A5001114094- Tuberculosis Research and Epidemiology
- Advanced Chemical Sensor Technologies
- Infectious Diseases and Tuberculosis
- Biosensors and Analytical Detection
- Pneumonia and Respiratory Infections
- Antibiotics Pharmacokinetics and Efficacy
- Public Health and Nutrition
- Adolescent Sexual and Reproductive Health
- Analytical Chemistry and Chromatography
- HIV, Drug Use, Sexual Risk
- Genetics, Bioinformatics, and Biomedical Research
- HIV/AIDS Research and Interventions
- Diagnosis and treatment of tuberculosis
- vaccines and immunoinformatics approaches
- COVID-19 Prevention and Impact
- Mobile Health and mHealth Applications
- Health Literacy and Information Accessibility
- Gas Sensing Nanomaterials and Sensors
- Computational Drug Discovery Methods
- Diverse Scientific Research Studies
- Analytical Methods in Pharmaceuticals
- Sex work and related issues
- Biochemical and Molecular Research
- Pharmacogenetics and Drug Metabolism
- Traditional Chinese Medicine Studies
Universitas Gadjah Mada
2013-2024
Sebelas Maret University
2022
University of Groningen
2015-2020
University Medical Center Groningen
2015-2020
Yogyakarta State University
2019
The reverse transcription-quantitative polymerase chain reaction (RT-qPCR) approach has been widely used to detect the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). However, instead of using it alone, clinicians often prefer diagnose disease 2019 (COVID-19) by utilizing a combination clinical signs and symptoms, laboratory test, imaging measurement (e.g., chest computed tomography scan), multivariable prediction models, including electronic nose. Here, we report on...
Adverse effects (AE) to TB treatment cause morbidity, mortality and interruption. The aim of these clinical standards is encourage best practise for the diagnosis management AE.
Concomitant food intake influences pharmacokinetics of first-line anti-TB drugs in healthy volunteers. However, treatment-naive TB patients who are starting with drug treatment, data on the influence absent. This study aimed to quantify isoniazid, rifampicin, ethambutol and pyrazinamide treatment. A prospective randomized cross-over pharmacokinetic was conducted adults drug-susceptible TB. They received rifampicin intravenously oral day 1, followed by administration these under fasted fed...
The aim of these clinical standards is to provide guidance on 'best practice´ for diagnosis, treatment and management drug-susceptible pulmonary TB (PTB).
To investigate the potency of a hand-held point-of-care electronic-nose to diagnose pulmonary tuberculosis (PTB) among those suspected PTB.
The 24-h area under the concentration-time curve (AUC24)/minimal inhibitory concentration ratio is best predictive pharmacokinetic/pharmacodynamic (PK/PD) parameter of efficacy first-line anti-tuberculosis (TB) drugs. An optimal sampling strategy (OSS) useful for accurately estimating AUC24; however, OSS has not been developed in fed state or early phase treatment anti-TB drugs.An prediction AUC24 isoniazid, rifampicin, ethambutol and pyrazinamide was TB patients starting treatment. A...
Pyrazinamide is one of the first-line antituberculosis drugs. The efficacy pyrazinamide associated with ratio 24-h area under concentration–time curve (AUC 24 ) to MIC.
The international literature shows that HIV-risk behaviour for women mostly occurs in the context of intimate relationships. Power imbalances social, economic and cultural spheres put at risk. This paper addresses roles male partners women's engagement drug-use drug-related Indonesia. Data were gathered through in-depth interviews with 19 who had injected drugs previous month three sites central Java. Most also drugs. Results show play a significant role initiation drug use, provision drugs,...
Establishing a correct diagnosis is challenging. We aimed to investigate the sensitivity and specificity of routine tuberculosis (TB) diagnostic work-up in lung clinics Indonesia, country with third highest TB burden second gap between notifications cases best estimate incident world. In Province Yogyakarta, we recruited all consecutive patients symptoms suggesting TB, aged ≥18 years. Routine examination consisted clinical evaluation, sputum smear microscopy, chest radiography. For research...
Background Even though conceptually, Tuberculosis (TB) is almost always curable, it currently the world’s leading infectious killer. Patients with pulmonary TB are source of transmission. Approximately 23% population believed to be latently infected bacteria, and 5–15% them will progress at any point in time develop disease. There was a global diagnostic gap 2.9 million between notifications new cases estimated number incident cases, Indonesia carries third-highest this gap. Therefore,...
Digitally delivering healthcare services is very attractive for tuberculosis (TB) management as this disease has a complex diagnosis and lengthy involves multiple medical nonmedical specialists. Especially in low- middle-income countries, eHealth could potentially offer cost-effective solutions to bridge financial, social, time, distance challenges.The goal of the research understand what would make globally applicable gain insight into different TB situations, opportunities, challenges.We...
Abstract Despite its high accuracy to detect the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), reverse transcription-quantitative polymerase chain reaction (RT-qPCR) approach possesses several limitations (e.g., lengthy invasive procedure, reagent availability, and requirement of specialized laboratory, equipment, trained staffs). We developed employed a low-cost, noninvasive method rapidly sniff out disease 2019 (COVID-19) based on portable electronic nose (GeNose C19)...
The global burden of drug-resistant tuberculosis (DR-TB) continues to challenge healthcare systems worldwide. There is a critical need tackle DR-TB by enhancing diagnostics and drug susceptibility testing (DST) capabilities, particularly for emerging drugs. This endeavor crucial optimize the efficacy new therapeutic regimens prevent resistance overuse these invaluable weapons. Despite this urgency, there remains lack comprehensive review on public health measures aimed at improving DST...
The HIV epidemic in Indonesia has risen sharply since 2004, from 2682 cases 2004 to 19,973 2009. main transmission route of is injecting drug use. There little research on women who inject drugs Indonesia. In-depth interviews were carried out with 19 injected three small cities central Java. explored the living conditions and context risk. transcripts coded data thematically analyzed. In this paper we report condom use regular partners. Condom was very low their partners, even though both...
Efficient and cost-effective UV spectrophotometric techniques have been devised using methanol phosphate buffer pH 7.4 to quantify Rifampicin concentrations in the Self Nanoemulsifying Drug Delivery System (SNEDDS), as shown by drug loading efficiency. has a peak wavelength of 474nm with concentration 10-50µg/mL. The relationship between absorbance is linear, high correlation value (r) 0.9998. average percent recovery falls range 99.138% 101.349%. approach suitable for analyzing nanoparticle...
Latar Belakang : Kajian ini menganalisis dan meminimalisasi implementasi performance-based budgeting dari segi mekanisme budgeting, keterbatasan adanya hambatan dengan terwujudnya SPM, evaluasi serta strategi pencapaian SPM. Metode yang digunakan dalam penelitian adalah metode kualitatif pendekatan studi kasus.
 Tujuan menyusun kegiatan program, membuat mencukupi kebutuhan anggaran, memantau mengevaluasi. Evaluasi hasil SPM dapat dilakukan pada uji tahap perencanaan, pelaksanaan, pasca...