A5102739235- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Microwave Imaging and Scattering Analysis
- Advanced SAR Imaging Techniques
- Asymmetric Synthesis and Catalysis
- Geophysical Methods and Applications
- Crystallography and molecular interactions
- Bioinformatics and Genomic Networks
- Radar Systems and Signal Processing
- Catalytic C–H Functionalization Methods
- Gene expression and cancer classification
- Axial and Atropisomeric Chirality Synthesis
- Silicone and Siloxane Chemistry
- Advanced Battery Technologies Research
- Chemical synthesis and alkaloids
- Advanced biosensing and bioanalysis techniques
- Seismic Imaging and Inversion Techniques
- Atrial Fibrillation Management and Outcomes
- Aerogels and thermal insulation
- Oxidative Organic Chemistry Reactions
- Seismic Waves and Analysis
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Machine Learning in Bioinformatics
- Underwater Acoustics Research
- Advanced Synthetic Organic Chemistry
Wuhan University
2025
Guangxi Normal University
2024-2025
China Pharmaceutical University
2025
Beijing Anzhen Hospital
2025
Capital Medical University
2025
Fujian Agriculture and Forestry University
2025
Shanghai Normal University
2024
China Southern Power Grid (China)
2024
Zhejiang University
2023
State Key Laboratory of Modern Optical Instruments
2023
Essential proteins play an essential role in cell survival and replication. Currently, more computational methods are developed to identify proteins, which overcome the time-consuming, costly inefficient shortcomings with biological experimental methods.In order improve recognition rate, some new by fusing multiple features developed, but they seldom consider connection among features. After analyzing a large number of based on multi-feature fusion, phenomenon is found, called weak...
The ultra-wideband (UWB) multi-input multi-output (MIMO) radar technique is playing a more and important role in the application of through-wall detection because its high resolution, lower antenna requirements, efficient data capturing ability. This paper develops novel UWB MIMO system using stepped-frequency continuous-wave (SFCW) signal, which designed to detect human targets behind regular brick concrete wall. In order balance range resolution wall-penetration depth, miniaturized Vivaldi...
Abstract Background The associations between left atrial (LA) size, echocardiographic diastolic parameter (E/A ratio), and incident fibrillation (AF) in older inpatients remain underexplored. Aims This study aimed to evaluate the relationship LA E/A ratio, AF risk hospitalized patients. Methods Between January 2015 May 2023, a total of 2,615 (aged ≥ 65 years) were enrolled this retrospective longitudinal study. Left diameter (LAD) ratio measured using transthoracic echocardiography. Results...
Accurate and efficient assessment of highland barley (Hordeum vulgare L.) density is crucial for optimizing cultivation management practices. However, challenges such as overlapping spikes in unmanned aerial vehicle (UAV) images the computational requirements high-resolution image analysis hinder real-time detection capabilities. To address these issues, this study proposes an improved lightweight YOLOv5 model spike detection. We chose depthwise separable convolution (DSConv) ghost...
Cancer as a public health problem is driven by genomic variations in 'cancer driver' genes. The identification of driver genes critical for the discovery key biomarkers and development personalized therapy. We propose prediction method MNMO: multi-layer network model based on multi-omics data. MNMO firstly constructs dynamically adjusted four-layer composed miRNAs three kinds with different features. Then scores, ie, control capacity, mutation score, are devised calculated harmonic mean to...
A novel metal-free catalytic annulation was developed through a Lewis base-catalyzed asymmetric allylic alkylation and the ensuing unprecedented intramolecular acylcyanation of alkenes. This protocol provides unique facile access to prepare enantioenriched densely functionalized dihydronaphthoquinones accompanied by enantiomerically pure 3,3-disubstituted phthalides bearing quaternary carbon centers.
Cancer is a complex genomic mutation disease, and identifying cancer driver genes promotes the development of targeted drugs personalized therapies. The current computational method takes less consideration relationship among features effect noise in protein-protein interaction(PPI) data, resulting low recognition rate. In this paper, we propose identification based on dynamic incentive model, DIM. This firstly constructs hypergraph to reduce impact false positive data PPI. Then, importance...
The conjugate addition of cyclic 1,3-dicarbonyl compounds to β,γ-unsaturated α-keto-esters was studied using a series chiral bifunctional organocatalysts.Takemoto's catalyst found be most efficient for this transformation.Excellent yields and good enantioselectivities were achieved variety compounds.A catalytic mechanism is proposed.The method provides new asymmetric synthetic route courmarin derivatives.
A new probe/Cu2+ complex for the detection of his-tagged protein has been developed, based on an improved probe, Dansyl-Gly-Py (1), by closely mimicing structure a peptide, ATCUN. In aqueous solution, 1/Cu2+ good selectivity to histidine and cysteine, further can detect histidine-rich releasing quenched fluorescence 1.
A novel asymmetric synthetic approach for the construction of enantioenriched functionalized dihydroquinones incorporating adjacent quaternary and tertiary stereocenters has been reported, in which 3-allylic phthalides engaged an unprecedented sulfa-Michael addition-triggered stereoselective ring-expansion reaction, furnished desired sulfur-incoporated dihydronaphthoquinones with high stereoselectivity.
Free space optical communication (FSO) has gained significant attention due to the growing demand for a high information capacity. For FSO between multiple or moving targets, receiver with wide angle of acquisition capability is necessary. Traditionally, gimbals and fast steering mirrors have been used, but they are often difficult make both compact wide-angle. Here, novel duplex system demonstrated, which utilizes highly fiber coupling metalens receive transmit signals in large field view...
Abstract The integration of dual asymmetric catalysis is highly beneficial for the synthesis organic molecules with multiple stereocenters. However, two major issues that need to be addressed are intrinsic deactivation dual-species and extrinsic conflict reaction conditions. To overcome these concerns, we have utilized compartmental thermoresponsive properties poly( N -isopropylacrylamide) (PNIPAM) develop a cross-linked PNIPAM-hydrogel-supported bifunctional catalyst. This catalyst designed...
The conjugate addition of aldehydes and ketones to 3-nitro-2H-chromenes under basic conditions has been explored.A series inorganic organic bases were examined.Proline combined with NaOAc was found act as an efficient catalyst for the reaction.A number substituted 3-nitro-2H-chromenes, aldehydes, are applicable this transformation.trans-3-Nitro-4-substituted chromanes sometimes obtained in good yields excellent diastereoselectivities. trans-2- propanal could be transformed into...
In the present study, protective effects of myricitrin against vascular endothelial growth factor (VEGF)-induced angiogenesis cells were characterized. Cells induced with 50 ng/mL VEGF in presence or absence various concentrations for 24 h. Myricitrin treatment significantly reduced cell proliferation by more than %. treated showed increased caspase 3/7 activity and apoptosis a dose-dependent manner. Treatment 1, 10, 100 μM matrix metalloproteinase (MMP) 23.3 %, 46.2 64.3 respectively. MMP1...