A5084391265- Gastric Cancer Management and Outcomes
- Enhanced Recovery After Surgery
- Metastasis and carcinoma case studies
- Gastrointestinal Tumor Research and Treatment
- Nutrition and Health in Aging
- Colorectal Cancer Surgical Treatments
- Hepatocellular Carcinoma Treatment and Prognosis
- Cancer-related molecular mechanisms research
- Liver Disease Diagnosis and Treatment
- Radiomics and Machine Learning in Medical Imaging
- Liver Disease and Transplantation
- MicroRNA in disease regulation
- Pancreatic and Hepatic Oncology Research
- Frailty in Older Adults
- Esophageal and GI Pathology
- Advanced Radiotherapy Techniques
- Organ Transplantation Techniques and Outcomes
- RNA modifications and cancer
- Glycosylation and Glycoproteins Research
- Cardiac, Anesthesia and Surgical Outcomes
- Cancer Mechanisms and Therapy
- Cancer Immunotherapy and Biomarkers
- Renal cell carcinoma treatment
- Ovarian cancer diagnosis and treatment
- Cholangiocarcinoma and Gallbladder Cancer Studies
Qingdao University
2019-2025
Affiliated Hospital of Qingdao University
2019-2025
China Medical University
2016-2024
First Hospital of China Medical University
2016-2024
Data Management (Italy)
2021-2024
Northeastern University
2024
Wuhan Polytechnic University
2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2018-2023
Shandong University of Traditional Chinese Medicine
2023
General Hospital of Shenyang Military Region
2020
Abstract Aim The present study aimed to assess the benefits of two-stent techniques for patients with DEFINITION criteria-defined complex coronary bifurcation lesions. Methods and results In total, 653 lesions at 49 international centres were randomly assigned undergo systematic technique (two-stent group) or provisional stenting (provisional group). primary endpoint was composite target lesion failure (TLF) 1-year follow-up, including cardiac death, vessel myocardial infarction (TVMI),...
Objective: A large-scale multicenter retrospective cohort study was conducted to compare the short- and long-term outcomes of robotic gastrectomy (RG) laparoscopic (LG) for gastric cancer. Summary Background Data: RG is being increasingly used worldwide, but data from studies on oncologic versus LG are limited. The potential benefits compared with cancer remain controversial. Methods: Data eligible patients who underwent or 11 experienced surgeons 7 centers in China between March 2010...
Abstract The heterogeneous nature of tumors presents a considerable obstacle in addressing imatinib resistance advanced cases gastrointestinal stromal (GIST). To address this issue, we conducted single-cell RNA-sequencing primary as well peritoneal and liver metastases from patients diagnosed with locally or GIST. Single-cell transcriptomic signatures tumor microenvironment (TME) were analyzed. Immunohistochemistry multiplex immunofluorescence staining used to further validate it. This...
Transjugular intrahepatic portosystemic shunt (TIPS) is a standard treatment option for the management of portal hypertension in liver cirrhosis. Since introduction covered stents, patency has been greatly improved. However, it remains uncertain about whether stents could improve survival. A meta-analysis randomized controlled trials performed to compare outcomes versus bare TIPS.PubMed, EMBASE, and Cochrane Library databases were searched identify relevant trials. Overall survival, patency,...
Purpose: Transcutaneous electrical acupoint stimulation (TEAS) is an innovative choice for postoperative pain management. However, the safety and effectiveness of this traditional Chinese medicine (TCM) therapy patients who underwent gastrectomy largely unknown. So, purpose study to evaluate TEAS gastrectomy. Patients Methods: We recruited 96 with gastric cancer from May 2019 November 2019; 82 were enrolled, 81 completed. randomly assigned group (TG) received on day (POD) 1– 3 or control...
Autism spectrum disorder (ASD) is a complex neurodevelopmental condition with poorly understood etiology. Recent studies have suggested that metabolic dysregulation might be linked to the development of ASD; however, causal relationships remain unclear. This study aimed investigate association between these factors using two-sample Mendelian randomization (TSMR). We conducted TSMR analysis assess relationship blood metabolites and ASD summarized GWAS data. The metabolite dataset from...
Background With the increasing number of cancer treatments, emergence multidisciplinary teams (MDTs) provides patients with personalized treatment options. In recent years, artificial intelligence (AI) has developed rapidly in medical field. There been a gradual tendency to replace traditional diagnosis and AI. IBM Watson for Oncology (WFO) proven be useful decision-making breast lung cancer, but date, research on gastric is limited. Objective This study compared concordance WFO MDT...
Abstract Background Studies on robotic total gastrectomy (RTG) are currently limited. This study aimed to compare the intraoperative performance as well short‐ and long‐term outcomes of RTG laparoscopic (LTG). Methods A 969 patients underwent ( n = 161) or 636) between October 2014 2021. The two groups were matched 1:3 using propensity score matching (PSM) method. 147) 371) compared. Results After matching, estimated blood loss was lower (80.51 ± 68.77 vs. 89.89 66.12, p 0.008), number lymph...
Introduction Gastric cancer (GC) diagnosed in the elderly population has become a serious public health problem worldwide. Given combined effects of frailty and consequences treatment, older individuals with GC are more likely than young patients to suffer from postoperative complications poor clinical outcomes. Nutrition, functional capacity psychological state-based multimodal prehabilitation, which is dominated by Enhanced Recovery After Surgery (ERAS) pathway management, been shown...
The aim of this multicentre cohort study was to compare the long-term oncological outcomes robotic gastrectomy (RG) and laparoscopic (LG) for patients with gastric cancer.
BACKGROUND At present, the enhanced recovery after surgery (ERAS) protocol is widely implemented in field of gastric surgery. However, effect ERAS on long-term prognosis cancer has not been reported. AIM To compare effects and conventional protocols short-term outcomes laparoscopic gastrectomy. METHODS We retrospectively analyzed data 1026 consecutive patients who underwent gastrectomy between 2012 2015. The were divided into either an group or a group. groups matched 1:1 ratio using...
Neuro-oncological ventral antigen 1 (NOVA1) is a neuron-specific RNA-binding protein which regulates alternative splicing in the developing nervous system. Recent research has found that NOVA1 plays significant role carcinogenesis. In this paper, we examine of non-small cell lung cancer (NSCLC) and its underlying molecular mechanisms.The expression NSCLC was detected by immunohistochemistry correlations between clinicopathological factors were analyzed chi-square tests. Kaplan-Meier survival...
Objective: This study aimed to compare the effects of ERAS and conventional programs on short-term outcomes after LDG. Summary Background Data: Currently, program is broadly applied in surgical areas. Although several benefits LDG with have been covered, high-level evidence still limited, specifically advanced gastric cancer. Methods: The present was designed as a randomized, multicenter, unblinded trial. enrollment criteria included histologically confirmed cT2-4aN0-3M0 adenocarcinoma....
To evaluate the multiple factors influencing survival of elderly patients with locally advanced gastric cancer (LAGC) and develop validate novel nomograms for predicting survival.The clinical features treated between 2000 2018 were collected collated from Surveillance, Epidemiology, End Results (SEER) database three medical centres in China, randomly divided into a training cohort (3494), internal validation (1497) external (841). Univariate multivariate analyses prognostic values performed...
The 1092 bp F3H gene from Trapa bispinosa Roxb., which was named TbF3H, cloned and it encodes 363 amino acids. Bioinformatic phylogenetic tree analyses revealed the high homology of TbF3H with flavanone 3-hydroxylase other plants. A functional analysis showed that Roxb. encoded a 3-hydroxylase; catalyzed formation dihydrokaempferol (DHK) naringenin in S. cerevisiae. promoter strengths were compared by fluorescence microscopy flow cytometry detection intensity reporter genes initiated each...
Hepatocellular carcinoma (HCC) is a common gastrointestinal malignancy characterized by high incidence rates and poor prognosis. Common treatment modalities include surgery, ablation, transarterial chemoembolization (TACE). Hepatic arterial infusion chemotherapy (HAIC) has long been used in the of unresectable liver cancer. In recent years, combination anti-angiogenesis therapy immune checkpoint inhibitors shown significant advances middle- advanced-stage This report presents case HCC which...
Mitogen-inducible gene 6 (Mig-6) is a tumor suppressor that plays an important role in many types of cancers by interacting with EGFR.However, its molecular mechanism hepatocellular carcinoma (HCC) and relationship miRNAs need to be elucidated.Therefore, this study aimed explore whether Mig-6 could promote apoptosis the inhibition autophagy via downstream miRNA HCC cell lines.We used two lines, HepG2 HLE, establish overexpression knockdown experiments, as well miR-193a mimic inhibitor...