A5004794214- Natural Antidiabetic Agents Studies
- Advanced Glycation End Products research
- Diabetes and associated disorders
- Antimicrobial Peptides and Activities
- Hepatitis Viruses Studies and Epidemiology
- Immune Response and Inflammation
- Preterm Birth and Chorioamnionitis
- Hepatitis B Virus Studies
- Diet, Metabolism, and Disease
Universidade Federal de Mato Grosso
2015-2024
This study aims to evaluate the phytochemical properties of Bauhinia holophylla (Bong.) Steud leaf extract, and their impact on maternal reproductive fetal development in diabetic rats. For this, adult female Wistar rats (100 days life) received streptozotocin (40 mg/Kg, intraperitoneal) for induction diabetes, were mated distributed into four groups: Nondiabetic; Nondiabetic given B. holophylla; Diabetic; Diabetic holophylla. The plant extract was by gavage at increasing doses: 200, 400,...
Materials and methods Diabetes was induced by streptozotocin (40 mg/kg) in virgin female Wistar rats. After diabetes status confirmation, rats were mated. The pregnant diabetic divided four experimental groups (n minimum=12 animals/group): Non-diabetic; Non-diabetic Treated; Diabetic Treated. Oral administration of leaves aqueous extract Bauhinia holophylla given to non-diabetic at increasing doses: 200mg/kg between day 0 7 pregnancy, 400 mg/kg 8 14 800 15 21. On 21 all anesthetized killed,...