Alfredo Carlos Simões Dornellas de Barros

ORCID: 0000-0003-2535-3040
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About
Contact & Profiles
Research Areas
  • Women's cancer prevention and management
  • Breast Cancer Treatment Studies
  • Breast Lesions and Carcinomas
  • Breast Implant and Reconstruction
  • Maternal and Neonatal Healthcare
  • Cancer Risks and Factors
  • Pregnancy and preeclampsia studies
  • Cancer and Skin Lesions
  • Cancer Diagnosis and Treatment
  • BRCA gene mutations in cancer
  • Reconstructive Surgery and Microvascular Techniques
  • Global Maternal and Child Health
  • Hemoglobinopathies and Related Disorders
  • Global Cancer Incidence and Screening
  • Advanced Radiotherapy Techniques
  • Male Breast Health Studies
  • Reconstructive Facial Surgery Techniques
  • Maternal and fetal healthcare
  • Lymphoma Diagnosis and Treatment
  • Circular RNAs in diseases
  • MicroRNA in disease regulation
  • Salivary Gland Tumors Diagnosis and Treatment
  • Cancer Genomics and Diagnostics
  • Anesthesia and Pain Management
  • Metastasis and carcinoma case studies

Hospital Sírio-Libanês
2011-2024

Universidade de São Paulo
2002-2023

Beneficência Portuguesa de São Paulo
2020-2023

Hospital São Paulo
2022

Cosmote (Greece)
2016

Irmandade da Santa Casa de Misericórdia de São Paulo
2013

Plastic Surgery Hospital
2013

Hospital das Clínicas da Universidade Federal de Minas Gerais
2013

Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
2005

Abstract Surgery is the first-line treatment for early, localized, or operable breast cancer. Regional anesthesia during mastectomy may offer prevention of postoperative pain. One potential protocol combination serratus anterior plane block (SAM block) with pectoral nerve I (PECS I), but results and benefits are limited. Our study compared general without SAM + PECS radical axillary node dissection reconstruction using evaluations pain, opioid consumption, side effects serum levels...

10.1038/s41598-018-26273-z article EN cc-by Scientific Reports 2018-05-14

The purpose of the study was to evaluate results application a nonpharmacologic treatment based on explanations and reassurance women with mastalgia. A total 121 were studied. They received underwent follow up questionnaire 2-3 months later. An original methodology efficiency mastalgia employed, which consisted comparing pain parameters patients before after treatment. authors verified success rate 70.2% (n = 85) reassurance. When evaluating intensity symptom, effective in 85.7% mild form...

10.1046/j.1524-4741.1999.98089.x article EN The Breast Journal 1999-05-01

Este estudo tem como objetivo promover o conhecimento do impacto psicológico produzido pelo câncer de mama através da revisão literatura internacional. A médica, costuma avaliar as alterações psicológicas por que passam mulheres com mama, meio questionários e/ou inventários qualidade vida, aplicados em pacientes no pós-operatório. Estas pesquisas são ambíguas suas conclusões, ora mencionando quanto mais conservadora a cirurgia menor causado pelas na imagem corporal dizendo não há diferenças...

10.32635/2176-9745.rbc.2005v51n2.1974 article PT cc-by Revista Brasileira de Cancerologia 2005-06-30

Abstract Breast cancer is the second most common diagnosed type of in women. Chronic neuropathic pain after mastectomy occurs frequently and a serious health problem. In our previous single-center, prospective, randomized controlled clinical study, we demonstrated that combination serratus anterior plane block (SAM) pectoral nerve I (PECS I) with general anesthesia reduced acute postoperative pain. The present report describes prospective follow-up study this published to investigate...

10.1038/s41598-023-31589-6 article EN cc-by Scientific Reports 2023-03-21

While the optimal management of early breast cancer patients with sentinel lymph node (SLN) involvement mapped in internal thoracic chain is still debated, biopsy may be performed when surgeons select who are most likely to benefit. The aim this study examine anatomical aspects nodes (ITNs) orientate SLN parasternal area.

10.1186/s12957-016-0897-2 article EN cc-by World Journal of Surgical Oncology 2016-04-30

Purpose: Sentinel node (SN) biopsy is a reliable method for improved staging of breast cancer, offering an alternative to routine axillary dissection. Perhaps preoperative chemotherapy could increase the rate false-negative SN because induced lymphatic changes. The aim study was evaluate utility lymphoscintigraphy and hand-held probe detection in approach after chemotherapy, correlating it with histologic analysis axilla. Methods: Eighty-three patients (mean age, 53 years; TNM stage I) were...

10.1097/00003072-200307000-00004 article EN Clinical Nuclear Medicine 2003-06-25

Abstract The risk of developing metastatic disease in breast cancer patients is traditionally predictable based on the number positive axillary lymph nodes, complemented with additional clinicopathological factors. However, since node-negative have a 20–30% probability disease, node information alone insufficient to accurately assess individual risk. Molecular approaches, such as multigene expression panels, analyze set cancer-related genes that more predict early metastasis and treatment...

10.1038/s41523-019-0106-x article EN cc-by npj Breast Cancer 2019-04-05

Imaging of Primary Actinomycosis the BreastNestor de Barros1, Flavia K. Issa1, Alfredo C.S.D. Barros2, Mário S. D'Ávila1, Antonio C. Nisida2, Maria Chammas1, José A. Pinotti2 and Giovanni G. Cerri1Audio Available | Share

10.2214/ajr.174.6.1741784 article EN American Journal of Roentgenology 2000-06-01

A BI-RADS category of 4 from a mammogram indicates suspicious breast lesions, which require core biopsies for diagnosis and have an approximately one third chance being malignant. Human plasma contains many circulating microRNAs, variations in their levels been associated with pathologies, including cancer. Here, we present novel methodology to identify malignant lesions women mammography. First, used the miRNome array qRT-PCR define microRNAs that were differentially represented blood...

10.18632/oncotarget.20806 article EN Oncotarget 2017-09-11

It is now well established that strenuous engagement in aerobic endurance sports may cause menstrual problems and hypoestrogenemia-related phenomena, such as osteoporosis. The present study was designed to assess whether the competitive practice of female judoists produces specific physiological changes menstruation bone muscle metabolism. A test group 17 white (mean VO2max, 50.9 +/- 2.8 mL/kg.min; mean percent body fat, 16.3 3.3%), a reference oarswomen, sedentary women participated this...

10.1210/jcem.80.12.8530613 article EN The Journal of Clinical Endocrinology & Metabolism 1995-12-01

Local recurrences in patients submitted to conservative breast treatment for early infiltrating carcinomas occur 5-10% of the cases and are caused mainly by inadequate local resection remaining residual malignant tissue. The present study was carried out analyze effect intraoperative evaluation surgical margins its influence on immediate management with (T1-T2) scheduled undergo quadrantectomy.A total 102 were studied. After a classical quadrantectomy, done means macroscopic, cytological...

10.1177/030089160308900109 article EN Tumori Journal 2003-01-01

A Revista Brasileira de Cirurgia Plástica é o órgão oficial divulgação da Sociedade (SBCP), tem como objetivo registrar a produção científica em Plástica, fomentar estudo, aperfeiçoamento e atualização dos profissionais especialidade.

10.5935/2177-1235.2017rbcp0073 article PT cc-by Revista Brasileira de Cirurgia Plástica 2017-01-01

Purpose. To assess feasibility, efficacy, toxicity, and cosmetic results of intraoperative radiotherapy (IORT) with electrons delivered by standard linear accelerators (Linacs) during breast conserving surgeries for early infiltrating cancer (BC) treatment. Materials Methods. A total 152 patients invasive ductal carcinoma (T ≤ 3.0 cm) at low risk local relapses were treated. All had unicentric lesions imaging methods negative sentinel node. After a wide excision, 21 Gy on the parenchyma...

10.1155/2014/568136 article EN cc-by International Journal of Breast Cancer 2014-01-01

10.7170/jsis.2011.01.0003 article EN Journal of the Senologic International Society 2011-10-06

Objective: This study evaluated the frequency of GATA-binding protein 3 (GATA3) expression in early breast cancer and its relationship with histopathological immunohistochemical parameters.Materials Methods: GATA3 was analysed by immunohistochemistry histological sections tumors from 105 female patients, diagnosis invasive carcinoma (BC), at clinical stages I, II IIIA, who underwent primary surgical treatment.GATA3 nuclear determined as percentage positive tumor cells further categorized...

10.4274/ejbh.galenos.2022.2022-3-9 article EN cc-by-nc-nd Meme sağlığı dergisi/Meme sağlığı dergisi 2022-07-01
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