A5020156264- Research on Leishmaniasis Studies
- Synthesis and Biological Evaluation
- Essential Oils and Antimicrobial Activity
- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Trypanosoma species research and implications
- Phytochemicals and Medicinal Plants
- Synthesis and biological activity
- Nanoparticles: synthesis and applications
- Bioactive Compounds and Antitumor Agents
- Phytochemistry and Biological Activities
- Quinazolinone synthesis and applications
- Phytochemical compounds biological activities
- Food Allergy and Anaphylaxis Research
- RNA modifications and cancer
- Healthcare and Environmental Waste Management
- Chronic Myeloid Leukemia Treatments
- Aquaculture disease management and microbiota
- Ferrocene Chemistry and Applications
- Parasites and Host Interactions
- Ethnobotanical and Medicinal Plants Studies
- Protein Interaction Studies and Fluorescence Analysis
- MicroRNA in disease regulation
- Cancer therapeutics and mechanisms
- Tuberculosis Research and Epidemiology
Saveetha University
2021-2024
SASTRA University
2015-2023
Tamil University
2016-2017
Medicina
2016-2017
ASKA Pharmaceutical (Japan)
2015
Abstract Obesity is considered as an independent risk factor for breast cancer (BCa) and plays a major role in the tumor microenvironment. The etiology mechanisms by which obesity contributes to BCa development not yet understood. Herein, we show that vitro coculture of cells with mature adipocytes (MA‐BCa) increased proliferation, migration, invasive phenotype cells. MA‐BCa led production proinflammatory cytokines chemokines. To identify microRNAs (miRNAs) are modulated presence adipocytes,...
A series of arene ruthenium(<sc>ii</sc>) complexes with<italic>N</italic>-monodentate (AAP) and<italic>N</italic>,<italic>O</italic>- and<italic>N</italic>,<italic>N</italic>-bidentate chelating ligands (AAPS, ADABS, AAPPA and P2P) have been synthesized evaluated for preliminary antileukemia activity against K562 (Human chronic myeloid leukemia cell line).
Silver nanoparticles enhance the anticancer efficacy of shikonin derivatives.
Acetyl shikonin (AS), a naphthoquinone isolated from<italic>Arnebia nobilis</italic>, was tested against visceral leishmaniasis in this study, revealing that AS provides chemo-immunotherapeutic strategy leishmaniasis.
The present study portrays the isolation of four phenylpropanoids - ferulic acid (FA), sinapic (SA), caffeic (CA), and chlorogenic (CHA) from water extract Suaeda maritima (L.) Dumort, a phytochemically less explored Indian medicinal plant. Further, synthesis characterization silver gold nanoparticles using isolated were done. synthesized S. along with nano-conjugated forms compounds exhibited appreciable anti-leukemic activity against K562 cells (human myeloid leukemia). Especially,...
SNP-ApAGP induces M1 polarization in M0 murine macrophages, and can also repolarize M2 macrophages into the phenotype.
In the present work, 16 different plant drugs used by traditional healers from West Bengal were screened through in vitro cell line model. Herbal tribal Purulia, Birbhum and Bankura districts of collected screening against acute myeloid leukemia (AML) (HL-60). Among extracts, bark Flacourtia indica (66.67%), leaf Madhuca longifolia (69.17%), Prosopis cineraria (68.08%) showed better cytotoxicity results than other herbals. Further, time-dependent study maximum selected herbal extracts...
A series of ferulic acid derivatives was synthesized and evaluated for anti-proliferative activity against K562, U937 Hep G2 cells. The compounds were further tested BCR-Abl kinase inhibition.
The research is aimed to assess the joint antibacterial effects of hydrogen peroxide and methanolic stem extract (SNP-MSE)-prepared silver nanoparticles against Klebsiella pneumoniae. Utilizing MSE under sunlight, biogenic were produced, with their properties characterised using FTIR UV-Visible spectroscopies. Turbidimetry determined Minimum Inhibitory Concentration (MIC) SNP-MSE, H2O2, varied combinations at different concentrations. Agar well diffusion assessed zone inhibition. study...
The crude protein from Cocos nucifera L. nutshell was isolated and fractionized by GFC, yielding two peaks, CNP-F1 CNP-F2 having a molecular weight of 43 kDa 46 kDa, respectively as confirmed MALDI-TOF. MS/MS analysis followed MASCOT search gibberellin-20-oxidase serine/threonine kinase-11. (2.5 µg/mL) (0.5 upregulated the pro-inflammatory cytokines (IL-12, IFN-γ) release significantly (p < 0.01) with prompt nitrite generation in murine peritoneal macrophages. It also noteworthy that showed...