A5062815898- Colorectal Cancer Treatments and Studies
- Cancer Treatment and Pharmacology
- Gastric Cancer Management and Outcomes
- Lung Cancer Treatments and Mutations
- Pancreatic and Hepatic Oncology Research
- Genetic factors in colorectal cancer
- Colorectal Cancer Screening and Detection
- Renal cell carcinoma treatment
- CNS Lymphoma Diagnosis and Treatment
- Lung Cancer Diagnosis and Treatment
- Lymphoma Diagnosis and Treatment
- HER2/EGFR in Cancer Research
- Cancer Genomics and Diagnostics
- Breast Lesions and Carcinomas
- Lung Cancer Research Studies
- Breast Cancer Treatment Studies
- Chronic Lymphocytic Leukemia Research
- Hepatocellular Carcinoma Treatment and Prognosis
- Telomeres, Telomerase, and Senescence
- Colorectal Cancer Surgical Treatments
- Economic and Financial Impacts of Cancer
- Colorectal and Anal Carcinomas
- Glioma Diagnosis and Treatment
- Advanced Breast Cancer Therapies
- Global Cancer Incidence and Screening
Minia University
2015-2025
Riyadh Armed Forces Hospital
2021-2025
Misr University for Science and Technology
2025
King Saud University
2025
Assiut University
2025
Prince Mohammed bin Abdulaziz Hospital
2025
Children Cancer Hospital
2025
Cairo University
2019
King Fahad Hospital Jeddah
2012-2018
Minia University Hospital
2010-2018
Background The 5-fluorouracil (5-FU), capecitabine-based long-course or short-course radiotherapy (SCRT) eventually preceded followed by induction consolidation chemotherapy (CT) and resection represents the preferred regimen for treatment of locally advanced rectal cancer (LARC). This study aims to report our experience as a large medical center in Saudi Arabia, with efficacy radiation therapy oxaliplatin-based CT achieving pathologic complete response (pCR) patients LARC. Materials methods...
691 Background: Pancreatic ductal adenocarcinoma (PDAC) has dismal clinical outcomes, even with existing treatment regimens. This study evaluates the characteristics and outcomes of patients locally advanced unresectable or de-novo metastatic PDAC in Saudi Arabia to provide real-world data that can be compared international benchmarks. Methods: is a retrospective, multicenter study. Patients diagnosed between January 2015 November 2023 were included. Data collected from 10 oncology centers...
Aims: To delineate the histopathological pattern of prostate diseases and to highlight age variations in specific antigen (PSA) values features. Materials Methods: A retrospective review was made all biopsy reports seen between January 2006 December 2013 at King Fahad Hospital, Madinah, Saudi Arabia. Prostate lesions were tabulated classified into benign malignant groups. Histological scoring adenocarcinomas accomplished using Gleason system. PSA correlated with scores. Results: Of 417...
Hepatocellular carcinoma (HCC) is the sixth most common type of cancer in world associated with high morbidity and mortality. Despite being a significant healthcare burden there limited information on unmet needs current treatment practices for intermediate advanced-stage HCC Saudi Arabia. This article analyzes gaps provides expert consensus management strategies unresectable A pre-meeting online questionnaire, comprising 20 objective questions about landscape diagnosis Arabia, was...
Metastasis to the breast from extra-mammary tumors is rare with only a few sporadic cases reported. We present 58-year-old female patient diagnosed renal cell carcinoma. Five years ago she had radical nephrectomy and was free of disease, then discovered solitary mass following self-examination. The presented clinic for evaluation whereupon identified on physical radiological examinations. Fine needle aspiration diagnostic metastatic carcinoma subsequent imaging studies demonstrated multiple...
<b>Background:</b> Lung cancer management is getting more complex due to the rapid advances in all aspects of diagnostic and therapeutic options. Developing guidelines critical help practitioners provide standard care.<br><b>Methods:</b> The Saudi Cancer Guidelines Committee (SLCGC) multidisciplinary members from different specialties various regions healthcare sectors country reviewed updated lung with appropriate labeling level evidence. Supporting documents professionals were...
Metastatic colorectal cancer (mCRC) is a significant global health burden. This retrospective study compared the effectiveness of trifluridine/tipiracil (FTD/TPI), regorafenib, and chemotherapy rechallenge for third-line mCRC treatment.
Mutations in codons 12/13 of K-ras exon 2 are associated with reduced benefit from anti-epidermal growth factor receptor antibody treatment for metastatic colorectal cancer (CRC). Here, we evaluated the frequency mutations and their relationship clinicopathological features outcomes Saudi Arabian patients CRC. The genetic status was determined 300 diagnosed Clinical information collected retrospectively. wild-type 58% mutated 42% tumors. Most were at codon 12 (89%) metastasis [odds ratio...
Purpose: Radiotherapy with concurrent temozolomide (TMZ), followed by 6 cycles of adjuvant TMZ, is the standard care for newly diagnosed Glioblastoma Mulltiforme (GBM). However tumor progression role median survival almost 14 months. With lack effective second line chemotherapy, many physicians and some guidelines advocate prolonged use TMZ more than We conduct this study to test efficacy protracted conventional dose over doses TMZ. Material Methods: This phase II trial enrolled patients as...
Gastric cancer (GC) ranks as the fifth most prevalent and fourth deadliest worldwide. In Middle East North Africa (MENA) region, GC represents about 4.8% of cases with more than 35,000 new in 2020. To strengthen improve management this a group MENA experts field developed first consensus recommendations for advanced GC. A total 28 statements were drafted, discussed voted on, using modified Delphi process, during virtual meeting. The addressed areas epidemiology, biomarkers treatment.
Lapatinib alone or in combination with other agents, mostly capecitabine is used for patients advanced/metastatic HER2 positive breast cancer (HER2(+)BC) after progression on trastuzumab based therapy. Here we report our experience lapatinib therapy this setting.67 consecutive received 58 (86.6%) + (LC), 7 (10.4%) agents and 2 (3.0%) as single agent lapatinib. Data was collected from patients' records retrospectively.Objective response to 64 evaluable 64.0% all who LC. Median free survival...
e15545 Background: Significant proportion of metastatic colorectal cancer (mCRC) patients receive systemic therapy beyond second line. This study aims to assess predictors survival outcome in treated with TAS 102/bevacizumab compared TAS102 alone 2nd Methods: In this retrospective study, we assessed mCRC TAS102/bevacizumab or line 4 institutes Saudi Arabia from January 2020 December 2022. We checked progression-free (PFS) and overall (OS) the group different parameters that may affect...
e16348 Background: Pancreatic Cancer is one of the leading causes cancer death in Saudi Arabia. Surgery mainstay treatment resectable non-metastatic cases. Working on improving resectability rate to achieve R0 resection standard care. Methods: Unresectable cases pancreatic adenocarcinoma seen from 2004 till 2018 three hospitals Arabia were reviewed know conversion unresectable or borderline after neoadjuvant chemotherapy and explore possible prognostic factors. The characteristics outcomes...
Abstract Background: On the basis of our patient satisfaction survey, we initiated a quality improvement project at institution to decrease waiting times for patients scheduled chemotherapy. The mean time until started his or her session was 183.5 min. Our aim reduce by 50% (&lt;90 min) over 6-month period and sustain it. Materials Methods: We used multidisciplinary approach identify root causes contributing factors prolonged in chemotherapy unit. implemented three Plan–Do–Study–Act...
Background: Colorectal cancer (CRC) is a significant healthcare burden worldwide and in the Middle East (ME). KRAS mutation confers resistance to epidermal growth factor receptor (EGFR) inhibitors treatment of advanced CRC. Data regarding rate from ME are scattered scarce. We aim collect review all sizable studies evaluating frequency mutations CRC patients ME. Method: A Pubmed Google Scholar search was conducted using keywords including KRAS, K-ras, colorectal East, along with names each...