Simon Tiberi
- Tuberculosis Research and Epidemiology
- COVID-19 Clinical Research Studies
- Pneumocystis jirovecii pneumonia detection and treatment
- Infectious Diseases and Tuberculosis
- Pneumonia and Respiratory Infections
- Mycobacterium research and diagnosis
- Maternal Mental Health During Pregnancy and Postpartum
- Long-Term Effects of COVID-19
- SARS-CoV-2 and COVID-19 Research
- COVID-19 Impact on Reproduction
- COVID-19 diagnosis using AI
- Diagnosis and treatment of tuberculosis
- Respiratory Support and Mechanisms
- Biosimilars and Bioanalytical Methods
- Health Systems, Economic Evaluations, Quality of Life
- Pharmacovigilance and Adverse Drug Reactions
- Respiratory viral infections research
- COVID-19 and Mental Health
- Inhalation and Respiratory Drug Delivery
- Intensive Care Unit Cognitive Disorders
- Pregnancy and preeclampsia studies
- PARP inhibition in cancer therapy
- Zoonotic diseases and public health
- Myasthenia Gravis and Thymoma
- Cystic Fibrosis Research Advances
Queen Mary University of London
2018-2024
GlaxoSmithKline (United Kingdom)
2023
Barts Health NHS Trust
2018-2022
Royal London Hospital
2018-2022
National Health Service
2021
Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda
2021
University of Dundee
2021
Medical Research Council
2021
Imperial College Healthcare NHS Trust
2013
Abstract Coronavirus disease has disrupted tuberculosis services globally. Data from 33 centers in 16 countries on 5 continents showed that attendance at was lower during the first 4 months of pandemic 2020 than for same period 2019. Resources are needed to ensure care continuity pandemic.
BACKGROUND: Increasing evidence suggests that post-TB lung disease (PTLD) causes significant morbidity and mortality. The aim of these clinical standards is to provide guidance on the assessment management PTLD implementation pulmonary rehabilitation (PR).METHODS: A panel global experts in field TB care PR was identified; 62 participated a Delphi process. 5-point Likert scale used score initial ideas for after several rounds revision document approved (with 100% agreement).RESULTS: Five were...
Tuberculosis is a chronic infectious disease endemic in Argentina most often localized the lungs, caused by Mycobacterium tuberculosis. It usually afflicts poor population groups and has significant impact on public health. COVID-19 an acute viral SARS-CoV-2 presenting with typical respiratory localization, which eventually displays clinical radiological similarities pulmonary Both entities can have fatal outcome if they are not diagnosed treated time. We present case series where...
ABSTRACT Background Treatment of COVID-19 patients with plasma containing anti-SARS-CoV-2 antibodies may have a beneficial effect on clinical outcomes. We aimed to evaluate the safety and efficacy convalescent in admitted hospital COVID-19. Methods In this randomised, controlled, open-label, platform trial (Randomised Evaluation Therapy [RECOVERY]) several possible treatments are being compared usual care hospitalised UK. Eligible consenting were randomly allocated receive either plus high...
BACKGROUND: Optimal drug dosing is important to ensure adequate response treatment, prevent development of resistance and reduce toxicity. The aim these clinical standards provide guidance on 'best practice´ for management TB drugs.METHODS: A panel 57 global experts in the fields microbiology, pharmacology care were identified; 51 participated a Delphi process. 5-point Likert scale was used score draft standards. final document represents broad consensus approved by all participants.RESULTS:...
Introduction Rapid, robust and continually updated evidence synthesis is required to inform management of COVID-19 in pregnant postpartum women keep pace with the emerging during pandemic. Methods analysis We plan undertake a living systematic review assess prevalence, clinical manifestations, risk factors, rates maternal perinatal complications, potential for mother-to-child transmission, accuracy diagnostic tests effectiveness treatment (including after miscarriage or abortion). will...
The World Health Organization (WHO) recommends countries introduce new anti-TB drugs in the treatment of multidrug-resistant tuberculosis. aim study is to prospectively evaluate effectiveness bedaquiline (and/or delamanid)- containing regimens a large cohort consecutive TB patients treated globally. This observational, prospective based on data collected and provided by Global Tuberculosis Network (GTN) centres analysed twice year. All (including children/adolescents) with and/or delamanid...
Adverse effects (AE) to TB treatment cause morbidity, mortality and interruption. The aim of these clinical standards is encourage best practise for the diagnosis management AE.
The aim of these clinical standards is to provide guidance on 'best practice´ for diagnosis, treatment and management drug-susceptible pulmonary TB (PTB).
The destruction of lung parenchyma caused by TB can result in pulmonary sequelae that are classified as bronchiectasis due to traction (radiological sequelae), and persisting with an inflammatory bronchial component opportunistic infection. There is a lack studies comprehensively analyse whether post-TB differs clinical, prognostic or therapeutic aspects from arising other aetiologies. However, it has been noted tends appear more frequently the upper lobes. In many countries, most frequent...