A5079887611- Osteoarthritis Treatment and Mechanisms
- Musculoskeletal pain and rehabilitation
- Orthopedic Surgery and Rehabilitation
- Shoulder Injury and Treatment
- Knee injuries and reconstruction techniques
- Total Knee Arthroplasty Outcomes
- Tendon Structure and Treatment
- Lower Extremity Biomechanics and Pathologies
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Rheumatoid Arthritis Research and Therapies
- Social Media in Health Education
- Inflammatory mediators and NSAID effects
- Foot and Ankle Surgery
- Hip disorders and treatments
- Health Literacy and Information Accessibility
- Behavioral Health and Interventions
- Pharmacological Effects of Medicinal Plants
- Pain Mechanisms and Treatments
- Diabetes Management and Education
- Dupuytren's Contracture and Treatments
- Healthcare Systems and Technology
- Laser Applications in Dentistry and Medicine
- Telemedicine and Telehealth Implementation
- Axon Guidance and Neuronal Signaling
- Statistical Methods in Clinical Trials
Royal North Shore Hospital
2017-2024
The University of Sydney
2017-2024
Institute for Musculoskeletal Health
2022-2024
Northern Sydney Local Health District
2018-2024
North Shore Hospital
2020
University of Calgary
2006-2007
Osteoarthritis (OA) is a chronic, disabling, and prevalent disorder. As there no cure for OA, long-term self-management paramount. Support groups (SGs) can facilitate among people living with OA. Understanding preferences in design features of SGs, including online SGs (OSGs), OA inform future development SG interventions this condition.The objective study was to investigate health care- information-seeking behavior, digital literacy, the The also explored perceived barriers enablers being...
A combination of conservative treatments is commonly used in clinical practice for thumb base osteoarthritis despite limited evidence this approach.To determine the efficacy a 6-week compared with an education comparator.Randomized, parallel trial 1:1 allocation ratio among people aged 40 years and older symptomatic radiographic community setting Australia.The intervention group (n = 102) received on self-management ergonomic principles, base-of-thumb splint, hand exercises, diclofenac...
Thumb-base osteoarthritis (OA) is a common cause of pain and disability This study aimed to investigate the associations musculoskeletal ultrasound OA pathologies with extent pain, function, radiographic scores, muscle strength in symptomatic thumb-base osteoarthritis. cross-sectional an ongoing clinical trial eligibility criteria including on Visual Analogue Scale (VAS) ≥40 (0 100 mm), Functional Index for Hand (FIHOA) ≥ 6 30) Kellgren Lawrence (KL) grade 2. The most side was scanned...
Objective. To evaluate the association of sleep quality, duration, and fatigue with hip pain exacerbations in persons symptomatic osteoarthritis (OA). Methods. Participants (n = 252) were followed for 90 days asked to complete online questionnaires at 10-day intervals (control periods). A exacerbation (case periods) was defined as an increase 2 points intensity compared baseline on a numeric rating scale (0–10). Subjective quality duration assessed using Pittsburgh Sleep Quality Index,...
The RADIANT study aimed to investigate the efficacy and safety of a complementary medicine supplement combination in people with hand osteoarthritis (HOA).This was an internet-based, double-blind, randomised, placebo-controlled trial. Participants aged over 40 years symptomatic HOA radiographic confirmation (Kellgren Lawrence grade ≥ 2) throughout Australia were recruited randomly assigned (1:1) receive either composed Boswellia serrata extract 250 mg/day, pine bark 100 methylsulfonylmethane...
Abstract Background The Patient Activation Measure (PAM-13) was developed using Rasch analysis to assess knowledge, skills and confidence in the management of one’s health. Previous studies report positive relationships between PAM-13 scores, self-management behaviours longitudinal health outcomes adults with chronic disease. There is little extant measurement property evidence for use specific osteoarthritis (OA) populations. This study tested properties people living hip knee OA. Methods...
Introduction Knee osteoarthritis (KOA) is a highly prevalent disabling joint disease. Intra-articular stem cell therapy increasingly being used for treating KOA with little high-quality evidence to support its use. The aim of this study investigate the efficacy, safety and cost-effectiveness allogeneic mesenchymal cells (Cymerus MSCs) symptomatic tibiofemoral improving knee structure over 24 months. Methods analysis Stem Cell injections relief strUctural improvement in people Tibiofemoral...
There is a pressing need to enhance osteoarthritis (OA) research find ways of alleviating its enormous individual and societal impact due the high prevalence, associated disability, extensive costs. Potential priorities initial rankings were pre-identified via surveys 1000Minds process by OA consumers community. The Summit was held decide key that match strengths expertise Australian community align with needs consumers. Facilitated breakout sessions conducted identify initiatives strategies...
To investigate the laser effect associated with stretching exercise on pain and functionality in patients knee osteoarthritis.A randomised controlled trial.Special Rehabilitation Services.We enrolled 215 osteoarthritis (430 knees were treated).Group Laser + Stretch (n = 43), Placebo 43) Control treated active exercises; placebo laser, control, respectively. Interventions conducted 3 times a week for 8 or 11 weeks.The primary outcome was change disability. Secondary outcomes included severity...
To evaluate the association between psychological factors and pain exacerbations in people with hip OA.Eligible participants symptomatic OA were instructed to complete online questionnaires every 10 days over a 90-day follow-up period. In addition, they required questionnaire whenever perceived experiencing exacerbation. Hip exacerbation was defined as an increase of 2 points intensity compared baseline on 11-point numeric rating scale (0-10). The Depression, Anxiety Stress Scale-21 Items,...
To develop a bank of text messages for lifestyle-based self-management intervention people with low back pain (LBP).
Objective To explore the person-level predictors of adherence to a step count intervention following total knee replacement (TKR). Design Prospective cohort study, nested within PATHway trial. Methods Participants who had recently undergone TKR were recruited from 3 rehabilitation hospitals in Sydney, Australia, for main Only data participants randomized group analyzed. (n = 51) received wearable tracker monitor number steps taken per day. Step was objectively measured at months as completed...
To test the effectiveness of a 32-week, stepped-care intervention on disease remission rates in overweight and obese patients with medial tibiofemoral osteoarthritis (OA) compared to controls.In this randomized controlled trial, eligible participants were ≥50 years age body mass index ≥28 kg/m2 radiographic evidence OA. Participants (n = 87) or control group 84). The received 2-step intervention. first step consisted an 18-week diet exercise program. second 4 treatment subgroups: 1)...
Digital technology represents an opportunity to improve outcomes following total knee replacement (TKR). Digitally delivered interventions have been shown be similar face-to-face and increase participation levels in people with osteoarthritis.To assess the effect of a digital package reducing pain compared usual care TKR.This randomized clinical trial recruited 102 adults after they received TKR 3 rehabilitation hospitals Sydney, Australia, between June 2020 July 2021.All participants...
Introduction The natural history of malignant pleural effusion is unknown. Palliative treatment reserved for symptomatic patients, but delaying until that time may make more difficult. This study aimed to determine the early, asymptomatic effusions in lung cancer patients. Methods Retrospective review clinical records and diagnostic imaging all patients presenting a new clinic during 3-month period. Patients with seen on chest x-ray or computed tomography scan not deemed require therapeutic...
To evaluate the association between hip injury/giving way and pain exacerbations in patients with symptomatic osteoarthritis (OA).We conducted an internet-based case-crossover study to assess injury giving for exacerbation. Eligible participants OA were followed up 90 days asked complete online questionnaires at baseline 10-day intervals (control periods). They also logged on web site episode of a exacerbation (case periods) defined as increase 2 points intensity compared rating numeric...
The objectives of this study are to ascertain the determinants quality life (QoL) and hand function among persons with osteoarthritis (OA) assess influence on QoL OA.Two hundred four participants in a clinical trial completed baseline assessment. Demographic, socioeconomic, (AqoL-4D), (Functional Index for Hand Osteoarthritis, FIHOA), pain assessment, radiographic characteristics were measured using standard methods. Univariate multivariate analyses performed evaluate potential...
To investigate the associations of ultrasound and radiographic features thumb-base osteoarthritis (OA) with pain hand function at baseline 12 weeks.Data from a randomized controlled trial conducted in participants symptomatic OA were analyzed. Participants who finished follow up included this secondary analysis. Pain assessed using self-reported measures. All underwent examinations for synovitis, power Doppler signal (PDS), osteophytes, radiography joint space narrowing (JSN), subchondral...