Yufei Chen

ORCID: 0000-0003-2523-5896
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About
Contact & Profiles
Research Areas
  • Thyroid and Parathyroid Surgery
  • Adrenal and Paraganglionic Tumors
  • Thyroid Cancer Diagnosis and Treatment
  • Pituitary Gland Disorders and Treatments
  • Hormonal Regulation and Hypertension
  • Cancer, Hypoxia, and Metabolism
  • Diet and metabolism studies
  • Airway Management and Intubation Techniques
  • Global Cancer Incidence and Screening
  • Head and Neck Anomalies
  • Gastric Cancer Management and Outcomes
  • Voice and Speech Disorders
  • BRCA gene mutations in cancer
  • Parathyroid Disorders and Treatments
  • Cardiac pacing and defibrillation studies
  • Hip and Femur Fractures
  • Artificial Intelligence in Healthcare and Education
  • Art Therapy and Mental Health
  • Retinoids in leukemia and cellular processes
  • Bariatric Surgery and Outcomes
  • Hormonal and reproductive studies
  • Radiomics and Machine Learning in Medical Imaging
  • Pediatric Pain Management Techniques
  • Genital Health and Disease
  • Cardiac Arrhythmias and Treatments

Cedars-Sinai Medical Center
2019-2025

Hubei University of Medicine
2024-2025

Hangzhou Women’s Hospital
2025

Pfizer (United States)
2025

Shanghai Jiao Tong University
2021-2024

Ruijin Hospital
2021-2024

Fudan University
2020-2024

Hong Kong Jockey Club
2023-2024

Chinese University of Hong Kong
2023-2024

First Affiliated Hospital of Zhengzhou University
2023-2024

BACKGROUND Well‐differentiated thyroid cancer (WDTC) is a prevalent disease, which increasing in incidence faster than any other cancer. Substantial direct medical care costs are related to the diagnosis and treatment of newly diagnosed patients as well ongoing surveillance who have long life expectancy. Prior analyses aggregate health attributable WDTC United States not been reported. METHODS A stacked cohort cost analysis was performed on US population from 1985 2013 estimate number...

10.1002/cncr.28562 article EN Cancer 2014-01-30

Laparoscopic adrenalectomy is the gold standard for most adrenal disorders and its frequency in United States increasing. While national administrative databases can adjust patient factors, comorbidities, institutional variations, granular disease-specific data that may significantly influence incidence of perioperative complications length stay (LOS) are lacking.

10.1001/jamasurg.2018.2648 article EN JAMA Surgery 2018-08-08

<h3>Importance</h3> While well-differentiated papillary thyroid carcinoma (WDPTC) outcomes have been well characterized, the prognostic implications of more aggressive variants are far less defined. The rarity these subtypes has led to their consolidation as intermediate risk for what in fact likely heterogeneous diseases. <h3>Objective</h3> To analyze incidence, clinicopathologic characteristics, and (PTC). <h3>Design, Setting, Participants</h3> This cohort study used data from 2000 2016...

10.1001/jamaoncol.2019.6851 article EN JAMA Oncology 2020-03-05

Calorie restriction plus dietary advice is suggested as a preventive strategy for individuals with obesity and prediabetes; however, optimal diet still debatable. We aimed to compare the effects of Mediterranean (MD) Chinese diets high or low in plants on body weight glucose homeostasis among high-risk Chinese.In this parallel-arm randomized controlled trial, 253 adults aged 25 60 years mass index ≥ 24.0 kg/m2 fasting blood 5.6 mmol/L were randomly assigned 3 isocaloric-restricted diets: MD...

10.1210/clinem/dgac303 article EN cc-by-nc-nd The Journal of Clinical Endocrinology & Metabolism 2022-05-17

Objective: To explore a new artificial intelligence (AI)-aided method to assist the clinical diagnosis of femoral intertrochanteric fracture (FIF), and further compare performance with human level confirm effect feasibility AI algorithm. Methods: 700 X-rays FIF were collected labeled by two senior orthopedic physicians set up database, 643 for training database 57 test database. A Faster-RCNN algorithm was applied be trained detect on X-rays. The such as accuracy, sensitivity, miss rate,...

10.3389/fbioe.2022.927926 article EN cc-by Frontiers in Bioengineering and Biotechnology 2022-09-06

Objective: This study tested the efficacy of Acceptance and Commitment Therapy (ACT), compared with Cognitive–Behavioral (CBT), in alleviating academic procrastination. Method: A total 60 (53.3% male) undergraduates suffering from procrastination were randomly assigned to two treatment groups (ACT CBT) a control group. The symptoms related psychological mechanisms assessed immediately after closure at 3-month follow-up (FU). Results: Both therapies showed remarkable short-term effects...

10.1177/1049731515577890 article EN Research on Social Work Practice 2015-04-02

Carotenoids are well-established for their potent antioxidant properties; however, potential association with severe headaches or migraines remains largely unexamined. This study was conducted to explore the relationship between serum carotenoid levels and prevalence of within US population. We utilized data from 2001-2004 National Health Nutrition Examination Survey (NHANES), which comprised a total 8,910 participants. Serum levels-specifically α-carotene, β-carotene, β-cryptoxanthin,...

10.3389/fnut.2024.1507503 article EN cc-by Frontiers in Nutrition 2025-01-06

Postoperative outcomes of patients with normotensive pheochromocytomas are poorly documented. We aimed to evaluate the impact preoperative hypertension on post-operative following adrenalectomy for pheochromocytoma. An international retrospective study undergoing pheochromocytoma in 46 centers between 2012-2022 was performed. Hypertensive and were defined respectively by presence or absence history before at time diagnosis. To differences postoperative hypertensive patients, propensity score...

10.1210/clinem/dgaf154 article EN cc-by The Journal of Clinical Endocrinology & Metabolism 2025-03-06

Abstract Objective To evaluate the efficacy of different periods for prevention postoperative nausea and vomiting (PONV) in patients undergoing gynecological laparoscopy with transcutaneous electrical acupoint stimulation (TEAS). Design Prospective, randomized, double-blind trial. Setting An academic medical canter specializing care women children. Population or sample A total 120 were enrolled. Methods Patients randomly allocated to three groups: a single-period TEAS group (Group S, n =...

10.1186/s12906-025-04847-5 article EN cc-by BMC Complementary Medicine and Therapies 2025-03-20

Abstract Chronic and dysregulated inflammation caused by activation of interleukin-1 (IL-1) signaling supports tumor growth helps establish an immunosuppressive microenvironment. Interleukin 1 receptor accessory protein (IL1RAP, IL-1RAcP, IL1R3) serves as a co-receptor for interleukin type (IL1R1) at the cell membrane plays key role in mediating IL-1 signaling. By combining multi-omics immunohistochemistry analysis, we identified upregulation IL1RAP on many solid indications, including...

10.1158/1538-7445.am2025-4253 article EN Cancer Research 2025-04-21

Abstract Background Remote access and endoscopic thyroid surgery has been gaining popularity because it allows patients to avoid a visible scar in the neck. There is limited data on transoral thyroidectomy when relates with papillary carcinoma. We aim evaluate safety of ipsilateral central compartment dissection for who undergo (thyroidectomy vestibular approach–compartment lymph node dissection). Patients Methods A total 80 underwent carcinoma from June 2015 September 2016 were identified....

10.1093/jjco/hyz195 article EN Japanese Journal of Clinical Oncology 2019-12-12

Background: Active surveillance is established as an alternative to surgery for papillary thyroid microcarcinomas, but inclusion criteria and mortality risk pursuing a nonsurgical approach have not been clearly defined. To gauge the feasibility of expanding active thresholds, we investigated effects increasing size age on disease-specific survival (DSS) in large nonoperative cancer cohort, compared against matched group surgical patients. Methods: Papillary carcinoma patients staged T1-4N0M0...

10.1089/thy.2019.0060 article EN Thyroid 2019-08-13

To provide complementary information and reveal the molecular characteristics therapeutic insights of HER2-low breast cancer, we performed this multiomics study hormone receptor-negative (HR-) also known as triple-negative cancer (TNBC), identified 3 subgroups: basal-like, receptor tyrosine kinase-relevant (TKR), mesenchymal stem-like. These subgroups had distinct features potential targets were validated in external data sets. Interestingly, TKR subgroup (which exists both HR+ HR- cancer)...

10.1172/jci.insight.172366 article EN cc-by JCI Insight 2023-11-21

The efficacy of multitarget neuroprotective drug DL-3-n-butylphthalide (NBP) in improving cognitive function has been confirmed patients with vascular impairment without dementia. However, its symptomatic predementia phase Alzheimer's disease remains uncertain. This study aims to evaluate the and safety NBP mild (MCI) through a clinical randomised controlled trail.

10.1136/bmjopen-2023-082404 article EN cc-by-nc BMJ Open 2024-07-01

10.1245/s10434-025-16869-x article EN Annals of Surgical Oncology 2025-01-26

Minimally invasive and remote access thyroid surgery has been evolving with the transoral endoscopic thyroidectomy vestibular approach (TOETVA) emerging as a true "scarless" thyroidectomy. In this study, we describe hybrid submental (TOaST) technique for lobectomy.A TOaST right lobectomy was performed 4 cm cytologically benign nodule. Initial incision made in region two additional 5 mm lateral ports inserted transorally. Right proceeded via standard TOETVA intact specimen extraction...

10.1089/lap.2018.0146 article EN Journal of Laparoendoscopic & Advanced Surgical Techniques 2018-05-07

Background: While numerous factors determine prognosis in papillary thyroid carcinoma (PTC), distant metastasis (M1) represents one of the most dire. Escalating nodal burden and aggressive histology may contribute to higher metastatic risk, but this relationship is poorly defined challenging anticipate. We evaluate predictive impact these histological features on predicting metastases at initial presentation. Methods: Univariate multivariable logistic regression models conventional cancer...

10.1089/thy.2021.0131 article EN Thyroid 2021-09-02
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