David Nicholson

ORCID: 0000-0003-2653-9349
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About
Contact & Profiles
Research Areas
  • Marine and coastal ecosystems
  • Oceanographic and Atmospheric Processes
  • Marine Biology and Ecology Research
  • Ocean Acidification Effects and Responses
  • Atmospheric and Environmental Gas Dynamics
  • Methane Hydrates and Related Phenomena
  • Isotope Analysis in Ecology
  • Mycobacterium research and diagnosis
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Tuberculosis Research and Epidemiology
  • Arctic and Antarctic ice dynamics
  • Environmental Monitoring and Data Management
  • Poisoning and overdose treatments
  • Respiratory Support and Mechanisms
  • Asthma and respiratory diseases
  • Inhalation and Respiratory Drug Delivery
  • Geology and Paleoclimatology Research
  • Marine and fisheries research
  • Pleural and Pulmonary Diseases
  • Migraine and Headache Studies
  • Antibiotics Pharmacokinetics and Efficacy
  • Atmospheric chemistry and aerosols
  • Venous Thromboembolism Diagnosis and Management
  • Pharmaceutical studies and practices
  • Pericarditis and Cardiac Tamponade

Woods Hole Oceanographic Institution
2016-2025

Marine Biological Laboratory
2022

University of Virginia
2019

University of Hawaiʻi at Mānoa
2015-2018

University of Washington
2004-2018

Oceanography Society
2018

Stanford Health Care
2017

University of Hawaii System
2015

Stanford University
2006-2008

Cleveland Clinic
2004

Sustained ocean time series are critical for characterizing marine ecosystem shifts in a of accelerating, and at times unpredictable, changes. They represent the only means to distinguish between natural anthropogenic forcings, best tools explore causal links implications human communities that depend on resources. Since inception sustained observations, have withstood many challenges, most prominently availability uninterrupted funding retention trained personnel. This OceanObs'19 review...

10.3389/fmars.2019.00393 article EN cc-by Frontiers in Marine Science 2019-07-12

We compared the accuracy and precision of low-dose insulin administration using various devices including, for first time, an pump. dispensed 1, 2, 5 unit(s) soluble (100 units/mL) 15 times each from a NovoPen (3.0 mL), BD-Mini Pen (1.5 Humalog units/mL), 30G Precision Sure-Dose Insulin Syringes, 3OG BD Ultra-Fine II Short Needle H-TRON-plus V100 Each dose was weighed on analytical scale, delivered target doses were compared. Accuracy defined by absolute percent difference dose. as group...

10.1177/000992280404300109 article EN Clinical Pediatrics 2004-01-01

Seagliders, deployed through most of 2005 in the subtropical North Pacific gyre, made measurements temperature, salinity, and dissolved oxygen to quantify net community production (NCP) at Station A Long‐ Term Oligotrophic Habitat Assessment (ALOHA) Hawaii Ocean Time‐series (HOT) using an mass balance approach. ‘bowtie’‐shaped pattern, 50 km by size was repeatedly traversed two week intervals with goal observing influence Rossby waves eddies on productivity study region. region cause a...

10.4319/lo.2008.53.5_part_2.2226 article EN Limnology and Oceanography 2008-09-01

Abstract We present a year‐round time series of dissolved methane (CH 4 ), along with targeted observations during ice melt CH and carbon dioxide (CO 2 ) in river estuary adjacent to Cambridge Bay, Nunavut, Canada. During the freshet, concentrations ice‐covered were up 240,000% saturation 19,000% saturation, respectively, but quickly dropped by >100‐fold following melt. Observations robotic kayak revealed that river‐derived CO transported rapidly ventilated atmosphere once cover...

10.1029/2020gl087669 article EN publisher-specific-oa Geophysical Research Letters 2020-04-23

Abstract Approximately half of global primary production occurs in the ocean. While large‐scale variability net (NPP) has been extensively studied, ocean gross (GPP) thus far received less attention. In this study, we derived two satellite‐based GPP models by training machine learning algorithms (Random Forest) with light‐dark bottle incubations (GPP LD ) and triple isotopes dissolved oxygen 17Δ ). The predict GPPs 9.2 ± 1.3 × 10 15 15.1 1.05 mol O 2 yr −1 for , respectively. projected...

10.1029/2020gb006718 article EN Global Biogeochemical Cycles 2021-01-15

The goal of the EXport Processes in Ocean from RemoTe Sensing (EXPORTS) field campaign is to develop a predictive understanding export, fate, and carbon cycle impacts global ocean net primary production. To accomplish this goal, observations export flux pathways, plankton community composition, food web processes, optical, physical, biogeochemical (BGC) properties are needed over range ecosystem states. Here we introduce first EXPORTS deployment Station Papa Northeast Pacific during summer...

10.1525/elementa.2020.00107 article EN cc-by Elementa Science of the Anthropocene 2021-01-01

Enzyme-labeled fluorescence (ELF) and bulk alkaline phosphatase (AP) activity enzyme assays were used to evaluate the phosphorus (P) status of phytoplankton communities in San Francisco Monterey bays. Both regions exhibit spatial temporal variability AP with maximum activities during early spring summer periods high biological productivity. ELF analysis revealed pronounced differences makeup organisms responsible for these two environments. In Bay dinoflagellates are activity. Diatoms...

10.4319/lo.2006.51.2.0874 article EN Limnology and Oceanography 2006-03-01

We describe a method for determining net annual biological oxygen production in the euphotic zone of ocean using remote situ measurements and nitrogen gas. Temperature, salinity, oxygen, total dissolved gas pressure were measured every 2 hours at 10‐m depth on mooring Hawaii Ocean time series during year 2005. Since N is effectively inert to processes it can be used as tracer physical mechanisms affecting O concentration an upper model concentrations. determine surface mixed layer 4.8 ± 2.7...

10.1029/2007gb003095 article EN Global Biogeochemical Cycles 2008-08-23

Abstract We measured triple oxygen isotopes and oxygen/argon dissolved gas ratios as nonincubation‐based geochemical tracers of gross production (GOP) net community (NCP) on 16 container ship transects across the North Pacific from 2008 to 2012. estimate rates efficiency biological carbon export throughout full annual cycle basin (35°N–50°N, 142°E–125°W) by constructing mixed layer budgets that account for physical influences these tracers. During productive season spring fall, GOP NCP are...

10.1002/2015gb005318 article EN Global Biogeochemical Cycles 2016-02-01

Abstract The expansion of autonomous observation platforms offers vast opportunities for analyzing ocean ecosystems and their role in carbon export. As part the EXport Processes Ocean from RemoTe Sensing campaign, we autonomously measured productivity regimes two contrasting end‐member ecosystem states. first campaign occurred subpolar North Pacific near Station Papa (Site 1), characterized by iron limitation a highly regenerative regime. second captured springtime bloom Atlantic 2), which...

10.1002/lno.70002 article EN cc-by Limnology and Oceanography 2025-02-28

The subpolar North Atlantic is a known hotspot for anthropogenic carbon and oxygen uptake, however the detailed pathways dissolved gasses into deep remain poorly understood. While it clear that high-oxygen waters formed by convection in basin interiors are exported southward boundary currents, has also been hypothesized significant water mass transformation associated gas exchange occurs near or within currents themselves. Here we present novel year-round observations mounted on Overturning...

10.5194/egusphere-egu25-13025 preprint EN 2025-03-15

Formed by deep convection in the Nordic Seas, cold, oxygen-rich Denmark Strait Overflow Water (DSOW) is densest water mass lower limb of Atlantic Meridional Overturning Circulation (AMOC). As DSOW spreads southward from into Irminger Sea, overflow entrains ambient masses. This entrainment critical for transfer climate signals and biogeochemical tracers surface to ocean. Although impact on properties immediate vicinity (< 100 km downstream sill) has been studied extensively, dynamics...

10.5194/egusphere-egu25-13071 preprint EN 2025-03-15

Blood concentrations of theophylline were measured in a variety conditions to determine the effective and safe dose for intravenous therapy. After single dose, concentration of...

10.1164/arrd.1973.108.2.241 article EN PubMed 1973-08-01

The triple oxygen isotopic composition of dissolved ( 17 Δ) is a promising tracer gross productivity P ) in the ocean. Recent studies have inferred high and variable ratio to 14 C net primary (12–24 h incubations) (e.g., :NPP( C) 5–10) using Δ method, which implies very low efficiency phytoplankton growth rates relative photosynthetic rates. We added isotopes one‐dimensional mixed layer model assess role physical dynamics potentially biasing estimates method at Bermuda Atlantic Time‐series...

10.1029/2010jc006856 article EN Journal of Geophysical Research Atmospheres 2012-03-30

Abstract Using autonomous underwater gliders, we quantified diurnal periodicity in dissolved oxygen, chlorophyll, and temperature the subtropical North Pacific near Hawaii Ocean Time‐series (HOT) Station ALOHA during summer 2012. Oxygen optodes provided sufficient stability precision to quantify diel cycles of average amplitude 0.6 µmol kg −1 . A theoretical curve was fit daily observations infer an mixed layer gross primary productivity (GPP) 1.8 mmol O 2 m −3 d Cumulative net community...

10.1002/2015gl063065 article EN cc-by-nc-nd Geophysical Research Letters 2015-04-29

Abstract The triple oxygen isotopic composition of dissolved ( 17 Δ dis ) was added to the ocean ecosystem and biogeochemistry component Community Earth System Model, version 1.1.1. Model simulations were used investigate biological physical dynamics assess its application as a tracer gross photosynthetic production (gross GOP )) O 2 in mixed layer. model reproduced large‐scale patterns found observational data across diverse biogeographical provinces. Mixed layer performance best Pacific...

10.1002/2013gb004704 article EN Global Biogeochemical Cycles 2014-04-29

The biological pump plays a key role in the global carbon cycle by transporting photosynthetically fixed organic into deep ocean, where it can be sequestered from atmosphere over annual or longer time scales if exported below winter ventilation depth.In subpolar North Atlantic, sequestration via is influenced two competing forces: spring diatom bloom that features large, fast-sinking biogenic particles, and mixing requires particles to sink much further than other ocean regions escape...

10.5670/oceanog.2018.108 article EN cc-by Oceanography 2018-02-09

Coastal ecosystems host high levels of primary productivity leading to exceptionally dynamic elemental cycling in both water and sediments. In such environments, carbon is rapidly cycled rates burial as organic matter and/or loss the atmosphere laterally coastal ocean simpler forms, dioxide (CO2) methane (CH4). To better understand across these heterogeneous new technologies beyond discrete sample collection analysis are needed characterize spatial temporal variability. Here, we describe...

10.1021/acs.est.8b04190 article EN Environmental Science & Technology 2018-10-25

Abstract Diel variations in oxygen concentration have been extensively used to estimate rates of photosynthesis and respiration productive freshwater marine ecosystems. Recent improvements optical sensors now enable us use the same approach metabolic oligotrophic waters that cover most global ocean for measurements collected by autonomous underwater vehicles. By building on previous methods, we propose a procedure from vertically resolved diel concentration. This involves isolating variation...

10.1002/lom3.10340 article EN cc-by Limnology and Oceanography Methods 2019-11-20

Bacterioplankton play a central role in carbon cycling, yet their relative contributions to production and removal can be difficult constrain. As part of the Export Processes Ocean from RemoTe Sensing (EXPORTS) program, this study identifies potential influences bacterioplankton community dissolved organic matter (DOM) composition on cycling at Station Papa August 2018. Surface (5–35 m) rates stocks spanned 2- 3-fold range over 3-week cruise correlated positively with DOM degradation state,...

10.1525/elementa.2022.00095 article EN cc-by Elementa Science of the Anthropocene 2023-01-01

Biogeochemical-Argo floats are collecting an unprecedented number of profiles optical backscattering measurements in the global ocean. Backscattering (BBP) data crucial to understanding ocean particle dynamics and biological carbon pump. Yet, so far, no procedures have been agreed upon quality control BBP real time.Here, we present a new suite real-time quality-control tests apply them current Argo dataset. The were developed by expert users managers implemented on snapshot entire...

10.12688/openreseurope.15047.2 article EN cc-by Open Research Europe 2023-05-30
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