- HIV/AIDS Research and Interventions
- HIV, Drug Use, Sexual Risk
- Sex work and related issues
- Adolescent Sexual and Reproductive Health
- Tuberculosis Research and Epidemiology
- Pneumocystis jirovecii pneumonia detection and treatment
- HIV Research and Treatment
- Diagnosis and treatment of tuberculosis
- Economic Growth and Development
- Infectious Diseases and Tuberculosis
- Malaria Research and Control
- International Development and Aid
- Herpesvirus Infections and Treatments
- FinTech, Crowdfunding, Digital Finance
- Clinical Reasoning and Diagnostic Skills
- Public-Private Partnership Projects
- Mosquito-borne diseases and control
- Geophysics and Gravity Measurements
- Leptospirosis research and findings
- Innovations in Medical Education
- Food Security and Health in Diverse Populations
- HIV/AIDS drug development and treatment
- HIV/AIDS Impact and Responses
- Parvovirus B19 Infection Studies
- Poverty, Education, and Child Welfare
Family Health International 360
2024
University of Dar es Salaam
2022
National Institute for Medical Research
2022
Weatherford College
2022
Johns Hopkins University
2018-2020
Instituto Centroamericano de Administración Pública
2013
Columbia University
2013
University of Brescia
2000-2006
To compare pre and post-ART attrition between youth (15-24 years) other patients in HIV care, to investigate factors associated with among youth.Cohort study utilizing routinely collected patient-level data from 160 clinics Kenya, Mozambique, Tanzania, Rwanda.Patients at least 10 years of age enrolling care 01/05 09/10 were included. Attrition (loss follow-up or death 1 year after enrollment ART initiation) was compared using multivariate competing risk (pre-ART) traditional (post-ART) Cox...
We conducted an implementation science study of a community-based ART distribution program for HIV-positive female sex workers (FSW) whereby clients received services through mobile and home-based platforms. compared 6-month treatment-related outcomes in the arm (N = 256) to standard facility-based delivery 253). Those intervention were more likely have initiated (100.0% vs. 71.5%; p 0.04), be currently taking at visit 95.0%; < 0.01), less stopped than 30 days continuously (0.9% 5.7%; 0.008)...
In Tanzania, HIV infection remains much higher among female sex workers (FSWs) than other adult women. addition to HIV, sexually transmitted infections (STIs) and pregnancy prevention are major concerns for FSWs in Tanzania. This study used a programmatic surveillance approach examine protection against STIs/HIV unintended (dual method use) an outreach-based prevention, care, treatment program 119,728 made first visit services served by the Sauti Project from January 2016 September 2017. Of...
A total of 663 human immunodeficiency virus (HIV) care and treatment sites in nine tuberculosis (TB) affected African countries, serving over 900,000 persons living with HIV.To determine the implementation infection control (IC) measures whether program facility characteristics were associated these measures.A survey was conducted to assess presence a TB IC plan, triage practices for suspects, location sputum collection availability particulate respirators. The association examined using...
Introduction Multimonth dispensing (MMD) enables less frequent clinic visits and improved outcomes for people living with HIV, but few children adolescents HIV (CALHIV) are on MMD. At the end of October–December 2019 quarter, only 23% CALHIV receiving antiretroviral therapy (ART) through SIDHAS project sites in Akwa Ibom Cross River states, Nigeria, were In March 2020, during COVID-19, government expanded MMD eligibility to include recommended rapid implementation minimize visits. provided...
Treatment options for anogenital warts in patients with HIV-1 are unsatisfactory because they fail to eradicate latent human papillomavirus.To determine tolerability and efficacy of topical 1% cidofovir cream the treatment external HIV-infected patients.A randomized, placebo-controlled, single-blind, crossover pilot study either or placebo applied once daily 5 days a week 2 weeks followed by observation was performed.Six were randomized six placebo. The latter eventually received cream....
In a multicenter, prospective, randomized, open-label study of isoniazid-preventive therapy (IPT) for latent tuberculosis infection, illegal immigrants from countries where is highly endemic were enrolled at two clinical sites in Northern Italy. Of 208 eligible subjects, 82 received supervised IPT dose 900 mg twice weekly 6 mo (Regimen A), 73 unsupervised B), and 53 300 daily C). Supervised was delivered either one clinic or migrant clinic. The probability completing 26-wk regimen 7, 26, 41%...
Abstract The World Health Organization identified men as an essential group to target with HIV testing and treatment strategies;: who have sex (MSM) male clients of female workers (CFSW) account for 35% new infections globally. Using a cross-sectional design from community-based prevention project in Tanzania (October 2015–September 2018) multivariable logistic regression, we predictors seropositivity among men. Of 1,041,343 on their initial visit the project, 36,905 (3.5%) were MSM; 567,005...
Introduction A programmatic mapping and size estimation study was conducted in 24 districts 5 regions of Tanzania to estimate the locations female sex workers (FSW) men who have with (MSM) inform HIV programming for Key Populations. Methodology Data were collected at two levels: first, interviews informants identify venues where FSWs MSM frequent. Secondly, estimated through FSWs, other venue. The venue estimates aggregated generate ward level estimates. Correction factors then applied...
Introduction Adolescent girls and young women (AGYW) continue to experience a high incidence of HIV in southern eastern Africa, even the context large-scale prevention interventions. In Tanzania, AGYW account for largest proportion new infections have higher risk acquisition than males comparable age. Methods We used routinely collected data from PEPFAR/USAID-funded Sauti Project, large combination program, examine relationship between transactional sex with older partners among Tanzania...
We have assessed prevalence, incidence, and factors associated with increased risk for Chlamydia trachomatis genital infection among female migrant sex workers in Italy. In a prospective, observational study, women were offered free screening sexually transmitted diseases C. was tested by commercial ligase chain reaction assay endocervical specimens. Of the 101 tested, 14 (14%) positive. The odds ratio (OR) significantly higher females under 24 years (OR = 4.31), from Eastern Europe 4.80),...
We have conducted a longitudinal study on factors associated with candidal vaginal colonization, precursor of vaginitis, in cohort HIV-infected women Italy. All consecutive attending single, tertiary care clinical site were offered free screening for sexually transmitted infections and genital disorders every 6–12 months. Candidal colonization was defined as positive culture Candida spp. an asymptomatic woman. From January 1998 to July 2002 we analysed 214 women. The baseline prevalence...
To increase linkage to and retention in antiretroviral therapy (ART) care, we piloted a community-based, ART service delivery intervention for female sex workers (FSWs). At baseline, recruited collected data from 617 FSWs (intervention: 309; comparison: 308) who were HIV positive not on ART. This paper presents (1) the description of model, (2) key descriptive bivariate-level findings baseline FSW cohort. The showed more than half had non-paying partner, less one-third used condom at last...
Adolescent girls and young women (AGYW) aged 15 to 24 years face disproportionately high risks of acquiring HIV other sexually transmitted infections (STIs). A sexual health risk stratification tool can support the development implementation tailored STI prevention services for sub-groups at-risk AGYW. Data were collected among active AGYW in Tanzania between April 2015 March 2017. Exploratory confirmatory factor analyses conducted construct assess latent structure a ten-item scale rapid...
The HIV epidemic in Eastern and Southern Africa is characterized by a high incidence prevalence of infection among adolescent girls young women (AGYW) aged 15-24 years. For instance, some countries, AGYW 20-24 years exceeds that 15-19 2:1. Sauti (meaning voices), project supported the United States Agency for International Development, providing combination prevention interventions to Shinyanga region, Tanzania.The aim this study determine impact cash transfer on risky sexual behavior...
HIV testing is a gateway to care and treatment for people diagnosed with can link those negative results preventive services. Despite the importance of services (HTS) in control, uptake HTS among female sex workers (FSWs) across sub-Saharan Africa (SSA) remains sub-optimal. Concerns about stigma associated work fear loss livelihood if status becomes known, are some restrictions FSWs utilize offered through health facilities. Introduction self-testing (HIVST) may mitigate barriers HTS. This...
Background Poverty and social inequality exacerbate HIV risk among adolescent girls young women (AGYW) in sub-Saharan Africa. Cash transfers can influence the structural determinants of health, thereby reducing risk. Objective This study assessed effectiveness cash transfer delivered along with combination prevention (CHP) interventions risky sexual behavior AGYW Tanzania. The incidence herpes simplex virus type 2 (HSV-2) infection was used as a proxy for behavior. Methods A cluster...
According to UNAIDS, Togo halved AIDS-related deaths among children ages 0-14 from 2010 2020. However, available data show low dolutegravir (DTG)-containing antiretroviral therapy (ART) coverage and viral load suppression (VLS) living with HIV (CLHIV). We analyzed routine facility before after implementation of root-cause-based solutions for improving DTG coverage, (VL) testing VLS CLHIV.We CLHIV ≤14 years October 2019 through September 2022. assessed proportion on ART receiving DTG, VL...
We report a fatal case of malaria in an HIV-coinfected nonimmune traveler. The primary cause death is discussed. importance prevention travelers stressed. Prevention should be regarded as priority area for clinical practice and operational research.