Phosfolan, chlorpyrifos, and stirophos when applied to white mice at sublethal doses did not induce any delayed neurotoxic effect. On the other hand, Leptophos EPN administered orally or lethal levels clearly produced a ataxia in treated mice. The five tested organophosphorus insecticides were compared for their ability inhibit cholinesterase, esterases monoamine oxidase. I50 values estimated each case. results revealed that all compounds inhibitors of but only shown be potent both esterase...

Two spraymen working in public health occupations Alexandria, Egypt, experienced acute toxicity resulting from exposure to diazinon. Symptomatology was similar that previously reported for parathion or other organophosphorus insecticides. Plasma and red blood cell cholinesterase activity values were determined samples obtained both individuals at various times after the incident. Cholinesterase showed a marked reduction up 18 days exposure. Blood recovered approximately 90% of normal level...

Cyanofenphos (surecide)(R), 25% E.C., O-ethyl O-(4-cyanophenyl) phenylphosphonothioate, was orally administered to one year old lambs at sublethal doses of 1 mg, 2 mg and 4 active ingredient kg-1 day-1 for time intervals 60, 45 30 days respectively. Irreversible paralytic ataxia symptoms delayed neuropathy appeared about 80, 50 In weekly blood samples, AChE (acetylcholine-sterase) MAO (monoamine oxidase) activities were inhibited depending upon level dosing interval. However no significant...

Five organophosphorous insecticides: Leptophos, EPN, Cyanofenphos, trichloronate and salithion proved to cause irreversible ataxia not only chicken but also mice sheep. TOCP was included as a reference. Cyanofenphos blocked the catecholamine B-receptor binding activity with 3H-norepinephrine at level similar that of specific inhibitor propranolol in mouse heart preparation. In lamb preparation, more sensitive than propranolol. The six compounds their oxons were screened for in-vitro...

Abstract LD50 and in vitro ChE I50. values of Chlorpyrifos, Leptophoa, Phoafolan, Stirophos against white mice showed that the formulated insecticides were higher their mammalian toxicity than corresponding technical materials. Pre‐treatment with a sublethal dose Phosfolan potentiated post‐treatment Stirophos, Phosfolan, or but antagonized post—treatment Leptophos. On other hand, pretreatment doses Leptophos resulted potentiation decreased Chlorpyrifos Pretreatment by synergized vivo...

The effect of the 1/10 application rates either copper sulfate, temephos, glyphosate, or bifenthrin on some biochemical and genotoxic markers Egyptian toads, Sclerophrys regularis, exposed for 96 hours under conditions similar to real situation was investigated. results illustrated that , brain acetylcholinesterase (AChE) significantly inhibited following temephos treatment, while enzyme activities markedly increased glyphosate exposure. Liver glutathione-S-transferase (GST) activity sulfate...

Brain tissue samples of mice (7.6 g from 25 mouse brains and lamb (25 g) were homogenized subcellular fractions prepared in order to assay the distribution neurotoxic esterase (NTE) activity. The specific inhibitor, N,N-diisopropylphosphorodiamidic fluoride (mipafox) was synthesized purified. Maximum activity NTE reached microsomal fraction (110,000 while enzyme soluble extremely low. This mammal is an original contribution. suggested be a more reliable source for highest NTE. brain much...

Abstract Tri‐ o ‐cresyl phosphate (TOCP) is used commercially as a plasticizer and flame retardant. The disposition, metabolism, elimination transplacental uptake of [phenyl‐U‐ 14 C]TOCP and/or its metabolites, in pregnant non‐pregnant mice, were examined. Pregnant (18th‐day gestation) non‐pregnant, ICR mice given an i.v. dose [ (557 μCi kg −1 ; Specified activity 4.83 μmol ). At various time intervals (1, 24, 48 72 h) the animals processed for whole‐body autoradiography (WBA). Over h...

The nematicidal activity of dried ground seeds Ammi majus, Matricaria chamomilla, Ricinus communis, Brassica alba, B. oleracea, Peganum harmala, Solanum nigrum, Raphanus sativus and Eucalyptus sp. was assessed against the root-knot nematode, Meloidogyne incognita, infecting tomato in a glasshouse. powdered tested plants were incorporated into soil at rate 5 g/kg their compared with that synthetic nematicide carbofuran 0.01 g a.i./kg. effects treatments on growth also examined. populations M....

The effect of water treatment processes on the levels chlorinated hydrocarbons(α, β, γ-HCH, DDE and P,P'-DDT) chlorophenols(2,4-D; 2,3-D; 2,3,4-T; 2,4,5-T; 2,3,4,6-Tet. PCP) collected from Bab-Shark Abo-Hormos were analysed by GLC. results showed that steps did not significantly reduce or remove HCH treated water. This was shown high content in when compared with raw However, other compounds, like P,P'-DET, undetected after treatment. data chlorophenols 2,4-D slightly reduced purification,...

The ameliorating effect of 150 mg/kg b.w. Nacetylcysteine (NAC) against the oral administration 7.88 (1/25 LD50) or 202.07 (1/10 mg/kg/day for 14 days chlorpyrifos-ethyl (CPF-E) and chlorpyrifosmethyl (CPF-M), respectively, was investigated using neurobehavioral biochemical markers this toxicity.Neurobehavioral tests; open field test (OFT), hole-board (HBT), light/dark box (LDBT) elevated plus maze (EPM) showed increase frequency exploration, low level anxiety locomotor in rats treated with...

Background: Polycystic ovarian syndrome (PCOs) is a common endocrine disorder that associated with negative metabolic, reproductive, endocrine, and psychological consequences among women in reproductive age.Many girls chronic menstrual irregularities could have PCOs.This study aimed to assess the levels of knowledge for female nursing students regarding polycystic syndrome, at south valley university.Subjects Methods: A descriptive cross sectional design was used achieve objective this...