A5025775492- Medical Imaging Techniques and Applications
- Radiomics and Machine Learning in Medical Imaging
- Advanced X-ray and CT Imaging
- Radiation Detection and Scintillator Technologies
- Advanced MRI Techniques and Applications
- Advanced Radiotherapy Techniques
- Asthma and respiratory diseases
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Ion-surface interactions and analysis
- Electron and X-Ray Spectroscopy Techniques
- Glioma Diagnosis and Treatment
- Cancer, Hypoxia, and Metabolism
- Coronary Interventions and Diagnostics
- Renal and related cancers
- Radiopharmaceutical Chemistry and Applications
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Advanced Neuroimaging Techniques and Applications
- Air Quality and Health Impacts
- Lung Cancer Diagnosis and Treatment
- Electronic Health Records Systems
- Cardiac Imaging and Diagnostics
- Head and Neck Cancer Studies
- Advanced Electron Microscopy Techniques and Applications
- Ear and Head Tumors
- Bone Tumor Diagnosis and Treatments
Hitachi (Japan)
2012-2023
Hokkaido University
2022
Nara Medical University
2022
Tohoku Medical and Pharmaceutical University
2019-2021
Suwa Red Cross Hospital
2021
Ikeda Municipal Hospital
2020
Nagano Prefectural College
2016
Okayama University of Science
2007-2009
Hosei University
2002
Tottori University
1982-1988
Artificial intelligence (AI), including predictive analytics, has great potential to improve the care of common chronic conditions with high morbidity and mortality. However, there are still many challenges achieving this vision. The goal project was develop apply methods for enhancing disease using AI.
To establish an enterprise initiative for improving health and care through interoperable electronic record (EHR) innovations.We developed a unifying mission vision, established multidisciplinary governance, formulated strategic plan. Key elements of our strategy include establishing world-class team; creating shared infrastructure to support individual innovations; developing implementing innovations with high anticipated impact clear path adoption; incorporating best practices such as the...
Targeting improved spatial resolution, a three-dimensional positron-emission-tomography (PET) scanner employing CdTe semiconductor detectors and using depth-of-interaction (DOI) information was developed, its physical performance evaluated. This PET is the first to use dedicated human brain head-and-neck region. Imaging of used for <formula formulatype="inline" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"><tex Notation="TeX">$^{18}{\rm F}$</tex>...
An autoradiography method revealed intratumoral inhomogeneity in various solid tumors. It is becoming increasingly important to estimate inhomogeneity. However, with low spatial resolution and high scatter noise, it difficult detect clinical settings. We developed a new PET system CdTe semiconductor detectors provide images noise. Both phantom patients9 were analyzed evaluate <b>Methods:</b> This study was performed cold spot that had 6-mm-diameter sphenoid defects, dual-cylinder an adjusted...
For high-sensitivity brain imaging, we have developed a two-head single-photon emission computed tomography (SPECT) system using CdTe semiconductor detector and 4-pixel matched collimator (4-PMC). The term, '4-PMC' indicates that the hole size is to 2 × array of pixels. By contrast, 1-pixel (1-PMC) defined as whose one pixel. performance higher-sensitivity 4-PMC was experimentally compared with 1-PMC. sensitivities 1-PMC were 70 cps/MBq/head 220 cps/MBq/head, respectively. SPECT provides...
Background Airflow limitation is a critical physiological feature in chronic obstructive pulmonary disease (COPD), for which long-term exposure to noxious substances, including tobacco smoke, an established risk. However, not all smokers develop COPD, meaning that other risk factors exist. Objective This study aimed predict the COPD diagnosis using machine learning annual medical check-up database. Methods In this retrospective observational cohort (ARTDECO [Analysis of Risk Factors Detect...
The red nucleus (RN) is a pair of small gray matter structures located in the midbrain and involved muscle movement cognitive functions. This retrospective study aimed to investigate metabolism human RN its correlation other brain regions.We developed high-resolution semiconductor PET system image structures. Twenty patients without neurologic disorders underwent whole-brain scanning after injection 400 MBq (18)F-FDG. individual (18)F-FDG images were spatially normalized generate surface...
Pulmonary tumor thrombotic microangiopathy (PTTM) is a fatal cancer-related pulmonary complication. It generally caused by gastric adenocarcinoma, and several molecules produced cells are reported to play important roles in its pathogenesis. We herein report an autopsy case of PTTM urothelial carcinoma. Vascular endothelial growth factor (VEGF), platelet-derived (PDGF), osteopontin were found be expressed both the primary metastatic lesions. These findings implicate possible involvement...
We propose a wide aperture parallel-hole collimator that we call 4-pixel matched (4-PMC) for high-sensitivity SPECT imaging. The hole size of the 4-PMC is to four detector pixels; is, there are (2 × 2) pixels per hole. By contrast, 1-pixel (1-PMC) defined as whose one pixel. evaluated types (high-resolution versions and both 1-PMC) by simulation. images cylindrical phantom with cold spots in noise-free condition demonstrated provided higher-contrast image than 1-PMC same version. In...
Hypoxic cancer cells are thought to be radioresistant and could impact local recurrence after radiotherapy (RT). One of the major hypoxic imaging modalities is [18F]fluoromisonidazole positron emission tomography (FMISO-PET). High FMISO uptake before RT indicate sites might associated with future recurrence. The predictive value FMISO-PET for intra-tumoral regions was evaluated using high-resolution semiconductor detectors in patients nasopharyngeal carcinoma intensity-modulated (IMRT).Nine...
Electronic health record (EHR) data are increasingly used to develop prediction models support clinical care, including the care of patients with common chronic conditions. A key challenge for individual healthcare systems in developing such is that they may not be able achieve desired degree robustness using only their own data. potential solution—combining from multiple sources—faces barriers as need normalization and concerns about sharing patient information across institutions. To...
A brain single-photon emission computed tomography (SPECT) system using cadmium telluride (CdTe) solid-state detectors was previously developed. This CdTe-SPECT is suitable for simultaneous dual-radionuclide imaging due to its fine energy resolution (6.6 %). However, the problems of down-scatter and low-energy tail spectral characteristics a pixelated detector should be addressed. The objective this work develop Tc-99m I-123 studies evaluate accuracy.A scatter correction method five windows...
A Monte Carlo (MC)-based scatter correction method considering the tailing effect of a CdTe detector was developed for dual-isotope brain single-photon emission computed tomography (SPECT) imaging using technetium-99m (99mTc) and iodine-123 (123I), its accuracy validated by measuring phantoms. The modeled convolutions energy spectra obtained geometry tracking (GEANT) simulation with smoothing kernels. In our experimental phantom studies, quantitative image contrast in reconstructed...
We developed a prototype 3D PET scanner that uses CdTe semiconductor detectors. The is dedicated to human brain imaging. A detector should have advantages when used as (e.g. good quantitative imaging and high-spatial resolution). detectors incorporate three important technical features: stacked crystals, no contact with the board, direct soldering onto board. Our comprises 18 units 350-mm-diameter patient port has transaxial field of view 310 mm an axial 250 mm. demonstrated had timing...
Vision-based moving in formation by four mobile robots is presented. One robot who a leader and goes first provides plans to the other follow leading robot. These move not only single line, but also triangular or diamond formation. Each detects means of color image classification using three-layer neural network. In motion control, radial basis function (RBF) network approximated learning used. addition, hardware implementations results demonstration how multiple several formations are...
We developed a prototype CdTe SPECT system with 4-pixel matched collimator for brain study. This provides high-energy-resolution (6.6%), high-sensitivity (220 cps/MBq/head), and high-spatial-resolution images. The aim of this study was to evaluate dual-isotope CBF central benzodiazepine receptor (BZR) images using Tc-ECD I-IMZ the new in patients epilepsy comparing single-isotope conventional scintillation gamma camera.This included 13 partial epilepsy. BZR were acquired at 3 hours after...