A5091833950- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Inflammatory Bowel Disease
- Crystallography and molecular interactions
- Particle accelerators and beam dynamics
- Genetic and phenotypic traits in livestock
- Magnetic confinement fusion research
- Microscopic Colitis
- Biofuel production and bioconversion
- Superconducting Materials and Applications
- Reproductive System and Pregnancy
- Microbial Metabolic Engineering and Bioproduction
- Viral gastroenteritis research and epidemiology
- Gut microbiota and health
- Livestock Management and Performance Improvement
- Enzyme Production and Characterization
- Algal biology and biofuel production
- Reproductive Physiology in Livestock
- Functional Brain Connectivity Studies
- Advanced Neuroimaging Techniques and Applications
- Phytase and its Applications
- Superconductivity in MgB2 and Alloys
- Agricultural Economics and Practices
- Thermal Expansion and Ionic Conductivity
- Clostridium difficile and Clostridium perfringens research
Pfizer (United States)
2025
Institute for Plasma Research
2001-2025
Adaptive Biotechnologies (United States)
2024-2025
Guru Jambheshwar University of Science and Technology
2015-2024
Satguru Partap Singh Hospital
2024
University of New Mexico
2021-2024
Central Agricultural University
2024
University of Trinidad and Tobago
2024
Christian Medical College
2009-2023
All India Institute of Medical Sciences Bhubaneswar
2023
Patients who are immunocompromised (IC) at increased risk of Clostridium difficile infection (CDI), which has to epidemic proportions over the past decade. Fecal microbiota transplantation (FMT) appears effective for treatment CDI, although there is concern that IC patients may be having adverse events (AEs) related FMT. This study describes multicenter experience FMT in patients.A retrospective series was performed on use with CDI recurrent, refractory, or severe. We aimed describe rates...
Ten monoclones directed to the 42,000-dalton inner structural protein of rotavirus were analyzed. Eight reacted broadly with antigenic domains common virtually all mammalian rotaviruses. Two had specificities similar or identical previously characterized subgroup specificities. These more efficient in detecting antigen than either hyperimmune postinfection antisera. Using monoclones, we determined that some animal as well human strains carry 2 specificity and epizootic diarrhea infant mice...
Crohn's disease (CD) is a chronic idiopathic inflammatory intestinal disorder associated with fecal dysbiosis. Fecal microbial transplant (FMT) potential therapeutic option for individuals CD based on the hypothesis that changing dysbiosis could promote less inflammation.Nine patients, aged 12 to 19 years, mild-to-moderate symptoms defined by Pediatric Disease Activity Index (PCDAI of 10-29) were enrolled into prospective open-label study FMT in (FDA IND 14942). Patients received nasogastric...
Microbes may increase susceptibility to inflammatory bowel disease (IBD) by producing bioactive metabolites that affect immune activity and epithelial function. We undertook a family based study identify microbial metabolic features of IBD represent predisease risk state when found in healthy first-degree relatives.Twenty-one families with pediatric were recruited, comprising 26 Crohn's patients clinical remission, 10 ulcerative colitis 54 siblings/parents. Fecal samples collected for 16S...
Low infliximab (IFX) trough levels and high anti-infliximab antibodies (ATI) are associated with loss of response to IFX. Optimizing IFX maintain target concentrations before may improve long-term efficacy. We hypothesized that at week 14 predictive durability.A prospective observational cohort pediatric patients inflammatory bowel disease initiating had ATI drawn weeks 54. Primary outcome was 54 persistent remission (PR), defined as clinical without dose intensification. Univariate analyses...
Though vedolizumab has received regulatory approval for the treatment of Crohn's disease (CD) and ulcerative colitis (UC) in adults, there is increasing off-label use children.To describe experience with pediatric inflammatory bowel (IBD) patients at 3 tertiary IBD centers examine predictors remission.A retrospective review identified (age < 18 yrs) receiving vedolizumab. Data on demographics, behavior, location, activity, previous treatments/surgeries were collected. Disease activity was...
In recent years, it has been well documented that gut flora not only influence mosquito physiology, but also significantly alter vector competency. Although, salivary gland and constitute key partners of the digestive system, is still believed glands may harbor less than (Parasit Vectors 6: 146, 2013). Using a metagenomic approach, we have identified for first time diverse microbial community associated with these two physiologically different tissues system in Anopheles culicifacies. A...
ABSTRACT Background: Ulcerative colitis (UC), a chronic inflammatory disease of the large intestine, is characterized by dysregulated immune reaction. UC associated with fecal dysbiosis. Human and animal studies support fact that gastrointestinal microbiome may trigger intestinal response, resulting in UC. Fecal microbial transplantation (FMT), changing patients UC, be therapeutic option. Methods: Four moderate symptoms defined Pediatric Colitis Activity Index were enrolled prospective,...
Pain syndromes of Guillain-Barré are neuropathic as well nociceptive in origin. We aimed to evaluate the therapeutic efficacy gabapentin relieving bimodal nature pain syndrome a randomized, double-blinded, placebo-controlled, crossover study 18 patients admitted intensive care unit for ventilatory support. Patients were assigned receive either (15 mg · kg−1 d−1 3 divided doses) or matching placebo initial medication 7 days. After 2-day washout period, those who previously received placebo,...
Wastewater remediation is of paramount importance for the water-stressed modern civilization from perspective sustainable development and management limited freshwater resources. Contaminants such as heavy metal metalloid ions, toxic dyes, pathogenic microbes present in aquatic ecosystem have adverse effects not only on environment but also human health. Traditional wastewater processes are costly, energy-consuming, less efficiency removing pollutants wastewater. Multi-phasic nanomaterials...