- Neural dynamics and brain function
- Heart Rate Variability and Autonomic Control
- Tryptophan and brain disorders
- Functional Brain Connectivity Studies
- Nonlinear Dynamics and Pattern Formation
- Stress Responses and Cortisol
- Optical Imaging and Spectroscopy Techniques
- EEG and Brain-Computer Interfaces
- Adipokines, Inflammation, and Metabolic Diseases
- Smart Parking Systems Research
- Adenosine and Purinergic Signaling
- Collaboration in agile enterprises
- Image and Signal Denoising Methods
- Vehicle Routing Optimization Methods
- Plant-based Medicinal Research
- Obstructive Sleep Apnea Research
- Heat Transfer and Boiling Studies
- Neuroinflammation and Neurodegeneration Mechanisms
- Hearing, Cochlea, Tinnitus, Genetics
- Vestibular and auditory disorders
- Recycled Aggregate Concrete Performance
- Fluid Dynamics and Thin Films
- stochastic dynamics and bifurcation
- Transportation and Mobility Innovations
- Protein Structure and Dynamics
Fudan University
2017-2022
Jiangsu University
2021
State Key Laboratory of Medical Neurobiology
2017-2019
Shanghai Medical College of Fudan University
2018-2019
China University of Petroleum, East China
2018
Anhui Provincial Hospital
2009
Depression is a heterogeneous disorder, with the exact neuronal mechanisms causing disease yet to be discovered. Recent work suggests it accompanied by neuro-inflammation, characterized, in particular, microglial activation. However, activation and its involvement neuro-inflammation stress-related depressive disorders are far from understood.We utilized multiple detection methods detect hippocampus of rats after exposure chronic mild stress (CMS). Male Sprague Dawley (SD) were subjected...
In recent years, proinflammatory cytokine interleukin-1β (IL-1β) was considered to play a critical role in the pathogenesis of depression. addition, P2X7 receptor (P2X7R), member purinergic family, which is predominantly present on microglia, as well astrocytes and neurons lesser amounts central nervous system, suggested be involved processing releasing IL-1β. Here, we investigated P2X7R depression.Male Sprague-Dawley rats were subjected chronic unpredictable stressors (CUS) for 3 weeks. At...
Recently, effective connectivity (EC) calculation methods for functional near-infrared spectroscopy (fNIRS) data mainly face two problems: the first problem is that noise can seriously affect EC and even lead to false connectivity; second it ignores various real neurotransmission delays between brain region, instead uses a fixed delay coefficient calculation.To overcome these issues, symbolic phase transfer entropy (dSPTE) proposed by developing traditional (TE) estimate fNIRS. Firstly, time...
This paper presents an experimental study to investigate the heat transfer limit of a micro-grooved OHP at vertical bottom mode. The internal hydraulic diameter is about 2.0 mm, and deionized water was used as working fluid volumetric filling ratios (FRs) ranging from 30% 60%. Experimental results demonstrated that could significantly enhance allowable maximum input flux before occurrence dry-out owing capillary action provided by structures facilitate condensate backflow evaporator....
Heart rate (HR) is an important vital sign for evaluating the physiological condition of a newborn infant. Recently, measuring HR, novel RGB camera-based non-contact techniques have demonstrated their specific superiority compared with other techniques, such as dopplers and thermal cameras. However, they still suffered poor robustness in infants' HR measurements due to frequent body movement.This paper introduces framework improve by solving motion artifact problems. Our solution based on...
Big recycled aggregate self compacting concrete is a new type of concrete, which has the advantages low hydration heat and green environmental protection, but its bending behavior can be affected by different replacement rate. Therefor, in this paper, research status big Recycled was systematically introduced, effect rate on failure mode, crack distribution strength beam were studied through test 4 beams. The results show that: rate; modes beams are same as those ordinary concrete; plane...
Cross-frequency coupling of neural oscillation is widespread during the complex cognitive process. Therefore, identifying cross-frequency information flow essential for revealing dynamics mechanisms in brain network. A current method based on theory, phase transfer entropy (PTE), has been proved its effectiveness estimating directional several recent studies. However, there remains some limits PTE: (1)lack multivariable effect, (2) poor robustness, (3)curse dimensionality high dimensional...
Objective To determine pharmacokinetics profiles of methylprednisolone (MTH) in perilymph and plasma guinea pig after intratympanic injection MTH different concentrations. Methods By auripuncture, three concentrations were used pigs: 32. 0 mg/ml, 40. 0mg/ml 62.5 mg/ml. Samples the scala tympani collected at 1 - 12h administration assayed using high-performance liquid chromatography. Auditory brainstem response (ABR) was detected before administration. Results The dose-related. differences...
In quantifying the complexity characteristics of neurophysiological signals, most advanced entropy methods still have some inevitable limitations, such as poor accuracy, robustness, and reliability. This study proposed a novel estimator, termed "cumulative residual symbolic dispersion (CRSDE)," to address these limits improve analysis performance. Meanwhile, corresponding time-shift multiscale version, TCRSDE, is also introduced describe irregularity time series on multiple scales. The CRSDE...