A5055068464- Tuberculosis Research and Epidemiology
- Pneumocystis jirovecii pneumonia detection and treatment
- Infectious Diseases and Tuberculosis
- Diagnosis and treatment of tuberculosis
- Pneumonia and Respiratory Infections
- Mycobacterium research and diagnosis
- Immunodeficiency and Autoimmune Disorders
- Science and Education Research
- HIV/AIDS drug development and treatment
- Trypanosoma species research and implications
- Immune responses and vaccinations
- Healthcare during COVID-19 Pandemic
- Leprosy Research and Treatment
- Reproductive tract infections research
- Coenzyme Q10 studies and effects
- Environmental Sustainability and Education
- Biotechnology and Related Fields
- Health, Nursing, Elderly Care
- Education during COVID-19 pandemic
- Helicobacter pylori-related gastroenterology studies
- Cardiovascular Issues in Pregnancy
- Antibiotics Pharmacokinetics and Efficacy
- Education Pedagogy and Practices
- HIV/AIDS Research and Interventions
- Chronic Disease Management Strategies
Fundação Oswaldo Cruz
2015-2025
Universidade Federal do Rio de Janeiro
1992-2024
Hospital Universitário Clementino Fraga Filho
2001-2024
Universidade Estadual de Campinas (UNICAMP)
2024
Ministério da Saúde
2022
Istituti Clinici Scientifici Maugeri
2020
International Olive Council
2018
University of Brescia
2004-2014
Brescia University
2010-2014
Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
2004-2013
BACKGROUND: Increasing evidence suggests that post-TB lung disease (PTLD) causes significant morbidity and mortality. The aim of these clinical standards is to provide guidance on the assessment management PTLD implementation pulmonary rehabilitation (PR).METHODS: A panel global experts in field TB care PR was identified; 62 participated a Delphi process. 5-point Likert scale used score initial ideas for after several rounds revision document approved (with 100% agreement).RESULTS: Five were...
The epidemiological relevance of tuberculosis is directly related to the socioeconomic profile a given country. Vulnerability influenced by biological factors (e.g., malnutrition, HIV infection, and age) social unhealthy housing, high population density, inappropriate working conditions, lack access health services). In many cases, multiple vulnerabilities occur in conjunction. We propose here reflection on from point view determinants health, as well costs associated with its diagnosis...
BACKGROUND: Optimal drug dosing is important to ensure adequate response treatment, prevent development of resistance and reduce toxicity. The aim these clinical standards provide guidance on 'best practice´ for management TB drugs.METHODS: A panel 57 global experts in the fields microbiology, pharmacology care were identified; 51 participated a Delphi process. 5-point Likert scale was used score draft standards. final document represents broad consensus approved by all participants.RESULTS:...
The high burden of drug-resistant tuberculosis (TB) is a problem to achieve the goals End TB Strategy by 2035. Whether isoniazid monoresistance (Hr) affects anti-TB treatment (ATT) outcomes remains unknown in high-burden countries.
<sec><title>SETTING</title>To appropriately triage and evaluate people with signs or symptoms of pulmonary TB, clinical, laboratory, radiological variables, as well biomarkers, have been prioritised to increase early detection. However, in high TB prevalence areas, few studies used standardised tools assess both sociodemographic characteristics accessible biomarkers comprehensively. This study aimed describe the sociodemographic, radiographic, laboratory associated (PTB)...
Much remains to be understood about COVID-19, but the protective role of antibodies (Igs) is widely accepted in SARS-CoV-2 infection. Igs’ functions are mainly carried out by receptors that bind their Fc portion (FcR), and less attention has been dedicated cytoplasmic members this family. In work, we used single-cell RNA sequencing (scRNA-seq) data discern cell populations bronchoalveolar lavage fluid obtained from healthy individuals patients with mild or severe COVID-19. Then, evaluated...
Non-tuberculous mycobacterial (NTM) infections are increasingly rapidly worldwide. The reason for this phenomenon is unclear, but may include the ageing population, increasing use of immunosuppressive drugs, prevalence diseases that confer susceptibility to NTM, such as COPD and bronchiectasis, growing testing NTM. Awareness NTM related rising still suboptimal. Guidelines from American Thoracic Society Infectious Diseases America have provided a framework evaluating disease care. Compliance...
The aim of these clinical standards is to provide guidance on 'best practice´ for diagnosis, treatment and management drug-susceptible pulmonary TB (PTB).
Tuberculosis (TB) remains a major plague of humanity. People with TB (PWTB) are commonly anemic. Here, we assessed whether the severity anemia in PWTB prior to anti-TB treatment (ATT) was risk factor for an unfavorable outcome.
Rifampicin (RIF) decreases serum concentrations of several antiretroviral drugs. We carried out a prospective, comparative study to define efavirenz (EFV) pharmacokinetics in 16 cases and 13 controls. Cases were HIV tuberculosis (TB) co-infected adults assuming RIF 600 mg once daily EFV 800 daily. Patients on at standard dose without taken as levels plasma assayed by high-performance liquid chromatography (HLPC) predose (Ctrough) 1, 2, 3, 4, 5, 6, 8, 10, 11, 12, 13, 14, 16, 18, 22 24 hours...
It is unclear whether diabetes or prediabetes affects unfavorable treatment outcomes and death in people with tuberculosis (PWTB).
Abstract Background The Xpert MTB/RIF rapid molecular test provides a quantitative measure of Mycobacterium tuberculosis (Mtb) DNA in the form cycle threshold (Ct) values. This information can be translated into mycobacterial load and used as potential risk bacterial spread for (TB) cases, which impact infection control. However, role Ct values assessing Mtb transmission to close contacts has not yet been demonstrated. Methods A prospective study was performed investigate association between...