- Neuroscience of respiration and sleep
- Neonatal Respiratory Health Research
- Restraint-Related Deaths
- Infant Health and Development
- Child and Adolescent Health
- Grief, Bereavement, and Mental Health
- Infant Development and Preterm Care
- Injury Epidemiology and Prevention
- Congenital Diaphragmatic Hernia Studies
- Homelessness and Social Issues
- Neonatal and fetal brain pathology
- COVID-19 and healthcare impacts
- Emergency and Acute Care Studies
- COVID-19 Impact on Reproduction
- Respiratory Support and Mechanisms
- Neonatal Health and Biochemistry
- Breastfeeding Practices and Influences
- Sleep and related disorders
- Heart Rate Variability and Autonomic Control
- Autopsy Techniques and Outcomes
- Sleep and Wakefulness Research
- Migration, Health and Trauma
- Influenza Virus Research Studies
- Childhood Cancer Survivors' Quality of Life
- Smoking Behavior and Cessation
St Michael's Hospital
1996-2025
University of Bristol
2016-2025
University of Hull
2020-2024
Institute of Child Health
1990-2021
Bristol Regional Medical Center
2019
St Michaels Hospital
1995-2016
North Yorkshire County Council
2012-2014
St. Michael's Hospital
1995-2014
Eastern Virginia Medical School
2011
St Michael’s Hospital
1996-2008
BackgroundThe Confidential Inquiry into premature deaths of people with intellectual disabilities in England was commissioned to provide evidence about contributory factors avoidable and this population.MethodsThe population-based reviewed the aged 4 years older who had been registered a general practitioner one five Primary Care Trust areas southwest England, died between June 1, 2010, May 31, 2012. A network health, social-care, voluntary-sector services; community contacts; statutory...
<h3>Abstract</h3> <b>Objective</b>: To investigate the role of sleeping arrangements as risk factors for sudden infant death syndrome after a national reduction campaign. <b>Design</b>: Two year population based case-control study. Parental interviews were conducted each who died and four controls matched age date interview. <b>Setting</b>: Three regions in England with total 17 million people. <b>Subjects</b>: 195 babies 780 controls. <b>Results</b>: Prone side positions both carried...
<b><i>Objective:</i></b> Therapeutic hypothermia (HT) is the standard treatment for newborns after perinatal asphyxia. Preclinical studies report that HT more effective when started early. <b><i>Methods:</i></b> Eighty cooled were analyzed and grouped according to cooling was birth: early (≤180 min) or late (>181 min). For survivors we whether starting associated with a better psychomotor mental developmental index (PDI MDI, Bayley Scales of...
<h3>Abstract</h3> <b>Objective</b>: To investigate the effects of exposure to tobacco smoke and parental consumption alcohol illegal drugs as risk factors for sudden infant death syndrome after a national reduction campaign which included advice on prenatal postnatal avoidance smoke. <b>Design</b>: Two year population based case-control study. Parental interviews were conducted each who died four controls matched age date interview. <b>Setting</b>: Three regions in England with total 17...
<b>Objectives</b> To investigate the factors associated with sudden infant death syndrome (SIDS) from birth to age 2 years, whether recent advice has been followed, any new risk have emerged, and specific circumstances in which SIDS occurs while cosleeping (infant sharing same bed or sofa an adult child). <b>Design</b> Four year population based case-control study. Parents were interviewed shortly after reference sleep (within 24 hours) of two control groups. <b>Setting</b> South west region...
To provide reference data on sleep duration throughout childhood and explore the demographic characteristics associated with sleep.Population-based prospective longitudinal birth-cohort study.South-West England, children born in 1991-1992 followed since birth.Eleven thousand five hundred repeat measures of from birth based parent-reported questionnaires. Data daytime nighttime timings night awakenings at 8 timepoints age 6 months to 11 years.Total steadily fell 13 hours 12 minutes during...
Objective The risk of sudden infant death syndrome (SIDS) among infants who co-sleep in the absence hazardous circumstances is unclear and needs to be quantified. Design Combined individual-analysis two population-based case-control studies SIDS controls comparable for age time last sleep. Setting Parents 400 1386 provided information from five English health regions between 1993–6 (population: 17.7 million) one these 2003–6 (population:4.9 million). Results Over a third (36%) were found...
<h3>Objective</h3> To investigate longitudinal sleep patterns in children with autistic spectrum disorders (ASDs). <h3>Study design</h3> Prospective study using Avon Longitudinal Study of Parents and Children, an English cohort born 1991–1992. Parental reports duration were collected by questionnaires at 8 time points from 6 months to 11 years. Children ASD diagnosis age years (n=73) identified health education records. <h3>Results</h3> From aged 30 old, slept for 17–43 min less each day...
Importance England has one of the highest infant mortality rates in Europe. Much variation between races and ethnicities may be due to socioeconomic factors, but how deprivation race ethnicity are associated with is unclear. Objectives To investigate association rate England, adjusted for preterm birth level deprivation. Design, Setting, Participants This cohort study included children who died younger than 1 year age, born at or after 22 weeks’ gestation, occurring from April 1, 2019, March...
Objectives. To establish whether epidemiologic characteristics for sudden infant death syndrome (SIDS) have changed since the decrease in rate after “Back to Sleep” campaign 1991, and compare these with unexpected deaths infancy (SUDI) from explained causes. Design. Three-year, population-based, case-control study. Parental interviews were conducted soon 4 controls matched age date of interview. All included study cause was established by a multidisciplinary panel relevant health care...
OBJECTIVE--To examine the impact of changing practice with regard to infant sleeping position on mortality from sudden death syndrome. DESIGN--A population based study all infants dying suddenly and unexpectedly during February 1990 July 1991, two groups controls; one comprising every 125th baby born Avon residents other pairs matched each index case for age, neighbourhood, date study. Information about was collected at home visits soon after baby9s or, controls, several occasions in first...
Congenital central hypoventilation (Ondine's curse) is described in an infant with persistant symptoms throughout the first nine months of life. Respiratory control was most severely affected quiet sleep, although abnormalities were present rapid eye movement (REM) sleep and while awake. Failure metabolic led to profound hypoventilation. Behavioral or "behavioral-like" inputs awake state REM increased ventilation, but not expected normal levels. The ventilatory response inhaled 4% CO2...
Twenty-four hour recordings of respiratory wave form and ECG were made on low-birth-weight and/or premature infants within one week discharge from eight neonatal intensive care units. Eight (0.7%) had episodes apnea greater than 30 seconds in duration, all which accompanied by bradycardia less 100 beats per minute; 25 (2.3%) a total 36 apneic between 20 29 or equal to 19 (1.7%) 50 minute without prolonged (as shown lack breathing movement). Five ventricular (including with tachycardia)....
Serial respiratory recordings using impedance pneumography and barometric plethysmography were made from shortly after birth to 7 months in fifteen normal full‐term infants. Each recording was with the infant asleep sleep state estimated records of electroencephalogram electro‐oculogram parallel. The obtained during non‐rapid eye movement (r.e.m.) analysed computer assistance stretches record, approximately 1 min before up 2 a spontaneous sigh ensuing apnoeic pause, processed presented as...
OBJECTIVES: This is an investigation into the longitudinal patterns of bed sharing, characteristics associated with those patterns, and relationship breastfeeding. METHODS: The study used prospective, population-based data from United Kingdom to investigate nocturnal sharing at 5 time points birth 4 years age. Of 14 062 live births, 7447 (53%) had available for all points. RESULTS: Latent class analysis identified mutually exclusive groups, broadly described as nonsharers (66%), early...
Summary Associations between sleep duration and disturbance in infancy early childhood attention deficit hyperactivity disorder diagnoses were investigated. Data from the Avon Longitudinal Study of Parents Children, a population‐based prospective longitudinal birth‐cohort study children born 1991–1992 South‐West England, employed. Eight thousand, one hundred ninety‐five assessed using Development Well‐Being Assessment. One seventy‐three cases (2.1%) met criteria for disorder. Parental report...