A5044887003- Antibiotic Resistance in Bacteria
- Bacterial biofilms and quorum sensing
- Vibrio bacteria research studies
- Antibiotic Use and Resistance
- Mycobacterium research and diagnosis
- Salmonella and Campylobacter epidemiology
- Tuberculosis Research and Epidemiology
- Cystic Fibrosis Research Advances
- Antimicrobial Resistance in Staphylococcus
- Healthcare Regulation
- Infections and bacterial resistance
- Aquaculture disease management and microbiota
- Tracheal and airway disorders
- Pneumonia and Respiratory Infections
- Milk Quality and Mastitis in Dairy Cows
- Respiratory viral infections research
- Brucella: diagnosis, epidemiology, treatment
- Pharmaceutical and Antibiotic Environmental Impacts
Ministério da Saúde
2012-2025
Universidade do Estado do Pará
2022-2025
Amazon (United States)
2025
Instituto Evandro Chagas
2012-2025
Amazon Research Foundation
2025
A One Health approach for antimicrobial resistance must integrate whole-genome sequencing surveillance data of critical priority pathogens from human, animal and environmental sources to track hot spots routes transmission developing effective prevention control strategies. As part the Grand Challenges Explorations: New Approaches Characterize Global Burden Antimicrobial Resistance Program, we present genomic WHO carbapenemase-resistant, ESBL-producing, and/or colistin-resistant Escherichia...
Abstract Background Childhood pneumonia and bronchiolitis is a leading cause of illness death in young children worldwide with Respiratory Syncytial Virus (RSV) as the main viral cause. RSV has been associated annual respiratory disease outbreaks bacterial co-infection also reported. This study first epidemiological hospitalized community-acquired (CAP) Belém city, Pará (Northern Brazil). Methods With objective determining prevalence infection evaluating patients’ clinical features, we...
Bedaquiline, an antimicrobial used to treat drug-resistant tuberculosis (DR-TB), was introduced in Brazil October 2021. Monitoring the emergence and transmission of DR-TB is crucial for implementing public health control spread DR strains Mycobacterium . To measure its impact on multi-drug treatment scheme state Pará, we aimed conduct genomic surveillance after bedaquiline Brazil. Individuals treated between 2021 December 2022, reference hospital cases from were included study. Clinical...
Pseudomonas aeruginosa is a major pathogen in cystic fibrosis (CF), where chronic and intermittent infections significantly affect patient outcomes. This study aimed to investigate the molecular epidemiology of P. CF patients from Brazilian Amazon, focusing on genotypic diversity, resistance profiles, virulence factors. A cross-sectional included 72 isolates 44 treated at regional reference center between 2018 2019. Antimicrobial susceptibility patterns were determined using VITEK-2 system...
Pseudomonas aeruginosa is an opportunistic pathogen causing different types of infections, particularly in intensive care unit patients. Characteristics that favor its persistence artificial environments are related to high adaptability, wide arsenal virulence factors and resistance several antimicrobial classes. Among the determinants, T3SS stands as most important due clinical impact exoS exoU genes patient's outcome. The molecular characterization P. isolates helps comprehension...
Pseudomonas aeruginosa is a high-priority bacterial agent that causes healthcare-acquired infections (HAIs), which often leads to serious and poor prognosis in vulnerable patients. Its increasing resistance antimicrobials, associated with SPM production, case of public health concern. Therefore, this study aims determine the antimicrobial resistance, virulence, genotyping features P. strains producing SPM-1 Northern region Brazil. To presence virulence genes, PCR technique was used. For...
Pseudomonas aeruginosa appears as the main pathogen in cystic fibrosis (CF) involved recurrent pneumonia and pulmonary exacerbations. The type III secretion system (T3SS) is one of its determinants virulence associated with poor clinical progression increased mortality. This study determined relationship features patients CF P. T3SS virulotypes.From January 2018 to March 2019, were isolated from sputum and/or oropharyngeal swabs. markers (exoS, exoU, exoT exoY) detected by PCR. Clinical...
Carbapenem resistance among
Typhoidal salmonellosis is a global public health problem occurring in developing endemic regions. In Brazil, cases are mostly registered the North and Northeast Molecular characterization of strains important to understand epidemiology disease infections design control strategies. The present study retrospectively evaluates genotyping features sporadic outbreak-related Salmonella Typhi isolates from Brazilian region. Bacterial were recovered blood rectal swab patients states Acre Pará,...
A pandemia COVID-19 favoreceu a disseminação de bactérias multirresistentes no ambiente hospitalar levando ao aumento das infecções relacionadas à assistência saúde (IRAS) principalmente aquelas causadas por produtoras carbapenemases. Com introdução novos antimicrobianos, identificação do tipo carbapenemase torna-se fundamental para orientação da conduta terapêutica. Em contrapartida, detecção oportuna produção carbapenemases ainda é uma dificuldade em muitos hospitais. Este estudo avaliou...
There are several infectious diseases that affect equines and can cause large economic losses in this sector damage to animal welfare. In species, abscessing lesions of a purulent character preferentially the withers strongly suggestive brucellosis. However, few studies have been carried out on disease making its identification control difficult due lack standardization interpretation results. Therefore, samples whole blood, serum secretion were collected from three horses. The animals came...