Purpose: The purpose of this study was to compare optical coherence tomography angiography (OCTA) and indocyanine green (ICGA) for the assessment corneal neovascularization (CoNV). Methods: Patients with CoNV extending at least 3 mm into cornea were included. All patients underwent imaging same visit. Images recorded using AngioVue OCTA system (Optovue, Inc.) long adaptor module (CAM-L). ICGA images fluorescent filters Heidelberg (HRA2 Scanning Laser Ophthalmoscope; Engineering). graded...

We report the development of a Spectral Domain Line Field Optical Coherence Tomography (LF-OCT) system, using broad bandwidth and spatial coherent Super-Continuum (SC) source.With conventional quasi-Continuous Wave (CW) setup we achieve axial resolutions up to 2.1 μm in air 3D volume imaging speeds 213 kA-Scan/s.Furthermore, use single SC pulse, 2 ns duration, temporally gate an OCT B-Scan image 70 A-Scans.This is equivalent 35 GA-Scans/s.We apply CW for high resolution fine structures human...

We have demonstrated for the first time, to our knowledge, use of optical coherence tomography (OCT) as an analytical tool nondestructively characterizing individual paint layer thickness multiple layered automotive paints. A graph-based segmentation method was used automatic analysis distribution top layers solid color The thicknesses measured with OCT were in good agreement microscope and ultrasonic techniques that are current standard automobile industry. Because its high axial resolution...

Optical coherence tomography (OCT) can monitor human donor corneas non-invasively during the de-swelling process following storage for corneal transplantation, but currently only resultant thickness as a function of time is extracted. To visualize and quantify mechanism de-swelling, we present method exploiting nanometer sensitivity Fourier phase in OCT data to image deformation velocities. The technique was demonstrated by showing that osmotic flow through an intact epithelium negligible...

Optical coherence tomography (OCT) has mostly been used for high-speed volume imaging but its profilometry potentials have not fully exploited. This paper demonstrates high precision (as good as ∼50 nm) multi-interface using a Fourier domain OCT system without special antivibration devices. The is up to 2 orders of magnitude better than the depth resolution OCT. Detailed analysis achieved different surfaces presented. profiles are obtained by-product data. advantage in speed and sensitivity...

Automotive coating systems are designed to protect vehicle bodies from corrosion and enhance their aesthetic value. The number, size orientation of small metallic flakes in the base coat paint has a significant effect on appearance automotive bodies. It is important for quality assurance (QA) be able measure properties these flakes, which approximately 10μm radius, yet current QA techniques limited measuring layer thickness. We design develop time-domain (TD) full-field (FF) optical...

The measurement of the thicknesses layers is important for quality assurance industrial coating systems. Current techniques only provide a limited amount information. Here, we show that spectral domain Line Field (LF) Optical Coherence Tomography (OCT) able to return user cross sectional B-Scan image in single shot with no mechanical moving parts. To reliably extract layer from such images automotive paint systems, present an automatic graph search segmentation algorithm. algorithm works...

Bonding wires are one of the most failure-prone components power electronics’ modules, and silicone gel is usually employed to encase bonding wires. To study deformation gel-encased wires, in this article, we report use line-field optical coherence tomography (LF-OCT) technique precisely measure electrical–thermal–mechanical (ETM) An LF-OCT system was developed capture whole cross-sectional image (B-scan) wire sample a single-shot fashion due its advantageous parallel detection scheme. This,...

Purpose: The purpose of this study was to assess the accuracy, repeatability, and performance limits in vivo Mirau ultrahigh axial resolution (UHR) line field spectral domain (LF-SD) optical coherence tomography (OCT) for measurement Bowman's epithelial thickness, provide a reference range these values healthy corneas. Methods: Volunteers with no history evidence corneal disease were included study. An graph search image segmentation central cornea obtained at normal interface vector...

There has been a lot of interest in accurately characterising corneal biomechanical properties under intraocular pressure (IOP) to help better understand ocular pathologies that are associated with elevated IOP. This study investigates the novel use Line-Field Optical Coherence Tomography (LF-OCT) as an elastographic tool for measuring mechanical porcine corneas based on volumetric deformation following varying IOPs. A custom-built LF-OCT was used measure geometrical and surface displacement...

In the laundry industry, colorimetry is a common way to evaluate stain removal efficiency of detergents and cleaning products. For ease visualization, soiling agent treated with dye before measurement. However, it effectively measures rather than removal, cannot provide depth-resolved information sample. this study, we show that full-field (FF) optical coherence tomography (OCT) technique capable measuring effect on cotton fabric by imaging sub-surface features samples. We used broadband...

For any single anterior chamber cross-sectional (tomographic) imaging method, there is a practical compromise between image size and resolution. In order to obtain large field-of-view images of the whole high-resolution fine corneal layers, measurements by multiple devices are currently required. This paper presents novel raster scanning tomographic device that acquires simultaneous Scheimpflug (12.5 mm depth, 50 μm axial resolution in air) spectral domain optical coherence tomography...

The multiple layer paint systems on modern cars serve two end purposes, they firstly protect against corrosion and secondly give the desired visual appearance. To ensure consistent protection appearance, suitable Quality Assurance (QA) measures final product are required. Various (layer thickness consistency, composition, flake statistics, surface profile dryness) parameters of importance, each with specific techniques that can measure one or some them but no technique all most them. Optical...

The line field (LF) design choice for the lateral image formation mechanism (lateral format) has historically been a fraction of whole optical coherence tomography (OCT) field. However, as OCT technology develops, parallelised acquisition LF-OCT formats (LF-time domain (TD)-OCT, LF-spectral (SD)-OCT, LF-swept source (SS)-OCT) offers benefits and capabilities, which may mean it is now becoming more mainstream. Prior reviews on have focused scanning point (SP) and, to lesser extent, full (FF),...

Ultra high axial resolution (UHR) was demonstrated early in the development of optical coherence tomography (OCT), but has not yet reached clinical practice. We present combination supercontinuum light source and line field (LF-) OCT as a technical economical route to get UHR-OCT into clinic other application areas. directly compare images human donor cornea taken with low current generation systems UHR-LF-OCT. These highlight massive information increase UHR-OCT. Application pharmaceutical...

Optical Coherence Tomography (OCT) is a growing family of biophotonic imaging techniques, but in the literature there lack easy-to-use tools to universally directly evaluate device’s theoretical performance for given metric. Modern computing mean that direct numerical modeling can, from first principles, simulate metrics specific device without relying on analytical approximations and/or complexities. Here, we present two different models, along with example MATLAB code reader adapt their...

<h3>Purpose</h3> To investigate the central thickness of Bowman's layer in patients with keratoconus, healthy cornea and other corneal conditions relation to curvature and, epithelial total health, keratoconus (KC) Fuchs' endothelial dystrophy (FED). <h3>Methods</h3> Patients FED dystrophies, subjects were included. Linnik Mirau ultra high axial resolution line field spectral domain optical coherence tomography (UHR-OCT) devices used image cornea, addition commercially available OCT...

Previously we demonstrated a combined scanning-point optical coherence tomography (OCT) and Scheimpflug Imaging (SI) system, to provide cross-section images of the corneal layers whole anterior segment eye simultaneously. However, fully realise benefits this dual imaging modality concept towards clinical practice, it is required that OCT part system can achieve ultra-high axial resolution (<3 µm in air) faster speeds, without using prohibitively expensive components. To this, new device...

We provide a full solution for creating 3D models using 100k Hz A-line rate line-field OCT system. The generated have 50-fold reduction of data size and can be exported AR/VR printing.

For OCM to replace IVCM as a screening tool for DPN, the equivalent nerve en-face projection needs be displayed in real time. Here we show it can done with moderate spec CPU.

Abstract This paper reports the development of a new technique, free space line field spectral domain optical coherence reflectometry (LF-SD-OCR), which is able to produce tomographic like (quasi) images. Furthermore, capabilities and cost benefits technique are demonstrated by constructing handheld LF-SD-OCR device. For glossy paint systems other suitable samples, format produces quasi-tomographic (cross-sectional) imaging through layers, with axial lateral image resolutions 1.3 µm 40...