Karen Arane

ORCID: 0000-0003-2603-253X
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About
Contact & Profiles
Research Areas
  • Streptococcal Infections and Treatments
  • Infectious Diseases and Tuberculosis
  • Restraint-Related Deaths
  • Neuroscience of respiration and sleep
  • Child Abuse and Related Trauma
  • Pediatric Pain Management Techniques
  • Otolaryngology and Infectious Diseases
  • School Health and Nursing Education
  • Pharmaceutical studies and practices
  • Escherichia coli research studies
  • Simulation-Based Education in Healthcare
  • Smoking Behavior and Cessation
  • Pain Management and Placebo Effect
  • Antibiotic Resistance in Bacteria
  • Heart Failure Treatment and Management
  • Medical Imaging and Pathology Studies
  • Radiopharmaceutical Chemistry and Applications
  • Immune Cell Function and Interaction
  • Carbon dioxide utilization in catalysis
  • Chemical Reactions and Mechanisms
  • Bacterial Identification and Susceptibility Testing
  • Obesity, Physical Activity, Diet
  • Chemical Reaction Mechanisms
  • Adipose Tissue and Metabolism
  • Coronary Artery Anomalies

Western University
2024

King Abdulaziz University
2024

University of Toronto
2024

Hospital for Sick Children
2012-2024

Icahn School of Medicine at Mount Sinai
2021

Tel Aviv University
2018

University of British Columbia
2017

Obesity is associated with chronic low-grade inflammation. Within adipose tissue of mice fed a high fat diet, resident and infiltrating macrophages assume pro-inflammatory phenotype characterized by the production cytokines which in turn impact on surrounding tissue. However, inflammation not restricted to fat-feeding responsible for significant increase cytokine expression muscle. Although skeletal muscle major disposer dietary glucose determinant glycemia, origin consequence development...

10.1186/1478-811x-10-30 article EN cc-by Cell Communication and Signaling 2012-10-19

Potentially nonadentate (N5O4) bifunctional chelator p-SCN-Bn-H4neunpa and its immunoconjugate H4neunpa-trastuzumab for 111In radiolabeling are synthesized. The ability of to quantitatively radiolabel 111InCl3 at an ambient temperature within 15 or 30 min, respectively, is presented. Thermodynamic stability determination with In3+, Bi3+, La3+ resulted in high conditional constant (pM) values. In vitro human serum assays have demonstrated both complexes over 5 days. Mouse biodistribution...

10.1021/acs.bioconjchem.7b00311 article EN Bioconjugate Chemistry 2017-07-06

Abstract Aim This study assessed the validity of using established Japanese risk scoring methods to predict intravenous immunoglobulin ( IVIG ) resistance Kawasaki disease in Israeli children. Methods We reviewed medical records 282 patients (70% male) with from six centres between 2004 and 2013. Their mean age was 2.5 years. The scores were calculated Kobayashi, Sano Egami analysed determine whether a higher score predicted this population. Factors that lack response initial dose...

10.1111/apa.14418 article EN Acta Paediatrica 2018-05-24

We report the detection of OXA-181 carbapenemase in an azithromycin-resistant Shigella spp. bacteria immunocompromised patient. The emergence raises concerns about global dissemination carbapenem resistance Enterobacterales and its implications for treatment infections caused by bacteria.

10.3201/eid3005.231558 article EN cc-by Emerging infectious diseases 2024-04-25

<strong>Background:</strong> Weight is a crucial metric in the optimal care of pediatric patients inpatient setting. A patient’s weight not only necessary for appropriate medication dosing, but also often an indicator fluid and nutritional status. As such, having documented integral to clinical decision making, failure obtain daily measurements when needed can result delays treatment discharge plans. The importance monitoring as well challenges surrounding good adherence orders has long been...

10.29024/jsim.97 article EN cc-by Journal of Scientific Innovation in Medicine 2021-01-01
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