A.V. Polunina

ORCID: 0000-0003-2613-1503
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About
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Research Areas
  • Gut microbiota and health
  • Long-Term Effects of COVID-19
  • COVID-19 Clinical Research Studies
  • SARS-CoV-2 and COVID-19 Research
  • Obesity, Physical Activity, Diet
  • Birth, Development, and Health
  • COVID-19 Prevention and Impact
  • Medical and Biological Ozone Research
  • Clostridium difficile and Clostridium perfringens research
  • Infant Development and Preterm Care
  • Immune responses and vaccinations
  • Pediatric Pain Management Techniques
  • Dental Research and COVID-19

Saint Petersburg State Pediatric Medical University
2023-2024

Summary Post- COVID syndrome refers to the long-term consequences of a new coronavirus infection COVID-19, which includes set symptoms that develop or persist after COVID-19. Symptoms gastrointestinal disorders in post- syndrome, due chronic infl ammation, organ damage, prolonged hospitalization, social isolation, and other causes, can be persistent require multidisciplinary approach. The presented clinical practice guidelines consider main preventive therapeutic diagnostic approaches...

10.31146/1682-8658-ecg-208-12-4-68 article EN cc-by Experimental and Clinical Gastroenterology 2023-05-20

Background: studying the consequences of novel coronavirus infection is currently relevant. Many observations demonstrate that SARS- CoV-2 affects gastrointestinal tract, gut microbiota composition, and intestinal permeability. Aim: to assess whether Maxilac® Baby synbiotic effects qualitative quantitative composition permeability in children aged 3–14 with mild-to-moderate COVID-19. Patients Methods: an open, observational, prospective, single-center study minimal intervention was...

10.32364/2618-8430-2023-6-3-10 article EN Russian Journal of Woman and Child Health 2023-01-01

This review summarizes relevant scientific literature analyzing the lung-gut axis and its association with coronavirus infection (COVID-19), lesions to gastrointestinal tract caused by this infection, state of microbiome. Approximately 20%–50% COVID-19 patients have such symptoms as nausea, vomiting, diarrhea, well SARS-CoV-2 RNA detected in their feces. Therefore, investigation virus effect on commensal flora is important not only for research purposes, but clinical practice, since...

10.20953/1729-9225-2021-1-91-96 article EN Infekcionnye bolezni 2021-01-01

Fecal zonulin is currently used as a biomarker of intestinal permeability. Objective. To assess the state permeability in novel coronavirus infection (COVID-19) children based on determination fecal levels. Patients and methods. levels were assessed 35 with COVID-19, which was mild most them. sampling performed at time diagnosis 14 days after start observation. then randomized into two groups. Group 1 (study, n = 19) received Maxilac® Baby synbiotic (2 sachets once day) for month, group 2...

10.20953/1729-9225-2022-3-35-40 article EN Infekcionnye bolezni 2022-01-01

The new coronavirus infection (COVID-19) that emerged in 2019 is a caused by the SARS-CoV-2 virus. Although predominantly affects respiratory system, numerous studies suggest significant gastrointestinal involvement COVID-19, particularly children. Aim. To evaluate effect of synbiotic Maxilac® children with COVID-19 after antibacterial therapy (ABT). Materials and methods. A clinical post-approval open-label observational prospective single-center study minimal intervention was conducted....

10.26442/26586630.2024.2.202935 article EN cc-by-nc-sa Pediatrics Consilium Medicum 2024-10-16

Введение. Несмотря на то что пандемия новой коронавирусной инфекции окончилась, эта проблема не утратила своей актуальности. В России за все время инфекцией заразились 24645303 человека. По состоянию ноябрь 2024 года в Российской Федерации данный вирус идентифицировали у 35689 человек. COVID-19 настоящее подвергается общим инфекционным законам, таким как эпидемиология и сезонность. Вклад распространенность этой вносит способность вируса SARS-CoV-2 к трансмиссии быстрой мутации. Цель —...

10.56871/cmn-w.2024.57.85.018 article RU Children s medicine of the North-West 2024-12-03
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