A5003370969- Reproductive Biology and Fertility
- Reproductive Health and Technologies
- Ovarian function and disorders
- Assisted Reproductive Technology and Twin Pregnancy
- Sperm and Testicular Function
- Reproductive System and Pregnancy
- Endometriosis Research and Treatment
- Silk-based biomaterials and applications
- RNA Research and Splicing
- Demographic Trends and Gender Preferences
- Social and Intergroup Psychology
- Gender Roles and Identity Studies
- COVID-19 Impact on Reproduction
- Prenatal Screening and Diagnostics
- Uterine Myomas and Treatments
- Estrogen and related hormone effects
- Ethics and Legal Issues in Pediatric Healthcare
- Endometrial and Cervical Cancer Treatments
- Vaccine Coverage and Hesitancy
- Reproductive Health and Contraception
- Ectopic Pregnancy Diagnosis and Management
- Pregnancy and preeclampsia studies
- Gynecological conditions and treatments
- Ovarian cancer diagnosis and treatment
- Media Influence and Health
Medical College of Wisconsin
2016-2024
Washington University in St. Louis
2018-2023
Froedtert Menomonee Falls Hospital
2022
Froedtert Hospital
2022
North Middlesex University Hospital NHS Trust
2016
Abstract Cellular responses to the steroid hormones, estrogen (E2), and progesterone (P4) are governed by their cognate receptor’s transcriptional output. However, feed-forward mechanisms that shape cell-type-specific fulcrums for receptors unidentified. Herein, we found a common mechanism between GREB1 regulates differential effect of on hormones in physiological or pathological context. In (receptive) endometrium, controls P4-responses uterine stroma, affecting endometrial receptivity...
Infertility affects 10% to 15% of couples worldwide, with a male factor contributing up 50% these cases. The primary tool for diagnosing infertility is traditional semen analysis, which reveals sperm concentration, morphology, and motility. However, 25% infertile men are diagnosed as normozoospermic, meaning that, in many cases, normal-appearing fail fertilize an egg. Thus, new information regarding the mechanisms by acquire fertilizing ability needed develop clinically feasible test that...
Background and Methods To evaluate surgical pathologic outcomes of robotic assisted versus open hysterectomy for women with at least class II (BMI >35) III >40) obesity endometrial cancer. Women cancer obesity, treated or between 3/2005 3/2013 were eligible inclusion in this retrospective cohort. Patients reviewed both within the cohort as a separate subset. Data collected on demographics, operative statistics, pathology, post-operative complications, oncologic outcomes. Tests significance...
Since 1992 ART clinics have been required to report outcome data. Our objective was assess practitioners' opinions of the impact public reporting assisted reproductive technology (ART) outcomes on treatment strategies, medical decision-making, and fellow training.Survey study performed in an academic center. Members Society Reproductive Endocrinology Infertility Surgery were recruited participate online survey April 2012.: Categorical responses expressed as percentages. Written categorized...
To comprehensively characterize the DNA virome in semen samples collected for vitro fertilization (IVF).A descriptive clinical study.Single academic fertility center.Twenty-four male partners from couples undergoing IVF.Couples were randomized to receive 1 g of azithromycin (standard care) or no at time baseline IVF assessment. Semen female partners' egg retrieval, and 100 μL sample was used analysis.Detection viruses by ViroCap enrichment viral nucleic acid sequencing. Association between...
Transvaginal ultrasound (TVS) imaging is now recognised as the primary method of choice for ectopic pregnancy and has reported sensitivities >90%. Much published data on performance TVS to diagnose comes from large early units in teaching hospitals. The aim this study was assess diagnosis pregnancies a district general hospital. This retrospective analysis all cases (EP) collected prospectively over 2 years 1st October 2013 30th Sept 2015. Data obtained reports images. 11 237 examinations...
Purpose: To describe a patient with sickle cell disease, prothrombotic disorder, who underwent successful embryo cryopreservation for the purposes of fertility preservation prior to hematopoietic stem transplant. Methods: report case gonadotropin stimulation and using aromatase inhibitor letrozole maintain low serum estradiol minimize thrombotic risk in disease (SCD) history retinal artery thrombosis planning transplant (HSCT). The was given (5 mg daily) as well prophylactic enoxaparin while...
The remarkable potential of human endometrium to undergo spontaneous remodeling is shaped by controlled spatiotemporal gene expression patterns. Although hormone-driven transcription shown govern these patterns, the post-transcriptional processing mRNA transcripts, including splicing in not studied yet. Here, we report that factor, SF3B1 central driving alternative (AS) events are vital for physiological responses endometrium. We show loss activity impairs stromal cell decidualization as...