A5101914336- Liver Disease and Transplantation
- Liver Disease Diagnosis and Treatment
- Organ Transplantation Techniques and Outcomes
- MicroRNA in disease regulation
- Microscopic Colitis
- Circular RNAs in diseases
- Helicobacter pylori-related gastroenterology studies
- Gastric Cancer Management and Outcomes
- Inflammatory Bowel Disease
- Colorectal Cancer Screening and Detection
- Cancer-related molecular mechanisms research
- Hepatitis Viruses Studies and Epidemiology
- RNA Interference and Gene Delivery
- Gastroesophageal reflux and treatments
- Cardiac Arrhythmias and Treatments
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Enhanced Recovery After Surgery
- Eosinophilic Disorders and Syndromes
- RNA Research and Splicing
- RNA modifications and cancer
- Esophageal and GI Pathology
- Atrial Fibrillation Management and Outcomes
- Glycosylation and Glycoproteins Research
- Colorectal Cancer Surgical Treatments
- Cardiac pacing and defibrillation studies
National Clinical Research Center for Digestive Diseases
2017-2025
Xijing Hospital
2016-2025
First Hospital of Shanxi Medical University
2025
Shanxi Medical University
2025
Air Force Medical University
2015-2024
Tumor Hospital of Xinjiang Medical University
2024
Xinjiang Medical University
2024
Nanjing Drum Tower Hospital
2023
Fujian Provincial Hospital
2023
Fujian Medical University
2023
Aliment Pharmacol Ther 2011; 33: 50–63 Summary Background Infection following abdominal operation remains a major factor affecting the morbidity of patients after surgery. Aim To determine effects perioperative administration probiotics on gut barrier function and surgical outcome in undergoing elective colorectal Methods One hundred with carcinoma were randomly divided into control group ( n = 50) 50). The given orally for 6 days preoperatively 10 post‐operatively. Outcomes measured by...
Multidrug resistance remains a major obstacle to successful treatment for patients with gastric cancer (GC). Recently, glycosylation has been demonstrated play vital role in the acquisition of multidrug resistance. As potent inhibitor glycosylation, tunicamycin (Tu) shown marked antitumor activities various cancers. In present study, we attempted determine exact effect Tu on chemoresistance GC. The cytotoxic effects drugs GC cells were evaluated by cell viability assays, and apoptosis was...
Abstract Background and objective Gastric cancer (GC) remains a significant global health challenge, characterized by high incidence mortality rates, particularly in East Asia. A comprehensive understanding of the disease burden gastric is crucial for developing effective prevention treatment strategies. However, assessments remain limited. This study, based on Global Burden Disease (GBD) framework, systematically analyzes trends from 1990 to 2021 projects future through 2035, aiming provide...
Objective Limited data are available on the prevention of variceal rebleeding in cirrhotic patients with portal vein thrombosis (PVT). This study aimed to compare transjugular intrahepatic portosystemic shunt (TIPS) covered stents versus endoscopic band ligation (EBL) plus propranolol for among cirrhosis and PVT. Design Consecutive (94% Child-Pugh class A or B) PVT who had bleeding past 6 weeks were randomly assigned TIPS group (n=24) EBL (EBL+drug, n=25), respectively. Primary endpoint was...
// Qiong Wu 1,* , Zhiping Yang Lin Xia Yongzhan Nie 1 Kaichun Yongquan Shi and Daiming Fan State Key Laboratory of Cancer Biology Xijing Hospital Digestive Diseases, Hospital, Fourth Military Medical University, Xi’an, China * These authors contributed equally to this work Correspondence: Fan, email: Shi, Keywords : MiR-129-5p, Gastric cancer, Drug resistance, ABC transporters Received April 28, 2014 Accepted October 18, Published Abstract Recent studies have reported that...
Human gastric cancers contain a population of cancer stem cells (GCSCs) that can undergo self-renewal and multipotent differentiation. GCSCs be enriched with EpCAM+/CD44+ cells. However, the underlying mechanisms controlling balance GCSC differentiation remain to explored. Because miRNAs regulate cell fates, we compared miRNA expression in tumorspheric more differentiated We found miR-17-92 cluster members miR-19b, miR-20a miR-92a were gradually reduced during GCSCs. Therefore, speculated...
The expression of miR-203 has been reported to be significantly down-regulated in esophageal cancer. We showed here that overexpression cancer cells dramatically increased cell apoptosis and inhibited proliferation, migration invasion as well tumor growth miR-21 expression. subsequently identified small GTPase Ran was a target gene miR-203. Furthermore, restoration partially counteracted the suppressive effects Taken together, our findings suggest may act novel suppressor through...