Ling He

ORCID: 0000-0003-2702-2579
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Research Areas
  • Neuroblastoma Research and Treatments
  • Radiomics and Machine Learning in Medical Imaging
  • Glioma Diagnosis and Treatment
  • Advanced Neuroimaging Techniques and Applications
  • Fermentation and Sensory Analysis
  • Adrenal and Paraganglionic Tumors
  • Functional Brain Connectivity Studies
  • Advanced MRI Techniques and Applications
  • MRI in cancer diagnosis
  • Congenital Heart Disease Studies
  • Phytochemicals and Antioxidant Activities
  • Congenital Diaphragmatic Hernia Studies
  • Postharvest Quality and Shelf Life Management
  • Radiation Dose and Imaging
  • Horticultural and Viticultural Research
  • Esophageal Cancer Research and Treatment
  • Atomic and Subatomic Physics Research
  • Neurofibromatosis and Schwannoma Cases
  • Cancer-related molecular mechanisms research
  • Food Quality and Safety Studies
  • Lung Cancer Diagnosis and Treatment
  • Neonatal Respiratory Health Research
  • Advanced X-ray and CT Imaging
  • Probiotics and Fermented Foods
  • Tracheal and airway disorders

Children's Hospital of Chongqing Medical University
2010-2025

Chongqing Medical University
2010-2025

State Forestry and Grassland Administration
2023-2025

First Affiliated Hospital of GuangXi Medical University
2022-2025

Guangxi Medical University
2022-2025

China Pharmaceutical University
2022-2025

Wuhan University of Technology
2022-2025

Rice University
2025

Northwest A&F University
2014-2024

North Sichuan Medical University
2024

Malolactic fermentation (MLF) is a crucial process to enhance wine quality, and the utilization of indigenous microorganisms has potential characteristics distinct region. Here, MLF performance five Oenococcus oeni strains six synthetic microbial communities (SynComs), were comparatively evaluated in Cabernet Sauvignon wine. In terms malate metabolism rate aroma diversity, strain O. Oe114–46 demonstrated comparable commercial Oe450 PreAc. Furthermore, corresponding SynComs (Oe144–46/LpXJ25)...

10.1016/j.fochx.2024.101369 article EN cc-by-nc-nd Food Chemistry X 2024-04-09

Bacterial pathogens and Mycoplasma pneumoniae are the two main that cause community-acquired pneumonia complicated with pleural effusion (PE) in children, it is important to accurately differentiate between these types of effusions. The aim this study was explore feasibility value a radiomics approach based on non-contrast chest computed tomography (CT) scans differentiation bacterial PE (BPPE) parapneumonic (MPPE) children. clinical CT imaging data hospitalized children detected by from...

10.21037/tp-24-364 article EN Translational Pediatrics 2025-01-01

ABSTRACT Oenococcus oeni, the only species of lactic acid bacteria capable fully completing malolactic fermentation under challenging wine conditions, continues to intrigue researchers owing its remarkable adaptability, particularly in combating stress. However, mechanism underlying superior adaptation stresses still remains elusive due lack viable genetic manipulation tools for this species. In study, we conducted genomic sequencing and resistance phenotype analysis 255 O. oeni isolates...

10.1128/spectrum.03265-24 article EN cc-by Microbiology Spectrum 2025-04-22

Purpose MYCN amplification plays a critical role in defining high-risk subgroup of patients with neuroblastoma. We aimed to develop and validate the CT-based machine learning models for predicting pediatric abdominal Methods A total 172 amplified (n = 47) non-amplified 125) were enrolled. The cohort was randomly stratified sampling into training testing groups. Clinicopathological parameters radiographic features selected construct clinical predictive model. regions interest (ROIs) segmented...

10.3389/fonc.2021.687884 article EN cc-by Frontiers in Oncology 2021-05-24

A plasma membrane-targetable two-photon fluorescent probe for capturing nitric oxide in cells and brain tissues.

10.1039/c8an00905h article EN The Analyst 2018-01-01

To investigate the clinical value of contrast-enhanced computed tomography (CECT) radiomics for predicting response primary lesions to neoadjuvant chemotherapy in hepatoblastoma.

10.1007/s00432-024-05746-x article EN cc-by Journal of Cancer Research and Clinical Oncology 2024-04-30

This study used litchi (Heiye) wine and distilled spirit as raw experimental materials to analyze the volatile aroma compounds. Qualitative quantitative determination of aromatic components was studied using stir bar sportive extraction (SBSE) gas chromatography coupled mass spectrometry (GC/MS). Results indicated that a total 128 different types compounds were observed, which belonged six chemical groups, including 39 esters, 16 alcohols, acids, 22 terpenes, 17 aldehydes ketones, 18 other...

10.1002/fsn3.2361 article EN cc-by Food Science & Nutrition 2021-09-18

Abstract Background To develop and validate a radiomics signature based on computed tomography (CT) for identifying high‐risk neuroblastomas. Procedure This retrospective study included 339 patients with neuroblastomas, who were classified into non‐high‐risk groups according to the revised Children's Oncology Group classification system. These then randomly divided training set ( n = 237) testing 102). Pretherapy CT images of arterial phase segmented by two radiologists. Pyradiomics package...

10.1002/pbc.30280 article EN Pediatric Blood & Cancer 2023-03-07

Daucosterol is a phytosterol glycoside with hepatoprotective properties. The objective of the present study was to confirm role daucosterol in liver failure. Exosomes were isolated from primary mouse umbilical cord mesenchymal stem cells (UCMSCs). A failure model generated by injecting lipopolysaccharide/D-galactosamine. Mice treated exosomes alone or combination (5, 10, 20 mg/kg). Liver tissue damage examined hematoxylin-eosin, Masson's trichrome, and TUNEL staining. levels genes, proteins,...

10.1080/15384047.2023.2184150 article EN cc-by-nc Cancer Biology & Therapy 2023-03-15

Background This study compared anatomical imaging features between high-risk and non-high-risk groups in neuroblastoma with at least one image-defined risk factor (IDRF). It also assessed the diagnostic performance of these identifying group. Methods A retrospective analysis patients IDRF was conducted. Imaging features, including estimated tumor volume IDRFs, were two groups. The using receiver operating characteristic (ROC) curves, areas under ROC curves (AUCs) along their 95% confidence...

10.1177/10732748251315883 article EN cc-by-nc Cancer Control 2025-01-01

Acute Osteofascial Compartment Syndrome (AOCS) stands as a critical surgical emergency, often secondary to various diseases. Its clinical manifestation arises from increased pressure within the fascial compartment, resulting in diminished tissue perfusion and consequential ischemic damage. Presently, diagnostics lack effective biological markers, patients face grim prognosis, experiencing muscle contractures, necrosis, amputations, renal failure, even mortality. The primary treatment,...

10.1186/s40001-025-02285-0 article EN cc-by-nc-nd European journal of medical research 2025-02-05

Objectives The objective was to aggregate the various scenarios that occur during nonconventional public health emergencies (NCPHEs) and analyze evolutionary patterns of NCPHEs better avoid risks reduce social impacts. aim enhance strategies for handling NCPHEs. Study design News reports were crawled obtain scenario elements categorized into spreading stage or derivation stage. Finally, key nodes evolution process analyzed in combination with a corresponding emergency response assessment...

10.3389/fpubh.2025.1489904 article EN cc-by Frontiers in Public Health 2025-02-07

A proposed method for diagnosing sensor faults in the stator winding temperature of a wind turbine is introduced, aiming to address significant issues that arise when such malfunctions occur, affecting overall stable operation turbine. The combines supervisory control and data acquisition (SCADA) with an improved firefly sparrow search algorithm (FISSA)–optimized deep belief network (DBN). input parameters model are determined via Pearson’s correlation coefficient method, whereas...

10.1155/vib/4713545 article EN cc-by Shock and Vibration 2025-01-01
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