A5101790299- Gastric Cancer Management and Outcomes
- Metastasis and carcinoma case studies
- Gastrointestinal Tumor Research and Treatment
- Ferroptosis and cancer prognosis
- Colorectal Cancer Surgical Treatments
- Genetic factors in colorectal cancer
- Animal Disease Management and Epidemiology
- Viral Infections and Immunology Research
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Cancer Immunotherapy and Biomarkers
- Colorectal Cancer Treatments and Studies
- Animal Virus Infections Studies
- Ginseng Biological Effects and Applications
- Viral gastroenteritis research and epidemiology
- Vascular Malformations and Hemangiomas
- Pancreatic and Hepatic Oncology Research
- Barrier Structure and Function Studies
- Chromium effects and bioremediation
- Hepatitis B Virus Studies
- Pelvic and Acetabular Injuries
- Gastrointestinal disorders and treatments
- Chromatography in Natural Products
- Esophageal and GI Pathology
- Colorectal and Anal Carcinomas
- Virus-based gene therapy research
First Affiliated Hospital of Nanchang University
2011-2024
First Affiliated Hospital of Jiangxi Medical College
2024
Nanchang University
2011-2024
Yanbian University
2011-2018
Abstract Background Colon cancer is a disease with high malignancy and incidence in the world. Tumor immune microenvironment (TIM) tumor mutational burden (TMB) have been proved to play crucial roles predicting clinical outcomes therapeutic efficacy, but correlation between them underlying mechanism were not completely understood colon cancer. Methods In this study, we used Single-Sample Gene Set Enrichment Analysis (ssGSEA) unsupervised consensus clustering analysis divide patients from...
Objective: A large-scale multicenter retrospective cohort study was conducted to compare the short- and long-term outcomes of robotic gastrectomy (RG) laparoscopic (LG) for gastric cancer. Summary Background Data: RG is being increasingly used worldwide, but data from studies on oncologic versus LG are limited. The potential benefits compared with cancer remain controversial. Methods: Data eligible patients who underwent or 11 experienced surgeons 7 centers in China between March 2010...
Objective: To compare the short- and long-term outcomes between robotic gastrectomy (RG) laparoscopic (LG) for gastric cancer. Summary Background Data: The clinical of RG over LG have not yet been effectively demonstrated. Methods: This retrospective cohort study included 3,599 patients with cancer who underwent radical at eight high-volume hospitals in China from August 2016 to June 2019. Propensity score matching (PSM) was performed received LG. primary endpoint 3-year disease-free...
Reports in the field of robotic surgery for gastric cancer are increasing. However, studies only on patients with advanced (AGC) lacking. This retrospective study was to compare short-term outcomes robotic-assisted distal gastrectomy (RADG) and laparoscopic-assisted (LADG) D2 lymphadenectomy AGC. From December 2014 November 2019, 683 consecutive AGC underwent mini-invasive assisted gastrectomy. Propensity-score matching (PSM) analysis conducted reduce patient selection bias. Short-term were...
Robotic-assisted surgery, a developed technology, is becoming more and accepted by surgeons. However, the comparison between robotic-assisted total gastrectomy (RATG) conventional laparoscopy-assisted (LATG) for advanced gastric cancer (AGC) seldom reported, or usually sample sizes reported are small. The current research was designed to compare short-term outcomes of RATG LATG with D2 lymphadenectomy AGC in mono-institution from China. A 205 patients June 2015 October 2018 were included...
Studies on surgical outcomes after robotic surgery are increasing; however, long-term oncological results of studies comparing robotic-assisted distal gastrectomy (RADG) versus laparoscopic-assisted (LADG) for advanced gastric cancer (AGC) still limited. This study aimed to assess the and RADG LADG treatment AGC.A total 1164 consecutive AGC patients undergoing or were enrolled between January 2015 October 2021. Propensity score-matched (PSM) analysis was performed minimize selection bias....
Colorectal cancer (CRC) is one of most malignant tumors, mainly due to its high rate metastasis and recurrence. The prognosis CRC difficult early patients have no specific symptoms. Therefore, it emergent identify a biomarker for prognosis. Cystatin SN (CST1) shows elevated expression in many but role CRCs still unknown. Through immunohistochemistry analysis, we found that CST1 was upregulated samples. survival analysis had demonstrated closely associated with poor clinical status, providing...
Abstract Background Robotic surgery has been taken as a new modality to surpass the technical limitations of conventional surgery. Here we aim compare oncologic outcomes patients with rectal cancer receiving robotic vs. laparoscopic Methods Data from diagnosed between March 2011 and December 2018 were obtained for outcome assessment at First Affiliated Hospital Nanchang University. All separated into two groups: robot group (patients surgery, n = 314) laparoscopy 220). The primary endpoint...
Background/Aim. Exosomal miRNAs are promising tumor biomarkers. This research explored the diagnostic value of serum exosomal by analyzing derived from gastric cancer patients. Methods. Deep sequencing was performed using an Illumina HiSeq2500 sequencer on samples three healthy subjects in normal control group (group N) and six patients treatment T). Bioinformatics analysis miRNA profiles to screen differentially expressed miRNA. In addition, target gene prediction, GO, KEGG pathway...
Colon cancer is one of the most common tumors in digestive tract. Studies left-side colon (LCC) and right-side (RCC) show that these two subtypes have different prognoses, outcomes, clinical responses to chemotherapy. Therefore, a better understanding importance classifications anatomic needed.We collected patients' transcriptome data, information, somatic mutation data from Cancer Genome Atlas (TCGA) database portal. The were taken 390 patients (172 LCC samples 218 RCC samples); included...
Duodenal cavernous haemangiomas are rare, benign disorders, and massive gastrointestinal (GI) bleeding is a rare clinical condition. The present case report describes 50-year-old male patient who presented with severe, ongoing haematochezia. A peripheral blood smear at the time of admission showed significant anaemia, haemoglobin level was 52 g/l (normal range, 120–175 g/l). Albumin also low 28 40–55 Standard computed tomography (CT) mural thickening relative lumen stenosis in ascending...
With the improvement of anastomotic techniques and iteration instruments, robotic intracorporeal suturing has become increasingly proficient. The era fully anastomosis in gastric cancer resection is emerging. This study aims to explore impact totally distal gastrectomy (TRDG) robotic-assisted (RADG) on patients' quality life.
Colon cancer is the third most common malignant tumor in world. Although immunotherapy has been used treatment, there still no first-line method for colon cancer. Therefore, it essential to search potential targets and molecular biomarkers early diagnosis prognosis.In this study, we downloaded transcriptome data from The Cancer Genome Atlas (TCGA) immune-related genes ImmPort database. Then filtered with prognostic value constructed an signature. Patients were classified into low- high-risk...
Animal infectious diseases pose a serious and continuing threat to the animal health cause huge economic losses throughout world. Vaccination is one of most effective solutions prevent control diseases. With development biotechnologies need for disease prevention control, focus vaccine research has been shifted safe, efficient, broad-spectrum, low-dose marker vaccines. Novel vaccines capable inducing high levels both humoral cellular immune responses are promising provide more efficient...
Objectives MSD is a type of bio sugar made by an MS research institute in South Korea. The has glycan structure with functional group on the monosaccharide. Our objective was to observe effects different concentrations toad sciatic nerve-trunk action potential, and whether can improve inhibitory effect potential hypertonic glucose solution. Methods Toad nerve trunks were randomly divided into three groups, namely control group, group. Following soaking MSD, amplitudes conduction velocities...