A5101049235- Machine Learning and Data Classification
- Cancer-related molecular mechanisms research
- Psychological Well-being and Life Satisfaction
- Neural Networks and Applications
- Forest Management and Policy
- Graph Theory and Algorithms
- Advanced Graph Neural Networks
- Anomaly Detection Techniques and Applications
- Heart Failure Treatment and Management
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Artificial Intelligence in Healthcare and Education
- RNA modifications and cancer
- Ideological and Political Education
- Domain Adaptation and Few-Shot Learning
- Advanced Computing and Algorithms
- Machine Learning and Algorithms
- Brain Tumor Detection and Classification
- Web Data Mining and Analysis
- Gut microbiota and health
- Cardiac Arrest and Resuscitation
- Nanoplatforms for cancer theranostics
- Health Literacy and Information Accessibility
- Mosquito-borne diseases and control
- Scientific Computing and Data Management
- Advanced Image and Video Retrieval Techniques
Anhui Provincial Meteorological Bureau
2025
Ningbo Center for Disease Control and Prevention
2022-2025
Shandong Provincial Hospital
2025
Shandong University
2025
Changhai Hospital
2022-2025
Inner Mongolia University
2025
Second Military Medical University
2022-2025
Central South University
2025
Institute of Computing Technology
2022-2025
Chinese Academy of Sciences
2022-2025
Abstract Carbon capture, utilization and storage (CCUS) technologies play an essential role in achieving Net Zero Emissions targets. Considering the lack of timely reviews on recent advancements promising CCUS technologies, it is crucial to provide a prompt review advances understand current research gaps pertained its industrial application. To that end, this first summarized developmental history large-scale demonstrations. Then, based visually bibliometric analysis, carbon capture remains...
Knowledge graph (KG) embeddings have shown great power in learning representations of entities and relations for link prediction tasks. Previous work usually embeds KGs into a single geometric space such as Euclidean (zero curved), hyperbolic (negatively curved) or hyperspherical (positively to maintain their specific structures (e.g., chain, hierarchy ring structures). However, the topological structure appears be complicated, since it may contain multiple types simultaneously. Therefore,...
Colorectal cancer (CRC) is a common and deadly disease of the digestive system, but its targeted therapy hampered by lack reliable specific biomarkers. Hence, discovering new therapeutic targets agents for CRC an urgent challenging task. Here we report that carnitine palmitoyltransferase 1A (CPT1A), mitochondrial enzyme catalyzes fatty acid oxidation (FAO), potential target treatment. We show CPT1A overexpressed in cells inhibition secolignan-type compound, 2,6-dihydroxypeperomin B (DHP-B),...
Abnormal lactate metabolism in tumor cells leads to immune escape the microenvironment. Intervening specific metabolic pathways while blocking downstream pyruvate influx holds great promise for overcoming conventional lactate‐targeted therapy limitations such as short half‐life, insufficient consumption, and pathological microenvironment elasticity. Herein, a nanocatalytic medicine based on carbondoping engineered copper nitride enzyme (Cu3N‐C NE) with enhanced oxidase (LOX) activity was...
Neutrophils and albumin had been shown to be independent predictors of mortality from various diseases. Purpose this study was investigate the effect neutrophil-to-albumin ratio (NPAR) as an predictor in heart failure (HF) patients.Data were extracted Medical Information Mart for Intensive Care-III database. Primary outcome 30-day mortality, secondary outcomes in-hospital, 90-day, 365-day length stay (LOS) hospital. Cox proportional hazards regression model receiver operating characteristic...
Potassium (K) has been recognized as an essential element in intensive agricultural production systems, and deficiency of K usually results a decrease crop yields. The utilization potassium-solubilizing bacteria (KSB) to increase the soluble content soil regarded desirable pathway plant Following inoculation KSB soil, potassium can be released (in form K+) consumed by plants. This study aims investigate compare distribution characteristics between forest plantation soils Myanmar. In this...
Abstract Metastasis to the lungs is a leading cause of death for patients with breast cancer. Therefore, effective therapies are urgently needed prevent and treat lung metastasis. In this study, we uncovered mechanism by which NAD(P)H:quinone oxidoreductase 1 (NQO1) orchestrates NQO1 stabilized upregulated peptidyl-prolyl cis-trans isomerase A (PPIA), chaperone that regulates protein conformation activity, preventing its oxidation at critical cysteine residue C161. PPIA subsequently...
Introduction China has the largest population of diabetic patients (about 116 million) in world. As a novel model fat index for Chinese people, visceral adiposity (CVAI) was considered reliable indicator to assess dysfunction fat. This study aimed explore dose–response relationship between CVAI and type 2 diabetes mellitus (T2DM) population, considering as continuous/categorical variable. Method Baseline follow-up data were collected from waves 2011 2015, respectively, Health Retirement...
Systemic inflammation is closely associated with the development and progression of heart failure (HF), increasing vulnerability to thromboembolic events. This retrospective cohort study assessed potential fibrinogen-to-albumin ratio (FAR), a new inflammatory biomarker, as prognostic indicator for HF risk.One thousand one hundred sixty six women 826 men mean age 70.70 ± 13.98 years were extracted from Medical Information Mart Intensive Care-IV (MIMIC-IV v2.0) database. Additionally, second...
Due to climate change and rapid urbanization, the frequency of heatwave events in East China has increased considerably since 21st century, which a considerable influence on human health, such as heatstroke. However, few studies have been conducted this region relationship between heatstroke meteorological conditions. To address point, study aimed analyze characteristics their with conditions Hefei, China. The 2008–2022 data from Hefei Center for Disease Control Prevention was used....
The exosomes are a class of multi-vesicular bodies structures that originated from the cytoplasmic nucleus endosome, which can be synthesized by different cells and released into extracellular environment. Breast cancer-derived promote breast cancer proliferation, metastasis, escape angiogenesis, plays significant role in occurrence development cancer. In this article, we mainly review roles tumor progression immune suppression following aspects. Firstly, introduced, including structure,...
This study examined the associations between health literacy and smoking behaviors among residents in Ningbo City, Zhejiang Province, China, investigating both impact of on prevalence intensity, its potential role cessation interventions. cross-sectional analyzed data from 2,948 male participants 2023 Health Literacy Tobacco Use Surveillance Survey. We applied logistic regression models restricted cubic spline analyses to assess association behaviors, adjusting for demographic...
The current studies of provable robustness for deep neural networks (DNNs) usually assume that the class distribution is overall balanced. However, in real-world applications especially safety-sensitive systems, often exhibits a long-tailed property. It well-known Area Under ROC Curve (AUC) more proper metric learning problems. Motivated by this fact, an AUC-oriented framework (named AUCPro) first proposed paper. key to construct proxy model smoothed isotropic Gaussian noise and then...
Abstract Background Klotho is a type I transmembrane protein known for its anti‐aging, anti‐inflammatory, antioxidative, and cognitive‐enhancing properties. It also exhibits protective effects against systemic lupus erythematosus, sclerosis, other diseases. The aim of this study was to investigate the relationship between serum levels risk rheumatoid arthritis (RA). Methods Participants from National Health Nutrition Examination Survey (NHANES) conducted 2007 2016 were included. Data on RA...
Gastric cancer (GC) is a prevalent malignancy affecting the digestive system. We aimed to develop risk prediction model based on endoscopic atrophy classification for GC. retrospectively collected data from January 2020 October 2021 in our hospital and randomly divided patients into training validation sets an 8:2 ratio. used multiple machine learning algorithms such as logistic regression (LR), Decision tree, Support Vector Machine, Random forest, so establish models. employed Least...
Real-world datasets often exhibit a long-tailed distribution, where vast majority of classes known as tail have only few samples. Traditional methods tend to overfit on these classes. Recently, new approach called Imbalanced SAM (ImbSAM) is proposed leverage the generalization benefits Sharpness-Aware Minimization (SAM) for distributions. The main strategy merely enhance smoothness loss function However, we argue that improving in long-tail scenarios requires careful balance between head and...
Background: Cancer ranks as a leading cause of death worldwide. It is urgent to develop intelligent co-delivery systems for cancer chemotherapy achieve reduced side-effects and enhanced therapeutic efficacy. Methods: We chose oligo-hyaluronic acid (oHA, low molecular weight HA) the carrier, adriamycin (ADM) paclitaxel (PTX) co-delivered drugs. The oHA-ss-PTX macromolecular prodrug was synthesized by introducing glutathione-stimuli-responsive disulfide bonds through chemical reactions. Then,...
The wood of Xanthoceras sorbifolium (XS) is used in ethnomedicine to treat bone pain. Osteoporosis among the causes that may result XS was extracted with supercritical CO2 obtain a fraction CDF and residue; residue by refluxing ethanol, ethanol extract concentrated supernatant (ES) precipitate (EP); major chemical components fractions were identified high-performance liquid chromatography-mass spectrometry. ES EP effectively counteracted dexa-methasone-induced delay calcification zebrafish...
To explore FDX1 methylation as a regulatory mechanism in the malignant phenotype of glioma, we screened for pathways involved through bioinformatic analysis, then proceeded with RIP and cell models to verify regulation RNAs mitophagy. We chose Clone Transwell assays evaluate glioma cells. MMP was detected by flow cytometry mitochondrial morphology observed TEM. also constructed animal study sensitivity cells cuproptosis. successfully identified signalling pathway: our model showed that C-MYC...