A5053420045- Chronic Disease Management Strategies
- Diabetes Treatment and Management
- Parathyroid Disorders and Treatments
- Neural and Behavioral Psychology Studies
- Vitamin D Research Studies
- Pharmacological Effects and Toxicity Studies
- Diabetes Management and Research
- Functional Brain Connectivity Studies
- Neural dynamics and brain function
University of Aberdeen
2023-2025
Aberdeen Royal Infirmary
2023
International guidelines give greatly varying definitions of 25-hydroxyvitamin D (25OHD) insufficiency and deficiency. Vitamin testing is increasing despite 2016 UK guidance for adults advising routine vitamin supplementation October-March year-round high risk groups. A service evaluation biochemical osteomalacia in the North-East Scotland (57-58°N) could inform guidance. We identified adult 25OHD requests 8/7/2008-29/2/2020 albumin-adjusted serum calcium (aCa), parathyroid hormone (PTH)...
Internationally, chronic disease represents a major healthcare challenge for the 21<sup>st</sup> century. Prognostic tools that streamline and target care have been developed cardiovascular disease. This study illustrates how routine data can be used to develop other diseases; using kidney (a precursor of renal replacement therapy (RRT: dialysis or transplantation) requirement) as model. Routine clinical data—serum creatinine measure function), RRT initiation death registration were identify...
Abstract Apathy is a common and disabling complication of Parkinson’s disease characterised by reduced goal-directed behaviour. Several studies have reported dysfunction within pre-frontal cortical regions projections from brainstem nuclei whose neuromodulators include dopamine, serotonin noradrenaline. Work in animal human neuroscience confirmed contributions these on aspects motivated decision making. Specifically, non-dopaminergic neuromodulators, influence decisions to explore...