A5034158060- Cardiac, Anesthesia and Surgical Outcomes
- Aortic aneurysm repair treatments
- Venous Thromboembolism Diagnosis and Management
- Diagnosis and Treatment of Venous Diseases
- Parathyroid Disorders and Treatments
- Pregnancy and preeclampsia studies
- Neuroendocrine regulation and behavior
- Biomarkers in Disease Mechanisms
- RNA modifications and cancer
- Birth, Development, and Health
- Aortic Disease and Treatment Approaches
- Dermatological and Skeletal Disorders
- Atherosclerosis and Cardiovascular Diseases
- Dental Anxiety and Anesthesia Techniques
- Cannabis and Cannabinoid Research
- Cultural Competency in Health Care
- Public Health and Social Inequalities
- Telomeres, Telomerase, and Senescence
- Alcoholism and Thiamine Deficiency
- Bone Metabolism and Diseases
- Frailty in Older Adults
- Inflammasome and immune disorders
- Epigenetics and DNA Methylation
- Agriculture and Biological Studies
- Intraperitoneal and Appendiceal Malignancies
Universidad de Alcalá
2001-2025
Instituto Ramón y Cajal de Investigación Sanitaria
2023-2025
Instituto Cajal
2023-2025
Hospital Universitario Príncipe de Asturias
2020-2025
Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas
2024
Universidad Complutense de Madrid
2024
Instituto de Investigación Sanitaria del Principado de Asturias
2020
Institución Universitaria Esumer
2019
Pancreatic cancer is a malignant neoplasm that, despite its low frequency, has 5-year survival rate of less than 10%. The study different histopathological markers allowed better understanding the onset and development this type tumor as well facilitating an approach to clinical variables based on their diagnostic, prognostic, predictive value. In sense, NLRP3 protein inflammasome been shown be component great relevance in initiation progression pancreatic cancer, although value biomarker...
Calcification is a process of accumulation calcium in tissues and deposition salts by the crystallization PO43− ionized (Ca2+). It crucial development bones teeth. However, pathological calcification can occur almost any soft tissue organism. The better studied vascular calcification, where accumulate intima or medial layer aortic valves, it associated with higher mortality cardiovascular events, including myocardial infarction, stroke, peripheral artery disease (PAD), diabetes chronic...
Preeclampsia, a serious and potentially life-threatening medical complication occurring during pregnancy, is characterized by hypertension often accompanied proteinuria multiorgan dysfunction. It classified into two subtypes based on the timing of diagnosis: early-onset (EO-PE) late-onset preeclampsia (LO-PE). Despite being less severe exhibiting distinct pathophysiological characteristics, LO-PE more prevalent than EO-PE, although both conditions have significant impact placental health....
Sudden infant death syndrome (SIDS) is a type of that occurs suddenly and without any apparent explanation, affecting infants between 28 days life up to year.Recognition this entity includes performing an autopsy determine if there another explanation for the event both external internal examination different tissues search possible histopathological findings.Despite relative success awareness campaigns implementation prevention measures, SIDS still represents one leading causes among...
The ancient Greek educational system, based on paideia , sought to shape well-rounded citizens through the integration of physical and intellectual education, thus promoting a balance between body mind. This philosophy, centered holistic development, was embodied in institutions such as gymnasium, where training not only strengthened but also enhanced character morality young people. In current context, scientific studies have shown that activity within academic environment significantly...
Background: Chronic venous disease (CVD) comprises a set of vascular disorders that affect the system with important local and systemic repercussions. A growing body evidence displays relationship between suffering from CVD marked deregulation immune inflammatory system. In this sense, previous literature has reported some significant changes in level various circulating parameters these patients. However, more research is required to detail deepen complex relationship. Methods: work, we...
Background: Chronic venous disease (CVD) is a vascular disorder common among pregnant women, due to the impairment in function associated with mechanical, hemodynamical, and hormonal changes that occur during pregnancy. CVD linked hypertension, inflammation, oxidative stress, hypoxia, which alter placental structure function, as demonstrated previous works. The placenta fulfills several roles fetal development maternal well-being by mediating nutrient exchange; acting chemical, immunological...
Objectives: The aim of this study was to analyze the prognostic factors survival in patients with peritoneal metastasis (PM) from colorectal cancer (CRC). type relationship between and PM time detection used determine whether it synchronous primary tumor or metachronous. Patients Methods: Retrospective observational study. It included treated for adenocarcinoma diagnosed January 2005 December 2019 who presented at diagnosis during follow-up. Variables, such as sex, age, differentiation...
The connection between physical activity and cognitive function has become a focus of attention in educational research recent years. Regular exercise been shown to have significant positive effects on health, but it also appears impact academic performance. Of all the modalities, resistance training drawn interest for its ability improve cerebral abilities addition well-being. However, there is limited available knowledge exploring relationship regimens This narrative review aims...
Psychosis refers to a mental health condition characterized by loss of touch with reality, comprising delusions, hallucinations, disorganized thought, behavior, catatonia, and negative symptoms. A first-episode psychosis (FEP) is rare that can trigger adverse outcomes both for the mother newborn. Previously, we demonstrated existence histopathological changes in placenta pregnant women who suffer an FEP pregnancy. Altered levels oxytocin (OXT) vasopressin (AVP) have been detected patients...
Preeclampsia (PE) is a complex multisystem disease characterized by hypertension of sudden onset (>20 weeks' gestation) coupled with the presence at least one additional complication, such as proteinuria, maternal organ dysfunction, or uteroplacental dysfunction. Hypertensive states during pregnancy carry life-threatening risks for both mother and baby. The pathogenesis PE develops due to dysfunctional placenta aberrant architecture that releases factors contributing endothelial an...
Objectives Chronic venous disease (CVeD) is a multifactorial and debilitating condition that has high prevalence in Western countries an important associated socioeconomic burden. Varicose veins (VVs) are the most common manifestations of CVeD. Pathologically, many morphological functional changes have been described VVs, which notably affect wall integrity. Previous studies found several molecular alterations negatively normal cell signaling pathways. Insulin receptor substrate (IRS)-4...
To determine the degree of long-term health-related quality life (HRQoL) patients undergoing surgery for abdominal aortic aneurysm (AAA) and to analyze results according type treatment, namely, open repair (OAR) or endoprosthesis (EVAR).