A5090826678- Cancer Genomics and Diagnostics
- Heat shock proteins research
- Gastric Cancer Management and Outcomes
- RNA Research and Splicing
- Sirtuins and Resveratrol in Medicine
- Radiomics and Machine Learning in Medical Imaging
Xuzhou Medical College
2022
Affiliated Hospital of Qingdao University
2019
Qingdao University
2019
Systemic peripheral blood mononuclear cell (PBMC) humanized model is a straightforward tool to evaluate therapeutic immuno-oncology (IO) drugs, including immune checkpoint blockers (ICB) and bispecific antibodies (BsAb). However, the has limited dosing regimen window due graft-versus-host disease (GVHD), as seen in most deficient recipients. There also relative lower responsible rate from insufficient antigen specific cells infiltration into tumor microenvironment (TME). Thus, application of...
Sortilin 1 (SORT1) has been reported as an oncogene in several human tumors. Nonetheless, the biological functions of SORT1 hepatocellular carcinoma (HCC) remain poorly understood.Western blotting was employed for determination protein expression. Hepatocellular cell viability, apoptosis, migration, and invasion were measured via CCK-8, flow cytometry, wound healing, Transwell assays.Sortilin upregulated HCC closely associated with unsatisfactory outcomes patients. Furthermore, vitro vivo...
<sec> <title>BACKGROUND</title> With the increasingly abundant of cancer treatment, emergence multidisciplinary team (MDT) will provide patients with personalized treatment options. In recent years, artificial intelligence has developed rapidly in medical field. And there is a tendency to replace traditional diagnosis and gradually. IBM Watson for Oncology (WFO) been proven breast lung cancer, but research on gastric rarely so far. </sec> <title>OBJECTIVE</title> Compared concordance WFO...