A5021307273- Pharmaceutical and Antibiotic Environmental Impacts
- Analytical chemistry methods development
- Environmental Toxicology and Ecotoxicology
- Mass Spectrometry Techniques and Applications
- Advanced Chemical Sensor Technologies
- Healthcare and Environmental Waste Management
- Water Quality and Pollution Assessment
- Metabolomics and Mass Spectrometry Studies
- Analytical Chemistry and Chromatography
- Forensic Fingerprint Detection Methods
- Geochemistry and Geologic Mapping
- Opioid Use Disorder Treatment
- Antibiotics Pharmacokinetics and Efficacy
- Mercury impact and mitigation studies
- Forensic Toxicology and Drug Analysis
- Heavy metals in environment
- Chemistry and Chemical Engineering
- Water Quality Monitoring and Analysis
- Computational Drug Discovery Methods
King's College London
2014-2019
Dublin City University
2013-2014
Galway-Mayo Institute of Technology
2013-2014
Abstract Background and aims Wastewater‐based epidemiology is an additional indicator of drug use that gaining reliability to complement the current established panel indicators. The this study were to: (i) assess spatial temporal trends population‐normalized mass loads benzoylecgonine, amphetamine, methamphetamine 3,4‐methylenedioxymethamphetamine (MDMA) in raw wastewater over 7 years (2011–17); (ii) address overall by estimating average number combined doses consumed per day each city;...
The first comprehensive assessment of 34 solid phase extraction sorbents is presented for organic explosive residues in wastewater prior to analysis with liquid chromatography-high resolution accurate mass spectrometry (LC-HRMS). A total 18 explosives were selected including nitramines, nitrate esters, nitroaromatics and peroxides. Three polymeric divinylbenzene-based found be most suitable one co-polymerised n-vinyl pyrrolidone offered satisfactory recoveries 14 compounds fortified...
Human pharmaceuticals (e.g. the lipid regulator gemfibrozil and non‐steroidal anti‐inflammatory drug diclofenac) are an emerging environmental threat in aquatic environment. This study aimed to evaluate sublethal effects of these two commonly found on protein profiles marine mussels ( Mytilus spp.). spp. was exposed environmentally relevant elevated concentrations (1 1000 µg/l respectively) both drugs for 14 days. In addition, were maintained seven days post treatment examine potential blue...
This study considers whether the current standard toxicokinetic methods are an accurate and applicable assessment of xenobiotic exposure in aquatic freshwater invertebrate. An vivo examined uptake elimination kinetics for eight pharmaceutical compounds amphipod crustacean, Gammarus pulex by measuring their concentrations both biological material medium over a 96 h period. Selected pharmaceuticals included two anti-inflammatories (diclofenac ibuprofen), beta-blockers (propranolol metoprolol),...
Abstract A new thin-film passive sampler is presented as a low resource dependent and discrete continuous monitoring solution for explosives-related vapours. Using 15 mid-high vapour pressure compounds probes, combinations of four thermally stable substrates six film-based sorbents were evaluated. Meta-aramid phenylene oxide-based materials showed the best recoveries from small voids (~70%). Analysis was performed using liquid chromatography-high resolution accurate mass spectrometry which...
Abstract The application of new sorbent-film coated passive samplers for capture bulk commercial and military explosives vapours in operationally relevant spaces such as luggage, rooms, vehicles shipping containers is presented. Samplers were easily integrated with in-service detection technologies little/no sample preparation required. Ethylene glycol dinitrate (EGDN) was detected within 4 h a container holding suitcase packed 0.2 kg Perunit 28E. Within 22,000 dm 3 room, 1 concealed...