A5057008099- Coronary Interventions and Diagnostics
- Cardiac Imaging and Diagnostics
- Acute Myocardial Infarction Research
- Cardiac Valve Diseases and Treatments
- Antiplatelet Therapy and Cardiovascular Diseases
- Cerebrovascular and Carotid Artery Diseases
- Peripheral Artery Disease Management
- Aortic aneurysm repair treatments
- Mechanical Circulatory Support Devices
- Obstructive Sleep Apnea Research
- Cardiac Structural Anomalies and Repair
- Cardiovascular Function and Risk Factors
- Vascular Procedures and Complications
- Lipoproteins and Cardiovascular Health
- Integrated Circuits and Semiconductor Failure Analysis
- Atrial Fibrillation Management and Outcomes
- Cancer-related molecular mechanisms research
- Health Systems, Economic Evaluations, Quality of Life
- Apelin-related biomedical research
- Kruppel-like factors research
- Cardiovascular and Diving-Related Complications
- Berberine and alkaloids research
- Inflammatory Biomarkers in Disease Prognosis
- Lipid metabolism and disorders
- Cardiac and Coronary Surgery Techniques
Nanjing Medical University
2015-2024
Jiangsu University
2019
Yixing People's Hospital
2019
Soochow University
2014
Fu Wai Hospital
2014
Shanghai Jiao Tong University
2009
Mount Sinai Beth Israel
2008-2009
Beijing Anzhen Hospital
2008-2009
Capital Medical University
2008-2009
Shanghai Chest Hospital
2008-2009
The aim of this study was to explore the difference in target vessel failure (TVF) 3 years after intravascular ultrasound (IVUS) guidance versus angiographic among all comers undergoing second-generation drug-eluting stent (DES) implantation.The multicenter randomized ULTIMATE (Intravascular Ultrasound Guided Drug Eluting Stents Implantation "All-Comers" Coronary Lesions) trial showed a lower incidence 1-year TVF IVUS-guided DES implantation compared with guidance. However, 3-year clinical...
Abstract Aim The present study aimed to assess the benefits of two-stent techniques for patients with DEFINITION criteria-defined complex coronary bifurcation lesions. Methods and results In total, 653 lesions at 49 international centres were randomly assigned undergo systematic technique (two-stent group) or provisional stenting (provisional group). primary endpoint was composite target lesion failure (TLF) 1-year follow-up, including cardiac death, vessel myocardial infarction (TVMI),...
This study sought to compare angiographic endpoints at one-year follow-up after a drug-eluting stent implantation guided by either intravascular ultrasound (IVUS) or angiography in patients with chronic total occlusion (CTO) lesions.Patients least one CTO lesion recanalised successfully were randomly assigned the IVUS-guided angiography-guided group. The use of IVUS for penetration true lumen and optimisation expansion was only done primary endpoint in-stent late loss (LLL) follow-up. A 230...
Background: Ginsenoside Rg1, an important and active ingredient of Panax ginseng, has been shown to exert cardioprotective effects in vivo. The present study aimed test the hypothesis that ginsenoside Rg1 attenuates cardiac dysfunction a transverse aortic constriction (TAC)–induced left ventricular hypertrophy vivo via proangiogenic antifibrotic effects. Methods: This investigated rat model TAC-induced hypertrophy. Cardiac function was assessed by echocardiography. were histopathology mRNA...
The present study aimed to test the hypothesis that berberine, a plant-derived anti-oxidant, attenuates adverse left ventricular remodelling and improves cardiac function in rat model of myocardial infarction (MI). Furthermore, potential mechanisms mediated cardioprotective actions particular effect on autophagy, were also investigated. Acute MI was induced by ligating anterior descending coronary artery Sprague-Dawley rats. Cardiac assessed transthoracic echocardiography. protein...
Background The effects of intravascular ultrasound (IVUS)‐guided complex approaches using drug‐eluting stents (DES) for coronary bifurcation lesions on clinical outcomes has not yet been studied in detail. Objective Our objective was to analyze the difference 1‐year following two‐stent techniques involving implantation DES between IVUS‐guided and angiography‐guided groups. Methods From May 26, 2007 March 24, 2010, 628 patients received (324 group 304 angiography‐guided) were prospectively...
Background: The importance of intravascular ultrasound (IVUS)-guided stenting the unprotected left main coronary artery (ULMCA) remains controversial and has not been fully studied in subset patients with ULMCA. This study evaluated clinical outcome IVUS-guided using a drug-eluting stent for Methods: A total 1,016 consecutive ULMCA stenosis who underwent implantation from January 2006 to December 2011 were prospectively registered. primary endpoint this nonrandomized registry was rate...
MicroRNA-210 (miRNA-210) has been reported to be associated with angiogenesis and may serve important roles in acute myocardial infarction (AMI), which remain unclear. The present study sought evaluate the efficacy of miRNA‑210 AMI examine potential mechanisms. models were established Sprague‑Dawley rats. expression was upregulated via transfection lentivirus‑mediated agonists quantitative analysis performed using reverse transcription‑quantitative polymerase chain reaction (RT‑qPCR)....
The present study aimed to compare the long-term (five-year) safety and efficacy between one-stent, two-stent double-kissing (DK) crush strategies, utilising drug-eluting stents, for unprotected left main coronary artery (ULMCA) bifurcation lesions.Between March 2004 April 2007, 633 consecutive patients with ULMCA lesions (232 in one-stent group 401 group) were prospectively enrolled. primary endpoint was occurrence of major adverse cardiac events (MACE), a composite death, myocardial...
The mechanism of miR-30a in myocardial fibrosis rats with infarction (MI) was investigated. rAAV9-miR-30a constructed and transfected to heart via injecting into the left ventricular cavity MI rats. sham operation group, control group miR‑30a-NC were established. Besides, 3'-UTR CTGF inserted luciferase expression plasmid (pMir‑report), then COS1 cells. miRNA were, respectively, cotransfected detected before after knockdown binding site CTGF. Four weeks surgery, cardiac function measured by...