- Nanoplatforms for cancer theranostics
- Nanoparticle-Based Drug Delivery
- Photodynamic Therapy Research Studies
- Nanoparticles: synthesis and applications
- Advanced Nanomaterials in Catalysis
- Phytochemicals and Medicinal Plants
- Graphene and Nanomaterials Applications
- Photoacoustic and Ultrasonic Imaging
- Phytochemicals and Antioxidant Activities
- Polymer-Based Agricultural Enhancements
- Essential Oils and Antimicrobial Activity
- Scientific and Engineering Research Topics
- Cancer Research and Treatments
- Adipokines, Inflammation, and Metabolic Diseases
- High Entropy Alloys Studies
- Hibiscus Plant Research Studies
- Protein Hydrolysis and Bioactive Peptides
- Laser-Ablation Synthesis of Nanoparticles
- Plant Growth Enhancement Techniques
- Cancer, Hypoxia, and Metabolism
- Infant Nutrition and Health
- Advanced biosensing and bioanalysis techniques
- High-Temperature Coating Behaviors
- RNA Interference and Gene Delivery
- Cancer, Stress, Anesthesia, and Immune Response
Indian Institute of Technology Hyderabad
2022-2025
Indian Institute of Technology Kanpur
2023
The heterogenicity of TNBC can be tackled by casein-based nanosystem with high therapeutic efficacy.
Abstract Photothermal therapy (PTT) and photodynamic (PDT) have been emerging as potential alternatives to conventional cancer treatment modalities. Gold nanoparticles, owing their surface plasmon resonance properties, promising in phototherapies, extracts from potentially medicinal plants are commonly employed for the green synthesis of various nanoparticles. Some researchers also using chlorophyll photosensitizer reactive oxygen species (ROS) generation. In this research, photothermal...
Photothermal/photodynamic therapies (PTT/PDT) are multimodal approaches employing near-infrared (NIR) light-responsive photosensitizers for cancer treatment. In the current study, IR-775, a hydrophobic photosensitizer, was used in combination with polyphenols (p)-rich ethyl acetate extract from Terminalia chebula to treat cancer. IR-775 dye and were encapsulated poly(lactic acid) polymeric nanosystem (PpIR NPs) increase cell bioavailability. The hydrodynamic diameter of PpIR NPs is 142.6 ± 2...
With the advent of nucleosome/nucleotide intercalating drugs, DNA-based nanocarriers have recently gained impetus. However, most newly proposed DNA nanosystems are rather complex, thereby having low scalability and translatability. In this study, we propose a simple nanomatrix core encapsulated within chitosan shell, which is expected to enhance encapsulation efficiency drugs. This has been demonstrated using proflavine hemisulfate (PfHS), model agent that shows improved ROS generation,...
Abstract The potential use of antioxidants for photodynamic therapy (PDT) is investigated in this study. PDT causes reactive oxygen species (ROS)-mediated cell death; on the contrary, scavenge ROS. a photosensitizer along with an antioxidant compensates loss ROS due to antioxidant, eventually leading death. In work, and photothermal (PTT), we have combined IR 792 perchlorate dye alpha-tocopherol (A) p -coumaric acid (C) encapsulated polymeric nanocarrier (AC NPs). We reported synthesis AC...
Nano-biofertilizers are the biologically synthesized nano-fertilizers from microbes and plants employed in agricultural fields to promote crop production protection. For instance, specifically, plant growth-promoting (PGPM) having significant growth promotion antagonistic traits, have led their wide range of applications as nano-biofertilizers. In scenario, soil, crops, microbiome nano-biofertilizers often influence one another ecological systems. The application these PGPM promised enhanced...
Abstract Diabetic wounds are a significant complication of diabetes that is characterized by delayed wound healing and high risk amputation. The overexpression pro‐inflammatory macrophages (M1) matrix metallo protease‐9 (MMP‐9) plays crucial role in the extended inflammatory phase, which characteristic these wounds. This study develops multifunctional lipid nanoemulsions known as Quercetin Rosemary Oil Lipid Nanoemulsions (Q‐RLNEs) can effectively convert M1 to M2 macrophages, inhibit MMP‐9...
In the current research, dye-embedded polylactic acid (PLA) conjugate materials were synthesized using one-pot ring-opening polymerization (ROP), i.e., (dtHP
Human respiratory diseases caused by viral infections leads to morbidity. Among infectious diseases, associated with the tract remain primary reason for global deaths due their transmissibility. Since immemorial, traditional Indian medicinal plants, extracts, and several phytochemicals can treat various diseases. Sources this review paper are data derived from a peer-reviewed journal that emphasizes economic importance of plants. Several plant-based medicines have been reported be effective...
PTT has shown promising target cancer therapy and been able to achieve high cell death rates while rescuing normal tissue. In this article, IR-775 a less explored hydrophobic photosensitizer was used in combination with polyphenols for the treatment of cancer. The nanosystem consists HSPC, PLA, dye constituents from Terminalia chebula. lipopolymeric HP pIR NPs (HSPC-PLA-polyphenols extract-IR775) exhibit size range (142.6 ± 2nm). have excellent intracellular uptake when studied against A549...