Objectives We evaluate the feasibility of treatment response prediction using MRI‐based pre‐, post‐, and delta‐radiomic features for locally advanced rectal cancer (LARC) patients treated by neoadjuvant chemoradiation therapy (nCRT). Materials Methods This retrospective study included 53 LARC divided into a training set (Center#1, n = 36) external validation (Center#2, 17). T2‐weighted (T2W) MRI was acquired all patients, 2 weeks before 4 after nCRT. Ninety‐six radiomic features, including...

Objective: Chemotherapy with oxaliplatin is used for a wide range of malignancies. Unlike other platinum derivatives, has less nephrotoxicity. However, in recent years, there have been multiple reports different forms renal toxicity related to this agent. Case Summary: A 40-year-old woman colon adenocarcinoma developed jaundice, hematuria, and oliguria after the 36th cycle chemotherapy. Laboratory data revealed severe anemia, thrombocytopenia, increased creatinine, indirect...

BACKGROUND:Von Hippel-Lindau (VHL) disease is a rare autosomal dominant syndrome manifested by spectrum of benign and malignant tumors. CASE REPORT:The patient presented here was 31-year-old female with unremarkable family history who initially complaining intermittent abdominal pain. Abdominal CT scan revealed an inhomogeneous solid mass (13×9×7 cm) originating from the tail pancreas splenic gastric invasion as well several pancreatic cysts. A nucleotide showed left adrenal involvement. The...

Acute radiation proctitis (ARP) is a usual adverse effect in patients undergoing pelvic radiotherapy. The symptoms include diarrhea, rectal blood or mucus discharge, fecal urgency and tenesmus with pain. Sucralfate, an aluminum-based salt of sucrose octasulfate, cytoprotective agent that forms coating barrier at injured sites by adhering to mucoproteins. It has been used topical management wide variety local lesion. This study was designed evaluate the preventive sucralfate on acute...

Fingerprinting is recognized as an easily accessible means of personal identification; however, fingerprints can be damaged after administration some chemotherapy agents that result in hand and foot syndrome (HFS). Fingerprint loss may also due to reasons unrelated HFS. This study evaluated the incidence fingerprint changes patients treated with capecitabine-containing regimens its relations various grades HFS.Seventy-one who received or without capecitabine part their regimen were enrolled...

BACKGROUND Anal cancer incidence has been on the rise over past few decades. This study aimed to assess anal Papanicolaou (Pap) smear changes in women with high risk for dysplasia and human papillomavirus (HPV) infection.
 METHODS cross-sectional was conducted 121 patients referred Gynecology Oncology Clinic of Imam Hossein Medical Center between 2020 2021 Tehran, Iran, who had cervical vulvar dysplasia, HPV infection, abnormal cytology results were 21 years old. Data analysis performed...

Dear Editor, Orbital metastasis infrequently occurs in breast cancer (1); however is the most common cause of orbital (2-5), followed by lung, prostate, gastrointestinal tract, and skin (melanoma) cancers (6, 7). Definite diagnosis an lesion includes biopsy (either FNA or open biopsy). However, patients with known metastatic cancer, CT scan MRI orbits can frequently show presence a mass, which often involves fat extraocular muscles (4, 5). On other hand, these techniques may not completely...

Introduction: Colorectal cancers (CRCs) are the second cause of malignancy-related deaths and over half CRCs become metastatic. Genetics plays a critical role in understanding metastatic colorectal (MCRCs), as various genetic mutations influence progression treatment responses. While there exists plenty research on CRCs, few studies have focused MCRC patients. The present study aims to provide an overview prevalence KRAS, NRAS, BRAF, MMR Iranian Methods: is descriptive cross-sectional...

Despite extensive research on various brain diseases, a few studies have focused radiomic feature distribution in healthy images. The present study applied novel framework to investigate the robustness and baseline values of features normal magnetic resonance imaging (MRIs) regions. Analyses were performed T1 T2 images including 276 brains 14 volunteers scanned with three scanners using same protocols. divided into 1024 three-dimensional nonoverlap patches pixel size. Seven located thalamus,...

Verrucous carcinoma (VC) is a rare variant of well differentiated squamous cell (SCC) which usually found in oral cavity mucosa. Cutaneous verrucous entity and this paper we report 43 years old man with VCsuperimposed on chronically inflamed skin ileostomy site. Previously, he was operated to treat rectal adenocarcinoma has had for six months. The lesion resected totally during surgical operation closure. Histopathologic examination confirmed the diagnosis cutaneous carcinoma. Post-operative...

Background: Medical image fusion is being widely used for capturing complimentary information from images of different modalities. Combination useful presented in medical the aim techniques, and fused will exhibit more comparison with source images.Objective: In current study, a BEMD-based multi-modal technique utilized. Moreover, Teager-Kaiser energy operator (TKEO) was applied to lower BIMFs. The results were compared six routine methods.Methods: An using bi-dimensional empirical mode...

Currently, neoadjuvant chemoradiotherapy, followed by surgery, is the standard treatment for locally advanced rectal cancer. The use of induction chemotherapy this tumor controversial. In study, benefits and side effects in cancer are evaluated.Twenty-nine patients with 2018-2019 were enrolled study. Initially, they underwent (oxaliplatin 130 mg/m2 every 3 weeks capecitabine 1000 twice a day 14 days 2 courses). Then, chemoradiotherapy (radiotherapy 50.4 Gy/28 5 week concomitant weekly...

Background: Nowadays, medical imaging has an important role in radiotherapy and treatment planning process. Despite the increasing usage of magnetic resonance (MRI) external (RT) design process, computed tomography (CT) remains a basic modality because its relation with electron density value. In conventional radiotherapy, MRI is used functional tissue structures registration on CT image, which causes systematic errors during images. Objectives: The main purpose this paper was to investigate...

In this study, we assess the power of MRI radiomic features for prediction locally advanced rectal cancer (LARC) patients' response to neoadjuvant chemoradiation. T2-Weighted MR images acquired 2 weeks before and 4 after treatment 50 patients were used. The tumor volume was delineated by an experienced radiologist on T2-weighted followed extraction radiomics features, including morphology, first-order, histogram, texture from volumes interest (VOI). First, univariate analysis applied...

Background: Following neoadjuvant chemoradiation, 25% of patients with rectal cancer experience pathologic complete response (pCR). With the appropriate imaging method for this group patients, it would be possible to use less invasive methods. The aim study was assess ability diffusion-weighted magnetic resonance predict pCR after chemoradiation in cancer. Method: In prospective study, 19 were examined. Magnetic performed two stages: one week before start chemoradiotherapy (CRT) and seven...