A5043722955- Pharmaceutical studies and practices
- Pharmaceutical Practices and Patient Outcomes
- Child and Adolescent Health
- Patient Safety and Medication Errors
- Pneumonia and Respiratory Infections
- Neonatal Respiratory Health Research
- Vaccine Coverage and Hesitancy
- Safe Handling of Antineoplastic Drugs
- Retinopathy of Prematurity Studies
- Child Nutrition and Feeding Issues
- Neonatal Health and Biochemistry
- Bacterial Infections and Vaccines
- Clinical Nutrition and Gastroenterology
- Antibiotics Pharmacokinetics and Efficacy
- Animal Genetics and Reproduction
- Pharmacological Effects and Toxicity Studies
- Infant Nutrition and Health
- Pregnancy and Medication Impact
- Lysosomal Storage Disorders Research
- Pediatric Pain Management Techniques
- Nosocomial Infections in ICU
- Microscopic Colitis
- Inflammatory Bowel Disease
- Aquaculture disease management and microbiota
- Immunodeficiency and Autoimmune Disorders
Vall d'Hebron Hospital Universitari
2005-2025
Adrenal insufficiency is usually diagnosed in children who will need lifelong hydrocortisone therapy. However, medicines for pediatrics, terms of dosage and acceptability, are currently unavailable.
Tocilizumab is an IL-6 receptor inhibitor agent which has been proposed as a candidate to stop the inflammatory phase of infection by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). However, safety data tocilizumab in pregnant women and their newborn are scarce. We aimed describe maternal neonatal outcomes associated with treatment COVID-19.
Pediatric patients are more likely to experience medication-related errors and serious associated harms. The identification of high-risk medications (HRM) their study in special populations, such as children with excess body weight (EBW), is a part safety improvement strategies. To generate, through consensus technique structured by an interdisciplinary group pediatricians hospital pharmacists, operational updated list HRM for use over 2 years age. document was collaboration project between...
Although heart failure (HF) and supraventricular tachycardias (SVT) are associated with high morbidity mortality in pediatrics, especially, children under 6 months; the efficacy of available treatments is limited, requiring use off-label therapies. The aim study to investigate efficacy, dosage, safety ivabradine patients months age HF or SVT. Retrospective observational study, which included SVT who received between January 2020 - May 2024. Demographic, clinical, treatment-related variables...
Teduglutide (Revestive®) is a glucagon-like peptide-2 analogue used for the treatment of short bowel syndrome, rare life-threatening condition in which amount functional gut too to enable proper absorption nutrients and fluids. During handling prior administration patient hospital, it possible that peptide-based medicines may be exposed environmental stress conditions could affect their quality. It therefore essential carry out testing studies evaluate how such respond these stresses. For...
Urinary tract infections (UTIs) associated with indwelling urinary catheterization (IUC) in premature newborns (PNBs) pose a significant challenge neonatal intensive care units (NICUs) due to the vulnerability of this population and necessity invasive procedures. While bacterial UTIs have historically been predominant, there is rising incidence fungal pathogens, particularly non- albicans Candida strains like glabrata tropicalis , attributed broad-spectrum antibiotic use. Diagnosis PNB...
Many drugs prescribed in pediatric units do not meet the conditions of use defined their corresponding prescription information sheets, or has been approved by Spanish Health Authorities. The lack clinical trials children, and adequate dosage forms, reduces drug safety, assuming both physician pharmacist responsibility for use.To assess status within a neonatal intensive care unit third-level hospital.A 3-months prospective study was performed, collected from all admitted children along four...
Nephrotoxicity is the most frequent serious adverse effect associated with amphotericin B deoxycholate treatment, for this reason, in recent years it has been relegated from routine clinical practice and replaced by new liposomal formulations that have less nephrotoxicity. Nevertheless, dyselectrolytemia are a of use usually resolved withdrawal drug.We present preterm neonate 25 weeks gestation, preserved renal function electrolytes within normal limits gestational age except mild...
Experiments were conducted to investigate vaccination and dietary modification as possible prophylactic measures minimize bacterial kidney disease (BKD) infection occurrence severity in Atlantic Salmon. In the nutritional studies, a commercial diet six diets containing various levels of calcium, magnesium, zinc, iron, copper, maganese, cobalt, iodine, fluorine fed post-yearling salmon. After administration different diets, fish high iodine (4.5 mg/kg feed) mg/kg) had lower prevalence...
The main aim was to compare the effects of two parenteral lipid emulsions on retinopathy prematurity (ROP) incidence, severity, and need for treatment. Secondary effect weight gain in first 6 weeks life.
Oral administration of hypertonic solutions can contribute to intestinal damage in the initial stages neonatal necrotizing enterocolitis. The purpose this study is determine osmolality oral liquid dosage forms used a division neonatology and establish some recommendations for their dilution.The 26 has been measured using freezing-point depression method.Oral present an greater than 350 mOsm/kg H2O. 19.2% all analysed presented lower 1500 H2O, 80.7% were over that figure, while 23% extremely...
To study the association between gestational age (GA) and weight at birth development of retinopathy prematurity (ROP), in particular link postnatal gain during first 6 weeks need for ROP treatment.Retrospective observational premature infants who underwent ophthalmoscopy Hospital Universitari Vall d'Hebron Barcelona, Spain, June 2017 December 2018. We collected data on obstetric characteristics, comorbidities, GA birth, weekly weeks.Ninety patients with a mean ± SD 26.87 1.90 884.29 227.40...
<h3>Case</h3> A child with Niemann-Pick disease type C was started on miglustat therapy at the age of 2 years. Intrathecal administration hydroxypropyl-β-cyclodextrin added 5 months later. The initial dose 175 mg gradually increased over first 6 to reach 325 mg. drug administered every 15 days, and patient received 43 doses. slight delay in progression seen during year intrathecal hydroxypropyl-β-cyclodextrin. However, additional symptoms have emerged since that time, suggesting a lack...
Teduglutide, the active ingredient of medicine Revestive® (5 mg), is a recombinant therapeutic peptide that mimics effects endogenous glucagon-like 2 (GLP-2). It stimulates intestinal growth, adaptation and function in patients with Short Bowel Syndrome who are dependent on parenteral nutrition. The Summary Product Characteristics recommends immediate use reconstituted solutions discarding any subsequent surplus. This study aims to carry out long-term stability reproduces hospital conditions...
The main aim was to compare the effects of 2 parenteral lipid emulsions on retinopathy prematurity (ROP) incidence, severity, and need for treatment. Secondary effect weight gain in first 6 weeks life. Single-center, observational, retrospective study analyzing preterm infants with a gestational age (GA) < 31 birth 1251 g born between April 2015 December 2018. infants' medical records were reviewed collect clinical data. Parenteral nutrition (PN) details obtained from hospital pharmacy...
Objective:To evaluate the physical compatibility between intravenous magnesium sulfate and potassium sodium phosphate, a common electrolyte supplementation in pediatric intensive care units. Study design: Magnesium was mixed separately with phosphate at ratios of 1:1, 1:4, 4:1. Binary mixtures were prepared, triplicate under sterile conditions, by permuting order addition. The undiluted pure drugs used as controls for possible sequence effects. Visual changes, turbidity, pH assessed...