A5006541498- Veterinary Equine Medical Research
- Periodontal Regeneration and Treatments
- Tendon Structure and Treatment
- Shoulder Injury and Treatment
- Osteoarthritis Treatment and Mechanisms
- Mesenchymal stem cell research
- Platelet Disorders and Treatments
- Hernia repair and management
- Diverticular Disease and Complications
- Sports Performance and Training
- Intestinal and Peritoneal Adhesions
- Mechanics and Biomechanics Studies
- Reproductive Physiology in Livestock
- Intestinal Malrotation and Obstruction Disorders
- Hemostasis and retained surgical items
- Coccidia and coccidiosis research
- Veterinary medicine and infectious diseases
- Urological Disorders and Treatments
- Helminth infection and control
- Microbial infections and disease research
- Meat and Animal Product Quality
- Spine and Intervertebral Disc Pathology
- Venous Thromboembolism Diagnosis and Management
- Vascular anomalies and interventions
- Shoulder and Clavicle Injuries
Universitat Autònoma de Barcelona
2013-2024
Instituto de Investigación Sanitaria Aragón
2016-2018
Universidad de Zaragoza
2016-2018
Maresme Health Consortium
2016
Hospital de Mataró
2016
Hospital de La Ribera
2012-2014
Consorci Institut D'Investigacions Biomediques August Pi I Sunyer
2011
University of Caldas
2010
Washington State University
1989-1995
University of Florida
1988-1989
Abstract Background There is no information on the effects of breed, gender and age cellular content growth factor (GF) release from equine pure-platelet rich plasma (P-PRP) gel (P-PRG). The objectives this study were: 1) to compare composition P-PRP with whole blood platelet poor (PPP); 2) concentration transforming GF beta 1 (TGF-β ) derived isoform BB (PDGF-BB) between treated non-ionic detergent (P-PRP+NID), P-PRG (activated calcium gluconate -CG-), PPP+NID, PPP (PPG), and; 3) evaluate...
Mesenchymal stem cells (MSCs) have a great potential for treating equine musculoskeletal injuries. Although their mechanisms of action are not completely known, immunomodulatory properties appear to be key in functions. The expression immunoregulatory molecules by MSCs is regulated proinflammatory cytokines; so inflammatory priming might improve therapeutic potential. However, environment could also increase MSC immunogenicity and decrease viability differentiation capacity. aim this study...
Mesenchymal stem cells (MSCs) transplantation has become a promising therapeutic choice for musculoskeletal injuries. Joint-related disorders are highly prevalent in horses. Therefore, these animals considered as suitable models testing MSC-based therapies diseases. The aim of this study was to investigate the clinical and inflammatory responses intra-articular single repeat dose administration autologous or pooled allogeneic MSCs healthy equine joints. Six horses were intra-articularly...
Two horses with acute tendinopathy of a superficial digital flexor tendon ( sdft ) and three chronic proximal desmitis the suspensory ligament pdsl were treated by injecting autologous concentrates their platelets into lesions. The lesions monitored ultrasonographically clinically. There significant ultrasonographic clinical improvements in two , but no ; however, they improved clinically became less lame. All had returned to pre‐injury level performance six months after completion...
This study aimed at assessing the effectiveness and safety of repeated administrations allogeneic bone marrow-derived mesenchymal stem cells (BM-MSCs) primed with tumor necrosis factor (TNF)-α interferon-γ in an equine model chemically-induced osteoarthritis. Arthritis was induced both radio-carpal (RC)-joints by amphotericin-B 18 ponies, divided into three groups depending on treatment injected: MSC-naïve (n = 7), MSC-primed 7) control 4). The consisted two phases used one RC-joint each...
Increased synovial fibrinolytic activity (detected by increases in D-Dimer concentrations) has been observed different joint diseases humans and adult horses, presumably order to minimize fibrin deposition within the thus avoid its detrimental effects.To investigate pathway activation sepsis foals measuring concentrations.Eighteen septic with joints, 9 without systemically healthy joint, 3 controls are included.Prospective observational clinical study of admitted for arthritis. Synovial...
Summary The clinical, radiographic, arthroscopic and pathological findings of 10 horses with injury to the cranial cruciate ligament are presented. most consistent clinical signs included moderate severe distension femoropatellar joint a Grade III V out lameness. Craniocaudal instability could be elicited in five under general anaesthesia one conscious horse. Radiographic evaluation stifles revealed that avulsion fracture medial intercondylar eminence was common finding six horses....
Summary After single oral administration of ketoconazole (30 mg/kg bodyweight [bwt]) in 50 ml corn syrup to a healthy mare, the drug was not detected serum. Ketoconazole 0.2 N HC1 administered intragastrically six adult horses five consecutive doses 30 bwt at 12 h intervals. concentrations were measured serum, synovial fluid, peritoneal cerebrospinal fluid (CSF), urine and endometrium. Mean peak serum concentration 3.76 μg/ml 1.5 2 after intragastric administration. 0.87 3 fifth dose....
The medical records of 468 horses that underwent 490 exploratory laparotomies for the correction gastrointestinal diseases were reviewed to search differences between Andalusian and other breeds. seasonal distribution surgical colics their outcome complications also investigated. Bivariant analysis was used compare horses' age, gender breed with type surgery, bowel affected colic, all these variables compared in relation euthanasia during complications, short‐term survival distribution. A...
Inguinal hernias (IHs) and ruptures are a relatively common condition in horses, occurring foals (congenital) adult (acquired) animals. A retrospective observational analysis was conducted on 40 cases that underwent laparoscopic surgery to close the VRs using barbed sutures alone or combined with other techniques. Signalment, clinical presentation, surgery, follow-up data were obtained. In total, fifty-nine closed (alone combination methods), six performed prophylactically forty-four due...
COMUNICACIÓN Uso de concentrados autólogos plaquetas obtenidos mediante el método del tubo
Mesenchymal stem cells (MSCs) are gaining relevance for treating equine joint injuries because of their ability to limit inflammation and stimulate regeneration. Because activates MSC immunoregulatory function, proinflammatory priming could improve efficacy. However, inflammatory molecules present in synovial fluid or added the culture medium might have deleterious effects on MSCs. Therefore, this study was conducted investigate cytokines viability plasticity Equine bone marrow derived MSCs...
Athletic taping is used frequently by human athletes to stabilise, maintain or strengthen soft tissue structures, but empirical evidence supporting any changes in equine kinematics lacking.To assess the effects of athletic fetlock applied an experienced trainer on forelimb mechanics healthy horses.That distal reduces 1) hyperextension joint during stance, 2) flexion swing and 3) ground reaction forces stance.Ground force kinematic data were obtained for 6 horses trotting at 3 m/sec 4...
Summary The objective of this study was to compare swing phase kinetics in the equine forelimb under three shoeing conditions: unshod, flat shoes, eggbar shoes. Flat shoes and were matched for weight. A 60 Hz video camera recorded a full trotting stride sagittal plane during passes per horse each condition. general linear model ANOVA, treating as random variable used detect differences (p <0.05) between conditions. All joints showed significant net joint moments energy bursts, two shod...
A traumatic fracture of C2 was diagnosed radiographically in a 1-year-old German Warm-blood stallion. Fracture configuration difficult to see on survey radiographs. Computed tomography yielded more accurate assessment the and facilitated repair with cortical lag screws. Precise screw placement, avoid spinal cord damage, obtained by use computed tomography. Follow-up radiography revealed normal bone healing, horse dressage schooling 24 months after surgery.
Niveles de factor crecimiento transformante beta-3 y óxido nítrico en cuatro concentrados autólogos plaquetas plasma derivados sangre equina