal Biology and Applications
- Bacteriophages and microbial interactions
- Fungal and yeast genetics research
- Fermentation and Sensory Analysis
- Winter Sports Injuries and Performance
- Plant and fungal interactions
- Pulmonary Hypertension Research and Treatments
- Thyroid Cancer Diagnosis and Treatment
- Neural Networks and Applications
- Mesenchymal stem cell research
- Saffron Plant Research Studies
- Viral-associated cancers and disorders
- Plant and Fungal Interactions Research
- Head and Neck Anomalies
- Plant Virus Research Studies
- Pediatric health and respiratory diseases
- Cytomegalovirus and herpesvirus research
- Animal Disease Management and Epidemiology
- Hepatitis Viruses Studies and Epidemiology
- Respiratory and Cough-Related Research
- Microbial Natural Products and Biosynthesis
- Diabetic Foot Ulcer Assessment and Management
National University of Defense Technology
2025
Hebei University of Engineering
2021-2024
Guizhou Academy of Agricultural Sciences
2019-2024
Yantaishan Hospital
2022-2024
Jinzhou Medical University
2022
Shihezi University
2020
Chinese Academy of Agricultural Sciences
2014-2018
Harbin Veterinary Research Institute
2014-2018
Putian University
2008
Hospital of Hebei Province
2006
As a prevalent agent in cats, feline herpesvirus 1 (FHV-1) infection contributes to respiratory disease and acute chronic conjunctivitis. FHV-1 can successfully evade the host innate immune response persist for lifetime of cat. Several mechanisms evasion by human herpesviruses have been elucidated, but mechanism remains unknown. In this study, we screened open reading frames (ORFs) responsible inhibiting type I interferon (IFN) pathway with an IFN-β promoter reporter analysis mRNA levels HEK...
This study aimed to evaluate the miR-223-5p expression in patients with spinal cord injury (SCI) and determine its role pathogenesis of SCI.
Background: Operations for pediatric thyroid nodules are more complicated, and usually lead to longer scars, which may impair life quality in the long term. Bilateral axillo-breast approach robotic thyroidectomy (BABA RT) provide a better alternative conventional open (COT) nodules. Our study aimed at comparing surgical oncological outcomes of BABA RT COT patients. Methods: The data 49 patients who consecutively underwent or (20:29) between July 1998 November 2021 our center were...
Feline Calicivirus (FCV) infection results in the inhibition of host protein synthesis, known as “shut-off”. However, precise mechanism shut-off remains unknown. Here, we found that FCV strain 2280 proteinase-polymerase (PP) can suppress luciferase reporter gene expression driven by endogenous and exogenous promoters. Furthermore, N-terminal 263 aa PP (PPN-263) determined its activity using truncated proteins. same domain F9 failed to inhibit expression. A comparison between strains...
Interferons (IFNs) can inhibit most, if not all, viral infections by eliciting the transcription of hundreds interferon-stimulated genes (ISGs). Feline calicivirus (FCV) is a highly contagious pathogen cats and surrogate for Norwalk virus. Interferon efficiently inhibits replication FCV, but mechanism antiviral activity poorly understood. Here, we evaluated anti-FCV ten ISGs, whose activities were previously reported. The results showed that interferon regulatory factor 1 (IRF1)...
To replicate efficiently and evade the antiviral immune response of host, some viruses degrade host mRNA to induce gene shutoff via encoding factors. In this study, we found that feline calicivirus (FCV) infection promotes degradation endogenous exogenous mRNAs induces shutoff, which results in global inhibition protein synthesis. Screening assays revealed proteinase-polymerase (PP) is a most effective factor reducing expression. Moreover, PP from differently virulent strains FCV could...
Abstract Shiraia bambusicola is a rare medicinal fungus found in China that causes bamboo plants to decay and die with severe infection. Hypocrellin, its main active ingredient, widely used several fields, such as medicine, agriculture, food industry. In this study, clarify the genomic components, taxonomic status, pathogenic genes, secondary metabolite synthesis pathways, regulatory mechanisms of S. bambusicola, whole-genome sequencing, assembly, functional annotation were performed using...
ABSTRACT Here, we report the complete genome sequence of feline calicivirus (FCV) strain HRB-SS isolated in 2014 from a cat Heilongjiang Province northeastern China. The virus is 7,705 bases, excluding poly(A) tail. This analysis will help to understand genetic characteristics and evolution FCV
ABSTRACT Aspergillus cristatus is a dominant fungus formed during the “flowering” process of Fuzhuan brick tea. Previous research has established that sporulation nidulans , model organism filamentous fungi, regulated by light. However, A. dependent on osmotic stress. In previous study, we used pull‐down and mass spectrometry to identify proteins interacted with AcHog1 in when cultured under different conditions present analyzed identified previously investigate their functional role. The...
A highly efficient method for the detection and quantification of 55 veterinary antibiotics (VAs) in chicken manure belonging to six drug classes using solid-phase extraction (SPE) ultrahigh-performance liquid chromatography–tandem mass spectrometry (UPLC–MS/MS) was developed. The mixture EDTA–McIlvaine buffer (pH 3.0) organic extractant (methanol–acetonitrile, 1:3, v/v) used isolate target VAs from freeze-dried manure. extract purified by a hydrophile–lipophile balance cartridge. All showed...
Feline calicivirus (FCV) is a highly contagious pathogen seriously affecting the upper respiratory tract and producing oral diseases in feline. Despite widespread vaccination, prevalence of FCV remains high. In this study, qingdao (qd)/2019/china was isolated from domestic feline oropharyngeal swab collected Qingdao, China. The virus purified using plaque assay identified Polymerase chain reaction indirect immunofluorescence methods, capsid amino acid,
Pulmonary hypertension is called PH for short. It caused by the pulmonary artery vascular disease leading to resistance, and increase right lung compartment load, which resulting in weakening or even collapse of ventricular function. The establishment rat model under action monocrotaline a repeatable, simple accessible operation technique, has been widely used treatment hypertension. This paper discusses principle properties on rats action.
Ewing sarcoma is the second most common primary malignant bone tumor in pediatrics after osteosarcoma, which mainly occurs children and adolescents aged 5-20 y. Crocin main active ingredient extracted from Crocus sativus has significant inhibitory effect on many cancer cells. Therefore, this study observed of crocin human its specific mechanism provided molecular theoretical basis for clinical application. We cultured Human cells lines SK- ES-1 RD-ES vitro treated them with 0, 2.5, 5 10...
Filamentous fungi reproduce sexually or asexually, and the developmental processes are strictly regulated by a variety of transcription factors. In this study, we characterized zinc finger factor, called AcrpnR, in Aspergillus cristatus (GME2916). The ∆AcrpnR strain exhibited decreased asexual reproduction increased cleistothecium production. complementation showed restoration these phenotypic differences. Overexpression AcrpnR resulted enhanced development delayed inhibited sexual...
Abstract Feline calicivirus (FCV) is a highly contagious pathogen that can cause seriously upper respiratory tract and oral disease in feline. Despite widespread vaccination, the prevalence of FCV remains high. In this study, qd/2019/china was isolated from domestic feline oropharyngeal swab which collected qingdao, China. The virus purified with plaque assay identified PCR IFA method. capsid amino acid ,VP1, [1] showed sequence identity other isolate ranging 83.9% (ym3/2001/jp) to 91.1%...