The primary objectives of this study were 1) to determine the functional relationship between microvascular blood flow (Q) and arteriolar internal diameter (D) 2) whether conformed a theoretical optimality prediction--that is proportional cube (Q = kD3). Paired velocity measurements in cremaster muscle microvasculature eight normotensive (WKY) hypertensive (SHR) rats made under control conditions following maximal dilation with topically applied adenosine. A total 160 paired flow-diameter...

The standard of care for lymphedema encompasses risk reduction, early detection, Phase-I Complete Decongestive Therapy in a clinical setting, and Phase-II Self Management at home. This review discusses these treatment components, including relevant physiological aspects that form the basis an understanding which are critical to successful outcomes. therapy includes manual lymphatic drainage (MLD), short-stretch compression bandaging, decongestive exercise, skin care, sometimes intermittent...

Pneumatic compression devices (PCDs) are used in the home setting as adjunctive treatment for lymphedema after acute a clinical setting. PCDs range complexity from simple to technologically advanced. The objective of this prospective, randomized study was determine whether an advanced PCD (APCD) provides better outcomes measured by arm edema and tissue water reductions compared standard (SPCD) patients with breast cancer treatment.Subjects were APCD (Flexitouch system, HCPCS E0652) or SPCD...

Background: Quantitative measurements to help detect incipient or latent lymphedema in patients at risk for breast cancer treatment-related (BCRL) are potentially useful supplements clinical assessments. Suitable routine use include arm volumes, bioimpedance, and local tissue water (LTW) determined from the dielectric constant (TDC). Because BCRL initially develops skin subcutis, measures that whole arms may not be optimally sensitive detecting earliest changes. Thus, there is also a need...

OBJECTIVE: Pressure ulcers often occur at sites subjected to pressure and wetness. Although skin wetness is a risk factor for ulcers, the mechanisms effects of versus urine constituents on breakdown unclear. The hypothesis that reduces hardness and, thereby, increases vulnerability underlying blood vessels pressure-induced flow reductions was tested in this study. DESIGN: Pads saturated with water solution mixed main chemical (synthetic urine; s-urine) were applied forearm 10 healthy...

Background Biophysical measures to assess that skin water includes stratum corneum hydration via capacitance ( SC ), dermal tissue dielectric constant TDC and transepidermal loss TEWL ). Since differs among anatomical sites depth we sought determine the site variability of these their relationships. Methods Measurements were done at 17 from forehead foot in 32 supine healthy women. included 1.25 MHz, 300 MHz depths 0.5, 1.5, 2.5 mm . Results Tissue decreased with increasing forehead,...

ObjectiveCharacterization of a non-invasive method quantifying subepidermal moisture (SEM) surrounding stages III and IV pressure ulcers (PrUs) in spinal cord injury (SCI).DesignProspective, single-visit, single-rater, observational study, using repeated-measures analysis.MethodSetting-inpatient units one VA SCI Center.ParticipantsConvenience sample 16 subjects with stage or PrUs over sacrum ischium.InterventionsMeasurement the MoistureMeter-D, hand-held device 300 MHz electromagnetic...

Abstract Background Skin measurements of transepidermal water loss (TEWL) and stratum corneum hydration (SCH) reflect different aspects skin physiology. Since epidermal depends on epidermal‐to‐air vapor gradients, a possible quantitative relationship between TEWL SCH may exist. This investigation's purpose was to test the TEWL‐SCH relationship. Materials Methods were measured noninvasively forearm palmer thenar eminence (hand) in 40 young adults (20 males) along with total body fat...