A5073590261- Microbial Metabolic Engineering and Bioproduction
- Enzyme Catalysis and Immobilization
- Neuroinflammation and Neurodegeneration Mechanisms
- Extraction and Separation Processes
- Alzheimer's disease research and treatments
- Biofuel production and bioconversion
- Molecular Sensors and Ion Detection
- Inhalation and Respiratory Drug Delivery
- Long-Term Effects of COVID-19
- Immune Response and Inflammation
- Electrochemical sensors and biosensors
- Protein Hydrolysis and Bioactive Peptides
- Biochemical effects in animals
- Nanoparticle-Based Drug Delivery
- Computational Drug Discovery Methods
- Enzyme Production and Characterization
- Metal complexes synthesis and properties
- Protein Interaction Studies and Fluorescence Analysis
- Process Optimization and Integration
- Business and Economic Development
- COVID-19 Clinical Research Studies
- Bacterial biofilms and quorum sensing
- Innovative Microfluidic and Catalytic Techniques Innovation
- COVID-19 and Mental Health
- Inorganic and Organometallic Chemistry
GD Goenka University
2021
Delhi Technological University
2019-2021
University of Delhi
1988-2005
Indian Institute of Technology Delhi
2000-2001
Aim: This study was aimed at evaluating the anticancer potential of curcumin-loaded poly(lactic-co-glycolic acid) (PLGA) based nanoparticles (NPs) in MDA-MB231 human breast cancer cells. Methods: Curcumin-loaded PLGA NPs were developed using a modified solvent evaporation technique. Physical characterization performed on formulated NPs. Furthermore, vitro experiments conducted to biological activity Results: demonstrated high encapsulation efficiency and sustained payload release. Moreover,...
Aim: Statistical medium optimization for maximum production of a hyperthermostable lipase from Burkholderia cepacia and its validation in bioreactor. Methods Results: was grown shake flasks containing 1% glucose, 0·1% KH2PO4, 0·5% NH4Cl, 0·24% (NH4)2HPO4, 0·01% MgSO4.7H2O emulsified palm oil, at 45 °C pH 7·0, agitated 250 rev min−1 with 6‐h‐old inoculum (2% v/v) 20 h. A fourfold enhancement (50 U ml−1) an approximately three fold increase specific activity (160 mg−1) by B. obtained 14 litre...
Abstract Batch propionic acid fermentation kinetics was studied using five different initial concentrations of lactose (i.e., 37 g/L, 45g/L, 50g/L, 57 g/L and 73 g/L) at constant temperature (30°C) pH (6.5) under anaerobic conditions Propionibacterium acidipropionici (ATCC 4875). When the substrate concentration 45 50 then, correspondingly, 16 19 22.25 25.3 26.3 accumulated in broth. Increasing supply medium led to accumulation by products succinate, acetate pyruvate. Maximum propionate...
Objective: In-silico methods to find and characterize the ligands against active site of tau protein which could assist in therapeutics Alzheimer's disease. Methods: The aid various bioinformatic tools such as phylogenetic analysis, homology modeling, prediction led molecular docking analysis major malefactor for Alzheimer’s disease ‘microtubule- associated protein’. A three-dimensional structure microtubule-related was created, Ramachandran plot acquired quality appraisal. Results: Procheck...
Abstract Several organomercury(II) complexes of the type RHgL1(I), RHgL2(II) and RHgClL3 (III) [HL1 = 6-aminopenicillinic acid, HL2 theophylline, L3 isoniazid; R p-chlorophenyl(p-ClC6H4), p-bromophenyl(p-BrC6H4)] have been synthesized characterised. Conductance measurements reveal that are non-electrolytes. The bonding modes ligands to metal ion has determined from IR UV spectral studies. 1H NMR data confirms stoichiometry complexes.