A5082199143- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Microbial Metabolic Engineering and Bioproduction
- Biofuel production and bioconversion
- Fungal and yeast genetics research
- Crystallography and molecular interactions
- Phosphorus and nutrient management
- Zeolite Catalysis and Synthesis
- Plant nutrient uptake and metabolism
- Constructed Wetlands for Wastewater Treatment
- Wastewater Treatment and Nitrogen Removal
- Algal biology and biofuel production
- Biochemical and Molecular Research
- Photosynthetic Processes and Mechanisms
- finance, banking, and market dynamics
- Nonlinear Optical Materials Studies
- Ammonia Synthesis and Nitrogen Reduction
- Aquatic Ecosystems and Phytoplankton Dynamics
- Virus-based gene therapy research
- Boron Compounds in Chemistry
- Intermetallics and Advanced Alloy Properties
- Genomics and Rare Diseases
- Photonic Crystals and Applications
- Amino Acid Enzymes and Metabolism
- Catalytic C–H Functionalization Methods
Ocean University of China
2019-2023
Beijing Normal University
2022-2023
Guangzhou Medical University
2015-2022
Huaiyin Institute of Technology
2019
University of Illinois Urbana-Champaign
2014-2018
Zhejiang University
2013
Shenyang Agricultural University
2011
Northeast Normal University
2011
Microorganisms commonly exhibit preferential glucose consumption and diauxic growth when cultured in mixtures of other sugars. Although various genetic perturbations have alleviated the effects repression on specific sugars, a broadly applicable mechanism remains unknown. Here, we report that reduction rate phosphorylation alleviates Saccharomyces cerevisiae. Through adaptive evolution under mixture xylose analog 2-deoxyglucose, isolated mutant strain capable simultaneously consuming xylose....
ABSTRACT Saccharomyces cerevisiae has limited capabilities for producing fuels and chemicals derived from acetyl‐CoA, such as isoprenoids, due to a rigid flux partition toward ethanol during glucose metabolism. Despite numerous efforts, xylose fermentation by engineered yeast harboring heterologous metabolic pathways was not efficient ethanol. Therefore, we hypothesized that metabolism might be better fit non‐ethanol metabolites. We indeed found S. on showed higher expression levels of the...
ABSTRACT The haloacid dehalogenase (HAD) superfamily is one of the largest enzyme families, consisting mainly phosphatases. Although intracellular phosphate plays important roles in many cellular activities, biological functions HAD enzymes are largely unknown. Pho13 1 16 putative Saccharomyces cerevisiae . has not been studied extensively, but previous studies have identified PHO13 to be a deletion target for generation industrially attractive phenotypes, namely, efficient xylose...
Accumulation of xylitol in xylose fermentation with engineered Saccharomyces cerevisiae presents a major problem that hampers economically feasible production biofuels from cellulosic plant biomass. In particular, substantial due to unbalanced redox cofactor usage by reductase (XR) and dehydrogenase (XDH) leads low yields ethanol. While previous research focused on manipulating intracellular enzymatic reactions improve metabolism, this study demonstrated new strategy reduce formation...
Microalgal cultivation with wastewater can recover nutrients and high value-added products. However, biomass accumulation physiological responses of microalgae under different organic phosphorus (OP) forms have rarely been explored. In this study, the effects three OP forms, including adenosine triphosphate (ATP), glucose-6-phosphate (G-6-P), β-glycerol phosphate (β-GP), on Chlorella pyrenoidosa growth, biochemical composition, morphological characteristic, photosynthesis, cell viability...
Objective To investigate the total protein and surface expression levels of Dravet syndrome associated NaV1.1 truncated mutant F1237fsX1269 in HEK293T cells, explore potential pathogenic mechanism mutation. Methods The wide-type plasmids (pCMV-EYFP-SCN1A-WT) mutation (pCMV-EYFP-3710) expressed EYFP were constructed on templates pCMV-SCN1A-WT; then, these transfected into cells; 48 h after that, input proteins extracted. Western blotting was employed to detect expression; whole cell...