Muhammad Afzal

ORCID: 0000-0003-2570-3223
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About
Contact & Profiles
Research Areas
  • Natural product bioactivities and synthesis
  • Natural Antidiabetic Agents Studies
  • Cancer-related molecular mechanisms research
  • Phytochemicals and Antioxidant Activities
  • Essential Oils and Antimicrobial Activity
  • Medicinal Plants and Neuroprotection
  • Bioactive Compounds and Antitumor Agents
  • Advanced Drug Delivery Systems
  • Monetary Policy and Economic Impact
  • Nanoparticle-Based Drug Delivery
  • Drug-Induced Hepatotoxicity and Protection
  • Global Financial Crisis and Policies
  • Phytochemistry and Biological Activities
  • Pharmacological Effects of Natural Compounds
  • Tryptophan and brain disorders
  • MicroRNA in disease regulation
  • Circular RNAs in diseases
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Liver Disease Diagnosis and Treatment
  • Computational Drug Discovery Methods
  • Curcumin's Biomedical Applications
  • RNA modifications and cancer
  • Synthesis and Reactions of Organic Compounds
  • Cholinesterase and Neurodegenerative Diseases
  • Alzheimer's disease research and treatments

Batterjee Medical College
2023-2025

Government College University, Faisalabad
2013-2025

University of Lahore
2022-2024

St. George's University
2023-2024

University of Jeddah
2024

University of Sialkot
2024

University of Education
2024

University of Okara
2024

KTH Royal Institute of Technology
2017-2023

Jouf University
2017-2023

Aging-related diseases (ARDs) are a major global health concern, and the development of effective therapies is urgently needed. Kaempferol, flavonoid found in several plants, has emerged as promising candidate for ameliorating ARDs. This comprehensive review examines Kaempferol's chemical properties, safety profile, pharmacokinetics, highlights its potential therapeutic utility against underpinned by distinctive structure, which confers antioxidative anti-inflammatory properties. Kaempferol...

10.1016/j.exger.2024.112389 article EN cc-by Experimental Gerontology 2024-03-08

Lung inflammatory disorders are a major global health burden, impacting millions of people and raising rates morbidity death across many demographic groups. An industrial chemical common environmental contaminant, formaldehyde (FA) presents serious concerns to the respiratory system, including onset aggravation lung disorders. Epidemiological studies have shown significant associations between FA exposure levels incidence severity several diseases. causes inflammation in tract via...

10.1016/j.cbi.2024.111002 article EN cc-by Chemico-Biological Interactions 2024-04-09

Parkinson's disease (PD) is a degenerative neurological condition marked by the gradual loss of dopaminergic neurons in substantia nigra pars compacta. The precise etiology PD remains unclear, but emerging evidence suggests significant role for disrupted autophagy-a crucial cellular process maintaining protein and organelle integrity.

10.1111/cns.14763 article EN cc-by CNS Neuroscience & Therapeutics 2024-05-01

Sterubin, a flavanone is an active chemical compound that possesses neuroprotective activity. The current investigation was intended to assess the sterubin effect in scopolamine-activated Alzheimer's disease. rats were induced with scopolamine (1.5 mg/kg) followed by treatment (10 for 14 days. Behavioural analysis predictable Y-maze test and Morris water test. Biochemical variables like nitric oxide acetylcholinesterase, Choline acetyltransferase, antioxidant markers superoxide dismutase,...

10.1016/j.sjbs.2023.103560 article EN cc-by-nc-nd Saudi Journal of Biological Sciences 2023-01-13

This study was conducted to measure the antibacterial activity of grape (Vitis vinifera L; Vitaceae) seed extract against methicillin-resistant Staphylococcus aureus (MRSA). Grape and skin extracts were tested for forty-three strains MRSA by gel diffusion, growth respirometric studies. All found be sensitive extract. Complete inhibition all bacterial observed at a concentration 3 mg/ml crude proanthocyanidins (GPSE), equivalent 20.7 µg/ml flavonoid content. Antibacterial bactericidal as...

10.2131/jts.35.357 article EN The Journal of Toxicological Sciences 2010-01-01
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