- Tuberculosis Research and Epidemiology
- Diagnosis and treatment of tuberculosis
- Infectious Diseases and Tuberculosis
- Pneumocystis jirovecii pneumonia detection and treatment
- Pneumonia and Respiratory Infections
- Pleural and Pulmonary Diseases
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Tracheal and airway disorders
- Immunodeficiency and Autoimmune Disorders
- Education Pedagogy and Practices
- Eosinophilic Disorders and Syndromes
- Pneumothorax, Barotrauma, Emphysema
- Inhalation and Respiratory Drug Delivery
- Environmental Sustainability and Education
- Herpesvirus Infections and Treatments
- Otolaryngology and Infectious Diseases
- Psychology and Mental Health
- Hematological disorders and diagnostics
- Migration, Health and Trauma
- Infant Development and Preterm Care
- Social and Economic Solidarity
- Autoimmune and Inflammatory Disorders Research
- Neonatal Respiratory Health Research
- Child Nutrition and Feeding Issues
- Palliative and Oncologic Care
Centro Hospitalar de Vila Nova de Gaia
2016-2025
Administração Regional de Saúde de Lisboa e Vale do Tejo
2016-2025
Instituto Federal do Amazonas
2024
Universidade Estadual do Piau
2024
Direção Geral do Território
2019
Centro Hospitalar do Porto
2018
Universidade do Porto
2017
Instituto Superior de Espinho
2014
Polytechnic Institute of Porto
2013
Philipps University of Marburg
2004
Adverse effects (AE) to TB treatment cause morbidity, mortality and interruption. The aim of these clinical standards is encourage best practise for the diagnosis management AE.
Abstract Background The impact of coexistent IBD and PSC on disease progression prognosis is unclear. This study evaluates outcomes in patients with both conditions, using the novel Risk Estimate Tool (PREsTO) for prognosis. Methods A retrospective multicentric identified IBD-PSC through a national survey. PREsTO was calculated to predict PSC-related liver decompensation, tracked via composite outcome measures. Results Among 77 from six nationwide participating centres, 59 were included,...
The aim of these clinical standards is to provide guidance on 'best practice´ for diagnosis, treatment and management drug-susceptible pulmonary TB (PTB).
Abstract Background In adults, anti–tumor necrosis factor-α (TNF-α) therapy is associated with progression of latent tuberculosis (TB) infection (LTBI) to TB disease, but pediatric data are limited. Methods Retrospective multicenter study within the Paediatric Tuberculosis Network European Trials Group, capturing patients <18 years who developed disease during anti–TNF-α therapy. Results Sixty-six tertiary healthcare institutions providing care for children participated. Nineteen...
Lemierre's syndrome is a potentially severe disease characterised by suppurative thrombophlebitis of the internal jugular vein and subsequent disseminated septic embolisation. The profile this declined in mid-20th century, coinciding with introduction antibiotics. Currently, lack awareness condition delays appropriate treatment worsens prognosis. We report case 12-year-old girl.
Paediatric tuberculosis (TB) disease continues to be a challenge. Difficulties in its diagnosis and limited experience on treatment children are some of the reasons consider need for specialized paediatric TB centres prioritize control programmes, particularly low-incidence countries. We describe cases managed outpatient centre.We conducted retrospective analysis epidemiological clinical data patients aged less than 18 years period ranging from January 2007 June 2017.We identified 46 TB. The...
Hypersensitivity pneumonitis (HP), or extrinsic allergic alveolitis, is an immunologically mediated disease resulting from the inhalation of organic substances that trigger inflammatory response in alveolar wall, bronchioles, and interstitium susceptible individuals. Although HP predominantly occupational disease, seen adulthood, cases children have been described. The diagnosis requires a high degree suspicion. treatment consists avoiding contact with antigen, and, some cases, systemic...
Despite its importance, there are some barriers to patient compliance in preventive therapy (PT) of tuberculosis (TB). The purpose this study was evaluate the appointments, PT and follow-up a pediatric population after TB exposure, followed single outpatient center, subsequent identification determinants. Retrospective analysis all patients who underwent Gaia center from January 2015 June 2016. Patients were divided into two groups: compliant non-compliant, according adherence screening,...
Introdução: A tuberculose (TB) é uma importante causa de mortalidade e morbilidade mundial. Em Portugal, na última década do século xx, assistiu-se a diminuição da incidência TB no grupo etário com menos 15 anos. Material métodos: Análise retrospectiva dos casos doença em crianças internadas Centro Hospitalar Vila Nova Gaia entre 1 Janeiro 2000 31 Dezembro 2007. Analisaram-se os respectivos dados epidemiológicos, clínicos, radioló-gicos, microbiológicos terapêuticos. Resultados: No período...
The authors present a case report of antituberculosis drug-induced liver injury that offered diagnostic challenges (namely, the possibility autoimmune hepatitis) and treatment difficulties.
Confirmation of tuberculosis (TB) in children is difficult, so clinicians use different procedures when deciding to treat. Identify criteria initiate and maintain TB treatment younger than 5 years-old, without diagnosis confirmation. A web-based survey was distributed by email the corresponding authors journal articles on childhood TB. The observations were clustered into disjoint groups, analyzed Ward's method. We sent out 260 questionnaires received 64 (24.6%) responses. Forty-six...
Introdução: Em Portugal, a incidência da infeção complicada por vírus varicela-zoster e respetivos custos é desconhecida. O objetivo deste estudo foi descrever as características clinico-epidemiológicas dos doentes em idade pediátrica internados com o diagnóstico de varicela-zoster.Material Métodos: Estudo descritivo, baseado na análise processos clínicos entre janeiro 1999 julho 2013, varicela-zoster.Resultados: Foram 94 varicela-zoster, dois reativação latente. A mediana 38 (IQR 18 - 65)...
Introduction Sleep paralysis (SP) is relatively frequent condition, occurring either at sleep onset or offset. It occurs least once in a lifetime 40–50% of normal subjects. During SP, the patient experiences gross motor paralysis, while sensory system clear. Hypnogogic and hypnopompic hallucinations are common. This experience might be interpreted as spiritual phenomenon several cultures, each one with different interpretations attributions. Objective The authors revisit clinical...
Childhood tuberculosis (TB) is difficult to diagnose and there are no standardised case definitions. TB records of patients aged >5 years reported in Northern Portugal between 2000 2009 were reviewed. Of the 116 children diagnosed with TB, 72 (62.1%) male; mean age was 2.2 ± 1.2 years. 32 (27.6%) confirmed only 46.7% had provided samples for culture, showing that little effort made obtain specimens confirmation. We could not identify independent factors associated low rate sample collection...